Heritability of maxillary dental cephalometric variables among monozygotic twins, dizygotic twins and their siblings.
Epigenetics
Heritability
Maxillary canine position
Twin study
Journal
Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
received:
23
12
2021
accepted:
07
06
2022
pubmed:
14
6
2022
medline:
5
10
2022
entrez:
13
6
2022
Statut:
ppublish
Résumé
The purpose of this study was to investigate the heritability of dental cephalometric variables by analyzing vertical linear measurements and angular measurements of the upper incisor, canine, and first molar. Among the 553 Korean patients who participated in twin studies conducted at Samsung Medical Center, 150 patients had their lateral cephalometric radiograph data included in this study. The group was comprised of 36 monozygotic (MZ) twins (males, 16 pairs; females, 20 pairs), 13 dizygotic (DZ) twins (males, 7 pairs; females, 6 pairs), and 26 same-sex sibling pairs (males, 11 pairs; females, 15 pairs). All patients were over 20 years old with a mean age of 39.75 years. Lateral cephalometric diagrams and linear measurements (6 vertical factors, 6 horizontal factors) were taken. Three axial planes were measured for each tooth; intraclass correlation coefficients (ICCs) were obtained for each group and heritability was calculated using Falconer's method. ICCs of vertical linear measurements (average 0.837, P < 0.01) and the tooth axis of the central incisor and canine (average 0.679, P < 0.001) were higher in the MZ group compared to the DZ and sibling groups; thus, these variables showed high heritability. Orthodontic treatment aiming to alter the tooth axis of the maxillary central incisor or canine or other vertical factors with greater heritability can be difficult, requiring strategic treatment planning to achieve desired treatment outcome and stability. The active early treatment to gain tooth eruption space can lead to normal tooth position.
Identifiants
pubmed: 35695936
doi: 10.1007/s00784-022-04579-7
pii: 10.1007/s00784-022-04579-7
doi:
Types de publication
Journal Article
Twin Study
Langues
eng
Pagination
6275-6281Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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