Therapeutic Implications of Curcumin in the Treatment of Inflammatory Eye Diseases: A Review.
Curcuma longa L
Curcumin
cornea
eye
retina
turmeric
Journal
Current pharmaceutical biotechnology
ISSN: 1873-4316
Titre abrégé: Curr Pharm Biotechnol
Pays: Netherlands
ID NLM: 100960530
Informations de publication
Date de publication:
2023
2023
Historique:
received:
01
10
2021
revised:
16
03
2022
accepted:
31
03
2022
pubmed:
14
6
2022
medline:
16
3
2023
entrez:
13
6
2022
Statut:
ppublish
Résumé
Curcumin is the main active constituent of the medicinal plant Curcuma longa L., used traditionally as a medicinal spice in several ancient civilizations. Different preclinical and clinical studies support the anti-inflammatory properties of curcumin in various inflammatory diseases. As inflammation has an essential role in the pathophysiology of many ocular diseases, curcumin has been suggested as a promising therapeutic agent with anti-inflammatory properties. Based on the extent of experimental and clinical evidence, curcumin can exert protective effects against the corneal, uveal, retinal, optic nerve, orbital, and lacrimal gland inflammatory disorders. Herein, the available literature on the beneficial effects of curcumin in inflammatory eye diseases is reviewed. The limitations and future directions of these investigations are also discussed.
Identifiants
pubmed: 35692138
pii: CPB-EPUB-124291
doi: 10.2174/1389201023666220609085614
doi:
Substances chimiques
Curcumin
IT942ZTH98
Anti-Inflammatory Agents
0
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
553-561Informations de copyright
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