Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.

Creatinine Diabetes Mellitus Diabetic Nephropathies / genetics Genome-Wide Association Study Glomerular Filtration Rate / genetics Humans Kidney

Journal

Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179

Informations de publication

Date de publication:
13 06 2022
Historique:
received: 16 12 2021
accepted: 04 05 2022
entrez: 13 6 2022
pubmed: 14 6 2022
medline: 16 6 2022
Statut: epublish

Résumé

Reduced glomerular filtration rate (GFR) can progress to kidney failure. Risk factors include genetics and diabetes mellitus (DM), but little is known about their interaction. We conducted genome-wide association meta-analyses for estimated GFR based on serum creatinine (eGFR), separately for individuals with or without DM (n

Identifiants

DOI: 10.1038/s42003-022-03448-z PMID: 35697829 PMC: PMC9192715
pubmed: 35697829
doi: 10.1038/s42003-022-03448-z
pii: 10.1038/s42003-022-03448-z
pmc: PMC9192715
doi:

Substances chimiques

Creatinine AYI8EX34EU

Types de publication

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

580

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK093757
Pays : United States
Organisme : Medical Research Council
ID : MC_PC_17228
Pays : United Kingdom
Organisme : NIDDK NIH HHS
ID : R01 DK072193
Pays : United States
Organisme : CSRD VA
ID : I01 CX001897
Pays : United States
Organisme : Medical Research Council
ID : G0700931
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R023484/1
Pays : United Kingdom
Organisme : NIEHS NIH HHS
ID : P30 ES030285
Pays : United States
Organisme : Medical Research Council
ID : MR/L01632X/1
Pays : United Kingdom
Organisme : NIDDK NIH HHS
ID : P30 DK020572
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK062370
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL105756
Pays : United States
Organisme : CSRD VA
ID : I01 CX001737
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK020541
Pays : United States
Organisme : NIA NIH HHS
ID : U19 AG063893
Pays : United States
Organisme : Medical Research Council
ID : G0601966
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_00007/10
Pays : United Kingdom
Organisme : NIDDK NIH HHS
ID : U01 DK062370
Pays : United States
Organisme : BLRD VA
ID : I01 BX005831
Pays : United States
Organisme : Medical Research Council
ID : MR/S019669/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_QA137853
Pays : United Kingdom
Organisme : NIDDK NIH HHS
ID : L30 DK065708
Pays : United States

Investigateurs

Chris H L Thio (CHL)
Peter J van der Most (PJ)
Martin H de Borst (MH)
Kevin Ho (K)
Navya Shilpa Josyula (NS)
Sarah A Pendergrass (SA)
Bryce X Rowan (BX)
Cassianne Robinson-Cohen (C)
John M Gaziano (JM)
Lawrence S Phillips (LS)
Ran Tao (R)
Adriana M Hung (AM)

Informations de copyright

© 2022. The Author(s).

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Auteurs

Thomas W Winkler (TW)

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany. thomas.winkler@ukr.de.
ORCID: 0000-0003-0292-5421

Humaira Rasheed (H)

K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Division of Medicine and Laboratory Sciences, University of Oslo, Oslo, Norway.
ORCID: 0000-0002-3331-5864

Alexander Teumer (A)

Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.
ORCID: 0000-0002-8309-094X

Mathias Gorski (M)

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.

Bryce X Rowan (BX)

Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.

Kira J Stanzick (KJ)

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.

Laurent F Thomas (LF)

K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Department of Clinical and Molecular Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
BioCore-Bioinformatics Core Facility, Norwegian University of Science and Technology, Trondheim, Norway.

Adrienne Tin (A)

Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
ORCID: 0000-0002-4207-5866

Anselm Hoppmann (A)

Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.

Audrey Y Chu (AY)

Genetics, Merck & Co., Inc, Kenilworth, NJ, USA.

Bamidele Tayo (B)

Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA.

Chris H L Thio (CHL)

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Daniele Cusi (D)

Institute of Biomedical Technologies, National Research Council of Italy, Milan, Italy.
Bio4Dreams-Business Nursery for Life Sciences, Milan, Italy.

