Effect of matcha consumption on gut microbiota in healthy Japanese individuals: study protocol for a double-blind crossover interventional study.
double-blind crossover interventional study
dysbiosis
matcha
microbiota
Journal
Journal of clinical biochemistry and nutrition
ISSN: 0912-0009
Titre abrégé: J Clin Biochem Nutr
Pays: Japan
ID NLM: 8700907
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
10
08
2021
accepted:
13
09
2021
entrez:
13
6
2022
pubmed:
14
6
2022
medline:
14
6
2022
Statut:
ppublish
Résumé
This study compares and clarifies the changes in intestinal flora resulting from the continuous consumption of two types of matcha. Healthy adults will consume two types of matcha tea for four weeks, and differences in the intestinal microflora before and after drinking will be compared. Gut microbiota will be identified using next-generation sequencing. Phylogenetic classification of the enterobacteria will be performed based on sequence similarities. The relative proportions of the classified enterobacteria to the total nucleotide sequences will be compared between the samples obtained from the two groups consuming different matcha. The continuous consumption of matcha may improve dysbiosis and prevent atherosclerosis. The effects may vary according to the type of matcha used. Trial registration: The study was registered with university hospital medical information network (UMIN) (UMIN000040303), and all participants gave their written informed consent. Registered 1 November 2020, https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000045982.
Identifiants
pubmed: 35692672
doi: 10.3164/jcbn.21-110
pii: DN/JST.JSTAGE/jcbn/21-110
pmc: PMC9130063
doi:
Types de publication
Journal Article
Langues
eng
Pagination
262-265Informations de copyright
Copyright © 2022 JCBN.
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