Therapeutic Implications of Curcumin in the Treatment of Inflammatory Eye Diseases: A Review.


Journal

Current pharmaceutical biotechnology
ISSN: 1873-4316
Titre abrégé: Curr Pharm Biotechnol
Pays: Netherlands
ID NLM: 100960530

Informations de publication

Date de publication:
2023
Historique:
received: 01 10 2021
revised: 16 03 2022
accepted: 31 03 2022
pubmed: 14 6 2022
medline: 16 3 2023
entrez: 13 6 2022
Statut: ppublish

Résumé

Curcumin is the main active constituent of the medicinal plant Curcuma longa L., used traditionally as a medicinal spice in several ancient civilizations. Different preclinical and clinical studies support the anti-inflammatory properties of curcumin in various inflammatory diseases. As inflammation has an essential role in the pathophysiology of many ocular diseases, curcumin has been suggested as a promising therapeutic agent with anti-inflammatory properties. Based on the extent of experimental and clinical evidence, curcumin can exert protective effects against the corneal, uveal, retinal, optic nerve, orbital, and lacrimal gland inflammatory disorders. Herein, the available literature on the beneficial effects of curcumin in inflammatory eye diseases is reviewed. The limitations and future directions of these investigations are also discussed.

Identifiants

pubmed: 35692138
pii: CPB-EPUB-124291
doi: 10.2174/1389201023666220609085614
doi:

Substances chimiques

Curcumin IT942ZTH98
Anti-Inflammatory Agents 0

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

553-561

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Mojtaba Heydari (M)

Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Mohammad Reza Khalili (MR)

Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Mohammad Hossein Nowroozzadeh (MH)

Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Shahram Bamdad (S)

Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Amirhossein Sahebkar (A)

Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Mohammad Ali Shariati (MA)

K.G. Razumovsky Moscow State University of Technologies and Management (the First Cossack University), Moscow 109004, Russian Federation.

Muthu Thiruvengadam (M)

Department of Applied Bioscience, College of Life and Environmental Sciences, Konkuk University, Seoul, 05029, Korea.
Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 600077, India.

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Classifications MeSH