Jin-Fang Chai (JF)

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.

Karsten B Sieber (KB)

Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA.

Katrin Horn (K)

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.

Man Li (M)

Division of Nephrology and Hypertension, Department of Medicine, University of Utah, Salt Lake City, UT, USA.

Markus Scholz (M)

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.

Massimiliano Cocca (M)

Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
ORCID: 0000-0002-1127-7596

Matthias Wuttke (M)

Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
Renal Division, Department of Medicine IV, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.

Peter J van der Most (PJ)

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
ORCID: 0000-0001-8450-3518

Qiong Yang (Q)

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
ORCID: 0000-0002-3658-1375

Sahar Ghasemi (S)

Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.

Teresa Nutile (T)

Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy.

Yong Li (Y)

Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
ORCID: 0000-0003-2651-8791

Giulia Pontali (G)

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
University of Trento, Department of Cellular, Computational and Integrative Biology-CIBIO, Trento, Italy.
ORCID: 0000-0002-4521-8981

Felix Günther (F)

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
Statistical Consulting Unit StaBLab, Department of Statistics, LMU Munich, Munich, Germany.

Abbas Dehghan (A)

MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Dementia Research Institute, Imperial College London, London, UK.
ORCID: 0000-0001-6403-016X

Adolfo Correa (A)

Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.

Afshin Parsa (A)

Division of Kidney, Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
University of Maryland School of Medicine, Baltimore, MD, USA.

Agnese Feresin (A)

Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

Aiko P J de Vries (APJ)

Section of Nephrology, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.

Alan B Zonderman (AB)

Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Baltimore, MD, USA.

Albert V Smith (AV)

Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France.
ORCID: 0000-0003-1942-5845

Albertine J Oldehinkel (AJ)

Interdisciplinary Center of Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Alessandro De Grandi (A)

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

Alexander R Rosenkranz (AR)

Department of Internal Medicine, Division of Nephrology, Medical University Graz, Graz, Austria.

Andre Franke (A)

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
ORCID: 0000-0003-1530-5811

Andrej Teren (A)

LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Heart Center Leipzig, Leipzig, Germany.

Andres Metspalu (A)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
ORCID: 0000-0002-3718-796X

Andrew A Hicks (AA)

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
ORCID: 0000-0001-6320-0411

Andrew P Morris (AP)

Department of Health Data Science, University of Liverpool, Liverpool, UK.
Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.

Anke Tönjes (A)

Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.

Anna Morgan (A)

Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.

Anna I Podgornaia (AI)

Genetics, Merck & Co., Inc, Kenilworth, NJ, USA.

Annette Peters (A)

Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
German Center for Diabetes Research (DZD), Neuherberg, Germany.
Chair of Epidemiology, IBE, Faculty of Medicine, Ludwig-Maximilians-Universität München, München, Germany.

Antje Körner (A)

LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.
Center for Pediatric Research, University of Leipzig, Leipzig, Germany.

Anubha Mahajan (A)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.

Archie Campbell (A)

Center for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.

Barry I Freedman (BI)

Section on Nephrology, Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
ORCID: 0000-0003-0275-5530

Beatrice Spedicati (B)

Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
ORCID: 0000-0002-7432-4708

Belen Ponte (B)

Service de Néphrologie et Hypertension, Medicine Department, Geneva University Hospitals, Geneva, Switzerland.

Ben Schöttker (B)

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Network Aging Research, University of Heidelberg, Heidelberg, Germany.

Ben Brumpton (B)

K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, 7030, Norway.
HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, 7600, Norway.
ORCID: 0000-0002-3058-1059

Bernhard Banas (B)

Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.

Bernhard K Krämer (BK)

Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology, Pneumology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Bettina Jung (B)

Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.
Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
Department of Nephrology and Rheumatology, Kliniken Südostbayern, Traunstein, Germany.

Bjørn Olav Åsvold (BO)

K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Department of Endocrinology, Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
ORCID: 0000-0003-3837-2101

Blair H Smith (BH)

Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
ORCID: 0000-0002-5362-9430

Boting Ning (B)

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

Brenda W J H Penninx (BWJH)

Department of Psychiatry, VU University Medical Centre, Amsterdam, The Netherlands.

