Synchrotron-based characterization of arthroprosthetic CoCrMo particles in human bone marrow.
Journal
Journal of materials science. Materials in medicine
ISSN: 1573-4838
Titre abrégé: J Mater Sci Mater Med
Pays: United States
ID NLM: 9013087
Informations de publication
Date de publication:
13 Jun 2022
13 Jun 2022
Historique:
received:
19
12
2021
accepted:
18
05
2022
entrez:
12
6
2022
pubmed:
13
6
2022
medline:
15
6
2022
Statut:
epublish
Résumé
Particles released from cobalt-chromium-molybdenum (CoCrMo) alloys are considered common elicitors of chronic inflammatory adverse effects. There is a lack of data demonstrating particle numbers, size distribution and elemental composition of bone marrow resident particles which would allow for implementation of clinically relevant test strategies in bone marrow models at different degrees of exposure. The aim of this study was to investigate metal particle exposure in human periprosthetic bone marrow of three types of arthroplasty implants. Periprosthetic bone marrow sections from eight patients exposed to CoCrMo particles were analyzed via spatially resolved and synchrotron-based nanoscopic X-ray fluorescence imaging. These analyses revealed lognormal particle size distribution patterns predominantly towards the nanoscale. Analyses of particle numbers and normalization to bone marrow volume and bone marrow cell number indicated particle concentrations of up to 1 × 10
Identifiants
pubmed: 35691951
doi: 10.1007/s10856-022-06675-2
pii: 10.1007/s10856-022-06675-2
pmc: PMC9189090
doi:
Substances chimiques
Alloys
0
Metals
0
Chromium
0R0008Q3JB
Vitallium
12629-02-6
Cobalt
3G0H8C9362
Molybdenum
81AH48963U
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
54Subventions
Organisme : NIMHD NIH HHS
ID : L60 MD001161
Pays : United States
Informations de copyright
© 2022. The Author(s).
Références
Chem Rev. 2018 Apr 11;118(7):3209-3250
pubmed: 29517229
J Arthroplasty. 2016 Aug;31(8):1717-21
pubmed: 26869063
Annu Rev Pharmacol Toxicol. 2021 Jan 6;61:269-289
pubmed: 32841092
Acta Biomater. 2019 Oct 15;98:284-293
pubmed: 31173961
J Funct Biomater. 2015 Jun 26;6(3):486-99
pubmed: 26132653
Materials (Basel). 2019 Jan 28;12(3):
pubmed: 30696087
Semin Immunol. 2017 Dec;34:52-60
pubmed: 29066063
Bone Joint J. 2015 Oct;97-B(10):1350-7
pubmed: 26430009
Curr Allergy Asthma Rep. 2017 Nov 11;17(12):83
pubmed: 29129023
Front Pharmacol. 2021 Feb 19;12:627781
pubmed: 33679407
J Arthroplasty. 1995 Feb;10(1):75-82
pubmed: 7730834
J Arthroplasty. 2015 Aug;30(8):1470-5
pubmed: 25817187
BMC Clin Pathol. 2018 Aug 25;18:7
pubmed: 30158837
EFORT Open Rev. 2021 Jun 28;6(6):399-419
pubmed: 34267931
J Arthroplasty. 2018 Oct;33(10):3313-3319
pubmed: 29871834
J Nanopart Res. 2012 Jan;14(1):1-10
pubmed: 22448125
Nanoscale. 2014 Jun 21;6(12):7052-61
pubmed: 24842463
Regul Toxicol Pharmacol. 2021 Jun;122:104910
pubmed: 33662479
Front Immunol. 2019 Sep 18;10:2232
pubmed: 31620137
Adv Sci (Weinh). 2020 Aug 03;7(20):2000412
pubmed: 33101844
J Synchrotron Radiat. 2016 Jan;23(1):344-52
pubmed: 26698084
Genes (Basel). 2018 May 10;9(5):
pubmed: 29748516
J Biomed Mater Res B Appl Biomater. 2018 Apr;106(3):986-996
pubmed: 28480531
J Arthroplasty. 2021 Oct;36(10):3498-3506
pubmed: 34238620
Exp Hematol. 2018 Dec;68:51-61
pubmed: 30243574
J Bone Joint Surg Am. 2014 Mar 19;96(6):488-93
pubmed: 24647505
J Arthroplasty. 2020 Jun;35(6S):S284-S288
pubmed: 32113811
J Orthop Res. 2020 Jul;38(7):1436-1444
pubmed: 32437026
J Biomed Mater Res. 1998 Oct;42(1):103-11
pubmed: 9740012
J Arthroplasty. 2016 Dec;31(12):2900-2906
pubmed: 27426028
Anal Chem. 2020 Nov 3;92(21):14432-14443
pubmed: 32970419
J Arthroplasty. 1988;3(4):327-36
pubmed: 3241170
Biomed Res Int. 2015;2015:910156
pubmed: 25866822
Hip Int. 2018 Jul;28(4):352-362
pubmed: 29192727
Rheumatol Ther. 2017 Jun;4(1):45-56
pubmed: 28364382
Bone Jt Open. 2021 Oct;2(10):785-795
pubmed: 34587776
Pathol Res Pract. 2014 Dec;210(12):779-86
pubmed: 25454771
J Bone Joint Surg Br. 2012 Jul;94(7):895-900
pubmed: 22733942
Small. 2014 Nov 12;10(21):4340-51
pubmed: 24990430
Nanomedicine. 2015 Jul;11(5):1201-15
pubmed: 25744761
Nanomedicine. 2017 Apr;13(3):1205-1217
pubmed: 27888094
Immunobiology. 2017 Jun;222(6):814-822
pubmed: 27890297
Biomaterials. 2016 Aug;98:31-40
pubmed: 27179133
BMC Musculoskelet Disord. 2015 Aug 12;16:192
pubmed: 26265062
Bone Joint Res. 2017 Jul;6(7):405-413
pubmed: 28710154