Intra-abdominal hypertension in cardiac surgery patients: a multicenter observational sub-study of the Accuryn registry.

Abdominal compartment syndrome Cardiac surgery Intra-abdominal hypertension; IAH Intra-abdominal pressure; IAP Perioperative Real-time monitoring

Journal

Journal of clinical monitoring and computing
ISSN: 1573-2614
Titre abrégé: J Clin Monit Comput
Pays: Netherlands
ID NLM: 9806357

Informations de publication

Date de publication:
02 2023
Historique:
received: 25 01 2022
accepted: 06 05 2022
pubmed: 14 6 2022
medline: 24 1 2023
entrez: 13 6 2022
Statut: ppublish

Résumé

Intra-abdominal hypertension (IAH) is frequently present in the critically ill and is associated with increased morbidity and mortality. Conventionally, intermittent 'spot-check' manual measurements of bladder pressure in those perceived as high risk are used as surrogates for intra-abdominal pressure (IAP). True patterns of IAH remain unknown. We explored the incidence of IAH in cardiac surgery patients and describe the intra-and postoperative course of IAP using a novel, high frequency, automated bladder pressure measurement system. Sub-analysis of a prospective, multicenter, observational study (NCT04669548) conducted in three large academic medical centers. Continuous urinary output (CUO) and IAP measurements were observed using the Accuryn Monitoring System (Potrero Medical, Hayward, CA). Data collected included demographics, hemodynamic support, and high-frequency IAP and CUO. One Hundred Thirty-Seven cardiac surgery patients were analyzed intraoperatively and followed 48 h postoperatively in the intensive care unit. Median age was 66.4 [58.3, 72.0] years, and 61% were men. Median Foley catheter dwell time was 56.0 [46.8, 77.5] hours, and median baseline IAP was 6.3 [4.0, 8.1] mmHg. 93% (128/137) of patients were in IAH grade I, 82% (113/137) in grade II, 39% (53/137) in grade III, and 5% (7/137) in grade IV for at least 12 cumulative hours. For maximum consecutive duration of IAH, 84% (115/137) of patients spent at least 12 h in grade I, 62% (85/137) in grade II, 18% (25/137) in grade III, and 2% (3/137) in grade IV IAH. During the first 48 h after cardiac surgery, IAH is common and persistent. Improved and automated monitoring of IAP will increase the detection of IAH-which normally would remain undetected using traditional intermittent monitoring methods.

Identifiants

pubmed: 35695943
doi: 10.1007/s10877-022-00878-2
pii: 10.1007/s10877-022-00878-2
pmc: PMC9852117
doi:

Substances chimiques

cupric oxide V1XJQ704R4

Banques de données

ClinicalTrials.gov
['NCT04669548']

Types de publication

Observational Study Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

189-199

Investigateurs

Lynnette C Harris (LC)
Nia Sweatt (N)
Kelsey Flores (K)
Brandon Reeves (B)
Bruce Cusson (B)
Lillian Nosow (L)
Jessica Fanelli (J)
Lauren Sands (L)
Jacob Fowler (J)
Easton Howard (E)
Samuel Robinson (S)
Anthony Wachnik (A)
Madeline Fram (M)
Rohesh Fernando (R)
Chandrika Garner (C)
Bryan Marchant (B)
Benjamin Morris (B)
Amit Saha (A)
Katherine Egan (K)
Bev Ann Blackwell (BA)

Informations de copyright

© 2022. The Author(s).

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Auteurs

Ashish K Khanna (AK)

Department of Anesthesiology, Section on Critical Care Medicine, Wake Forest School of Medicine, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.
Outcomes Research Consortium, Cleveland, OH, USA.

Steven Minear (S)

Department of Anesthesiology, Cleveland Clinic Florida, Weston Hospital, 2950 Cleveland Clinic Boulevard, Weston, FL, USA.

Andrea Kurz (A)

Departments of General Anesthesiology and Outcomes Research, Cleveland Clinic, Anesthesiology Institute, 9500 Euclid Avenue/E-31, Cleveland, OH, USA. ak@or.org.
Department of Anesthesiology, Emergency Medicine and Intensive Care Medicine, Medical University Graz, Graz, Austria. ak@or.org.

Vanessa Moll (V)

Potrero Medical, Hayward, CA, USA.
Department of Anesthesiology, Division of Critical Care Medicine, Emory University School of Medicine, Atlanta, GA, USA.

Kelly Stanton (K)

Potrero Medical, Hayward, CA, USA.

Leina Essakalli (L)

Potrero Medical, Hayward, CA, USA.

Amit Prabhakar (A)

Department of Anesthesiology, Division of Critical Care Medicine, Emory University School of Medicine, Atlanta, GA, USA.

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