Brett R Vanderwerff (BR)

Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.

Bruce M Psaty (BM)

Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Department of Epidemiology, University of Washington, Seattle, WA, USA.
Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA.
ORCID: 0000-0002-7278-2190

Candace M Kammerer (CM)

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.

Carl D Langefeld (CD)

Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.
ORCID: 0000-0002-4266-6949

Caroline Hayward (C)

Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0002-9405-9550

Cassandra N Spracklen (CN)

Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Department of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, MA, USA.
ORCID: 0000-0003-3590-7182

Cassianne Robinson-Cohen (C)

Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.
Vanderbilt University Medical Center, Division of Nephrology and Hypertension, Vanderbilt Center for Kidney Disease and Integrated Program for Acute Kidney Injury Research, and Vanderbilt Precision Nephrology Program Nashville, Nashville, TN, USA.

Catharina A Hartman (CA)

Interdisciplinary Center of Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Cecilia M Lindgren (CM)

Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, OX3 7LF, UK.

Chaolong Wang (C)

Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
ORCID: 0000-0003-3945-1012

Charumathi Sabanayagam (C)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
ORCID: 0000-0002-4042-4719

Chew-Kiat Heng (CK)

Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
ORCID: 0000-0002-7309-9473

Chiara Lanzani (C)

Nephrology and Dialysis Unit, Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Chiea-Chuen Khor (CC)

Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
ORCID: 0000-0002-1128-4729

Ching-Yu Cheng (CY)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
ORCID: 0000-0003-0655-885X

Christian Fuchsberger (C)

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

Christian Gieger (C)

Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
German Center for Diabetes Research (DZD), Neuherberg, Germany.
Research Unit Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
ORCID: 0000-0001-6986-9554

Christian M Shaffer (CM)

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.

Christina-Alexandra Schulz (CA)

Department of Clincial Sciences in Malmö, Lund University, Malmö, Sweden.

Cristen J Willer (CJ)

Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA.
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.
Department of Human Genetics, University of Michigan, Ann Arbor, MI, 48109, USA.
ORCID: 0000-0001-5645-4966

Daniel I Chasman (DI)

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.

Daniel F Gudbjartsson (DF)

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
Iceland School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.

Daniela Ruggiero (D)

Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy.
IRCCS Neuromed, Pozzilli, Italy.

Daniela Toniolo (D)

San Raffaele Research Institute, Milan, Italy.

Darina Czamara (D)

Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
ORCID: 0000-0001-7381-904X

David J Porteous (DJ)

Center for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Center for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0003-1249-6106

Dawn M Waterworth (DM)

Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA.

Deborah Mascalzoni (D)

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
Centre for Research Ethics & Bioethics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
ORCID: 0000-0003-4156-1464

Dennis O Mook-Kanamori (DO)

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

Dermot F Reilly (DF)

Genetics, Merck & Co., Inc, Kenilworth, NJ, USA.

E Warwick Daw (EW)

Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.

Edith Hofer (E)

Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.
Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.

Eric Boerwinkle (E)

Human Genetics Center, University of Texas Health Science Center, Houston, TX, USA.

Erika Salvi (E)

Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Milan, Italy.

Erwin P Bottinger (EP)

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Digital Health Center, Hasso Plattner Institute and University of Potsdam, Potsdam, Germany.

E-Shyong Tai (ES)

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
Duke - NUS Medical School, Singapore, Singapore.
ORCID: 0000-0003-2929-8966

Eulalia Catamo (E)

Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.

Federica Rizzi (F)

Bio4Dreams-Business Nursery for Life Sciences, Milan, Italy.
ePhood Scientific Unit, ePhood SRL, Milano, Italy.
ORCID: 0000-0002-4606-6553

Feng Guo (F)

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Fernando Rivadeneira (F)

Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
ORCID: 0000-0001-9435-9441

Franco Guilianini (F)

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Gardar Sveinbjornsson (G)

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

Georg Ehret (G)

Cardiology, Geneva University Hospitals, Geneva, Switzerland.

Gerard Waeber (G)

Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Ginevra Biino (G)

Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza", National Research Council of Italy, Pavia, Italy.

Giorgia Girotto (G)

Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

Giorgio Pistis (G)

Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland.

Girish N Nadkarni (GN)

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Graciela E Delgado (GE)

Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Grant W Montgomery (GW)

Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD, Australia.
ORCID: 0000-0002-4140-8139

Harold Snieder (H)

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
ORCID: 0000-0003-1949-2298

Harry Campbell (H)

Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.

Harvey D White (HD)

Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand.

He Gao (H)

MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.

Heather M Stringham (HM)

Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
ORCID: 0000-0002-2991-6392

Helena Schmidt (H)

Research Unit Genetic Epidemiology, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
ORCID: 0000-0001-9773-9992

Hengtong Li (H)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.

Hermann Brenner (H)

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Network Aging Research, University of Heidelberg, Heidelberg, Germany.

Hilma Holm (H)

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
ORCID: 0000-0002-9517-6636

Holgen Kirsten (H)

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.

Holly Kramer (H)

Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA.
Division of Nephrology and Hypertension, Loyola University Chicago, Chicago, IL, USA.

Igor Rudan (I)

Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.

Ilja M Nolte (IM)

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Ioanna Tzoulaki (I)

MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Dementia Research Institute, Imperial College London, London, UK.
Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.

Isleifur Olafsson (I)

Department of Clinical Biochemistry, Landspitali University Hospital, Reykjavik, Iceland.

Jade Martins (J)

Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
ORCID: 0000-0001-6528-8947

James P Cook (JP)

Department of Health Data Science, University of Liverpool, Liverpool, UK.

James F Wilson (JF)

Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0001-5751-9178

Jan Halbritter (J)

Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Janine F Felix (JF)

Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
ORCID: 0000-0002-9801-5774

Jasmin Divers (J)

Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Jaspal S Kooner (JS)

Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UK.
Imperial College Healthcare NHS Trust, Imperial College London, London, UK.
MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK.
National Heart and Lung Institute, Imperial College London, London, UK.
ORCID: 0000-0003-2086-4837

Jeannette Jen-Mai Lee (JJ)

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.

Jeffrey O'Connell (J)

University of Maryland School of Medicine, Baltimore, MD, USA.

Jerome I Rotter (JI)

The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institutefor Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.

Jianjun Liu (J)

Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
ORCID: 0000-0002-3255-3019

Jie Xu (J)

Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Joachim Thiery (J)

LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.

Johan Ärnlöv (J)

Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
School of Health and Social Studies, Dalarna University, Stockholm, Sweden.

Johanna Kuusisto (J)

University of Eastern Finland, Kuopio, Finland.
Kuopio University Hospital, Kuopio, Finland.

Johanna Jakobsdottir (J)

Icelandic Heart Association, Kopavogur, Iceland.
The Center of Public Health Sciences, University of Iceland, Reykjavík, Iceland.

Johanne Tremblay (J)

Montreal University Hospital Research Center, CHUM, Montreal, QC, Canada.
CRCHUM, Montreal, QC, Canada.

John C Chambers (JC)

MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UK.
Imperial College Healthcare NHS Trust, Imperial College London, London, UK.
MRC-PHE Center for Environment and Health, School of Public Health, Imperial College London, London, UK.
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.

John B Whitfield (JB)

QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.

John M Gaziano (JM)

Department of Internal Medicine, Harvard Medical School, Boston, MA, USA.
VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA.

Jonathan Marten (J)

Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.

Josef Coresh (J)

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
ORCID: 0000-0002-4598-0669

Jost B Jonas (JB)

Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany.
Instituteof Molecular and Clinical Ophthalmology, Basel, Switzerland.
Privatpraxis Prof Jonas und Dr Panda-Jonas, Heidelberg, Germany.
ORCID: 0000-0003-2972-5227

Josyf C Mychaleckyj (JC)

Center for Public Health Genomics, University of Virginia, Charlottesville, Charlottesville, VA, USA.
ORCID: 0000-0003-2595-0005

Kaare Christensen (K)

Danish Aging Research Center, University of Southern Denmark, Odense C, Denmark.
ORCID: 0000-0002-5429-5292

Kai-Uwe Eckardt (KU)

Intensive Care Medicine, Charité, Berlin, Germany.
Department of Nephrology and Hypertension, Friedrich Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.

Karen L Mohlke (KL)

Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
ORCID: 0000-0001-6721-153X

Karlhans Endlich (K)

DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Department of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.

Katalin Dittrich (K)

Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.
Center for Pediatric Research, University of Leipzig, Leipzig, Germany.

Kathleen A Ryan (KA)

Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.
ORCID: 0000-0003-1158-8455

Kenneth M Rice (KM)

Department of Biostatistics, University of Washington, Seattle, WA, USA.
ORCID: 0000-0002-3071-7278

Kent D Taylor (KD)

The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institutefor Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.

Kevin Ho (K)

Geisinger Research, Biomedical and Translational Informatics Institute, Rockville, MD, USA.
Department of Nephrology, Geisinger, Danville, PA, USA.

Kjell Nikus (K)

Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, Finland.
Department of Cardiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Koichi Matsuda (K)

Laboratory of Clinical Genome Sequencing, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.

Konstantin Strauch (K)

Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Chair of Genetic Epidemiology, IBE, Faculty of Medicine, Ludwig-Maximilians-Universität München, München, Germany.
Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.

Kozeta Miliku (K)

Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Kristian Hveem (K)

K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.

Lars Lind (L)

Cardiovascular Epidemiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

Lars Wallentin (L)

Cardiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.

Laura M Yerges-Armstrong (LM)

Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA.
ORCID: 0000-0003-0006-5237

Laura M Raffield (LM)

Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
ORCID: 0000-0002-7892-193X

Lawrence S Phillips (LS)

Atlanta VA Health Care System, Decatur, GA, USA.
Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.

Lenore J Launer (LJ)

Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, MD, USA.
ORCID: 0000-0002-3238-7612

Leo-Pekka Lyytikäinen (LP)

Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Leslie A Lange (LA)

Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO, USA.

Lorena Citterio (L)

Nephrology and Dialysis Unit, Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Lucija Klaric (L)

Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.

M Arfan Ikram (MA)

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
ORCID: 0000-0003-0372-8585

Marcus Ising (M)

Max Planck Institute of Psychiatry, Munich, Germany.

Marcus E Kleber (ME)

Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
SYNLAB MVZ Humangenetik Mannheim, Mannheim, Germany.

Margherita Francescatto (M)

Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

Maria Pina Concas (MP)

Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.

Marina Ciullo (M)

Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy.
IRCCS Neuromed, Pozzilli, Italy.

Mario Piratsu (M)

Institute of Genetic and Biomedical Research, National Research Council of Italy, Cagliari, Italy.

Marju Orho-Melander (M)

Department of Clincial Sciences in Malmö, Lund University, Malmö, Sweden.

Markku Laakso (M)

University of Eastern Finland, Kuopio, Finland.
Kuopio University Hospital, Kuopio, Finland.
ORCID: 0000-0002-3394-7749

Markus Loeffler (M)

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.

Markus Perola (M)

Finnish Institute for Health and Welfare, Helsinki, Finland.
Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Martin H de Borst (MH)

Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
ORCID: 0000-0002-4127-8733

Martin Gögele (M)

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
ORCID: 0000-0003-4785-4348

Martina La Bianca (M)

Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.

Mary Ann Lukas (MA)

Target Sciences-Genetics, GlaxoSmithKline, Albuquerque, NM, USA.

Mary F Feitosa (MF)

Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.

Mary L Biggs (ML)

Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Department of Biostatistics, University of Washington, Seattle, WA, USA.

Mary K Wojczynski (MK)

Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
ORCID: 0000-0002-2420-162X

Maryam Kavousi (M)

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Masahiro Kanai (M)

Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
ORCID: 0000-0001-5165-4408

Masato Akiyama (M)

Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Masayuki Yasuda (M)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan.

Matthias Nauck (M)

DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.

Melanie Waldenberger (M)

Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Research Unit Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
ORCID: 0000-0003-0583-5093

Miao-Li Chee (ML)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.

Miao-Ling Chee (ML)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.

Michael Boehnke (M)

Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
ORCID: 0000-0002-6442-7754

Michael H Preuss (MH)

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
ORCID: 0000-0001-5266-8465

Michael Stumvoll (M)

Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
ORCID: 0000-0001-6225-8240

Michael A Province (MA)

Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.

Michele K Evans (MK)

Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Baltimore, MD, USA.

Michelle L O'Donoghue (ML)

Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA.
TIMI Study Group, Boston, MA, USA.

Michiaki Kubo (M)

RIKEN Center for Integrative Medical Sciences (IMS), Yokohama (Kanagawa), Japan.
ORCID: 0000-0002-0095-2322

Mika Kähönen (M)

Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.
Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Mika Kastarinen (M)

Kuopio University Hospital, Kuopio, Finland.

Mike A Nalls (MA)

Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Data Tecnica International, Glen Echo, MD, USA.

Mikko Kuokkanen (M)

Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
The Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
South Texas Diabetes and Obesity Institute and Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.

Mohsen Ghanbari (M)

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
ORCID: 0000-0002-9476-7143

Murielle Bochud (M)

Center for Primary Care and Public Health (Unisanté), University of Lausanne, 1010, Lausanne, Switzerland.

Navya Shilpa Josyula (NS)

Department of Population Health Sciences, Geisinger Health, 100 N. Academy Ave., Danville, PA, USA.
ORCID: 0000-0003-2782-8812

Nicholas G Martin (NG)

QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
ORCID: 0000-0003-4069-8020

Nicholas Y Q Tan (NYQ)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.

Nicholette D Palmer (ND)

Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Nicola Pirastu (N)

Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0002-5363-3886

Nicole Schupf (N)

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA.

Niek Verweij (N)

Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Nina Hutri-Kähönen (N)

Tampere Centre for Skills Training and Simulation, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Nina Mononen (N)

Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Nisha Bansal (N)

Division of Nephrology, University of Washington, Seattle, WA, USA.
Kidney Research Institute, University of Washington, Seattle, WA, USA.

Olivier Devuyst (O)

Institute of Physiology, University of Zurich, Zurich, Switzerland.

Olle Melander (O)

Department of Clincial Sciences in Malmö, Lund University, Malmö, Sweden.

Olli T Raitakari (OT)

Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.

Ozren Polasek (O)

Faculty of Medicine, University of Split, Split, Croatia.
Algebra University College, Ilica 242, Zagreb, Croatia.

Paolo Manunta (P)

Nephrology and Dialysis Unit, Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Paolo Gasparini (P)

Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

Pashupati P Mishra (PP)

Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Patrick Sulem (P)

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
ORCID: 0000-0001-7123-6123

Patrik K E Magnusson (PKE)

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Paul Elliott (P)

MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Dementia Research Institute, Imperial College London, London, UK.
Imperial College NIHR Biomedical Research Center, Imperial College London, London, UK.
Health Data Research UK-London, London, UK.

Paul M Ridker (PM)

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.

Pavel Hamet (P)

Montreal University Hospital Research Center, CHUM, Montreal, QC, Canada.
Medpharmgene, Montreal, QC, Canada.

Per O Svensson (PO)

Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.
Department of Cardiology, Södersjukhuset, Stockholm, Sweden.

Peter K Joshi (PK)

Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0002-6361-5059

Peter Kovacs (P)

Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Integrated Research and Treatment Center Adiposity Diseases, University of Leipzig, Leipzig, Germany.
ORCID: 0000-0002-0290-5423

Peter P Pramstaller (PP)

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

Peter Rossing (P)

Steno Diabetes Center Copenhagen, Herlev, Denmark.
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
ORCID: 0000-0002-1531-4294

Peter Vollenweider (P)

Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Pim van der Harst (P)

Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Rajkumar Dorajoo (R)

Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
ORCID: 0000-0001-6608-2051

Ralene Z H Sim (RZH)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.

Ralph Burkhardt (R)

LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.
Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.

Ran Tao (R)

Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.

Raymond Noordam (R)

Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
ORCID: 0000-0001-7801-809X

Reedik Mägi (R)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.

Reinhold Schmidt (R)

Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.

Renée de Mutsert (R)

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

Rico Rueedi (R)

Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Swiss Institute of Bioinformatics, Lausanne, Switzerland.

Rob M van Dam (RM)

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington, DC, USA.

Robert J Carroll (RJ)

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.

Ron T Gansevoort (RT)

Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Ruth J F Loos (RJF)

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Novo Nordisk Foundation Center for Basic Metabolic Research, Department of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
ORCID: 0000-0002-8532-5087

Sala Cinzia Felicita (SC)

San Raffaele Research Institute, Milan, Italy.

Sanaz Sedaghat (S)

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Sandosh Padmanabhan (S)

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

Sandra Freitag-Wolf (S)

Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, Kiel, Germany.

Sarah A Pendergrass (SA)

Geisinger Research, Biomedical and Translational Informatics Institute, Danville, PA, USA.

Sarah E Graham (SE)

Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA.
ORCID: 0000-0003-1271-2489

Scott D Gordon (SD)

QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
ORCID: 0000-0001-7623-328X

Shih-Jen Hwang (SJ)

NHLBI's Framingham Heart Study, Framingham, MA, USA.
The Center for Population Studies, NHLBI, Framingham, MA, USA.

Shona M Kerr (SM)

Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0002-4137-1495

Simona Vaccargiu (S)

Institute of Genetic and Biomedical Research, National Research Council of Italy, Cagliari, Italy.

Snehal B Patil (SB)

Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.

Stein Hallan (S)

Department of Clinical and Molecular Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Department of Nephrology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.

Stephan J L Bakker (SJL)

Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Su-Chi Lim (SC)

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Diabetes Center, Khoo Teck Puat Hospital, Singapore, Singapore.

Susanne Lucae (S)

Max Planck Institute of Psychiatry, Munich, Germany.

Suzanne Vogelezang (S)

Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Sven Bergmann (S)

Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Swiss Institute of Bioinformatics, Lausanne, Switzerland.
ORCID: 0000-0002-6785-9034

Tanguy Corre (T)

Center for Primary Care and Public Health (Unisanté), University of Lausanne, 1010, Lausanne, Switzerland.
Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Swiss Institute of Bioinformatics, Lausanne, Switzerland.

Tarunveer S Ahluwalia (TS)

Steno Diabetes Center Copenhagen, Herlev, Denmark.
The Bioinformatics Center, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
ORCID: 0000-0002-7464-3354

Terho Lehtimäki (T)

Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
ORCID: 0000-0002-2555-4427

Thibaud S Boutin (TS)

Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0003-4754-1675

Thomas Meitinger (T)

DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.
Institute of Human Genetics, Technische Universität München, Munich, Germany.

Tien-Yin Wong (TY)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.

Tobias Bergler (T)

Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.

Ton J Rabelink (TJ)

Section of Nephrology, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Einthoven Laboratory of Experimental Vascular Research, Leiden University Medical Center, Leiden, The Netherlands.
ORCID: 0000-0001-6780-5186

Tõnu Esko (T)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.

Toomas Haller (T)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.

Unnur Thorsteinsdottir (U)

Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

Uwe Völker (U)

DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
ORCID: 0000-0002-5689-3448

Valencia Hui Xian Foo (VHX)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.

Veikko Salomaa (V)

Finnish Institute for Health and Welfare, Helsinki, Finland.
ORCID: 0000-0001-7563-5324

Veronique Vitart (V)

Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0002-4991-3797

Vilmantas Giedraitis (V)

Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.

Vilmundur Gudnason (V)

Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Icelandic Heart Association, Kopavogur, Iceland.
ORCID: 0000-0001-5696-0084

Vincent W V Jaddoe (VWV)

Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
ORCID: 0000-0003-2939-0041

Wei Huang (W)

Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center, Shanghai, China.
Shanghai Industrial Technology Institute, Shanghai, China.

Weihua Zhang (W)

MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UK.
ORCID: 0000-0001-8279-3611

Wen Bin Wei (WB)

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Wieland Kiess (W)

LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Department of Women and Child Health, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.
Center for Pediatric Research, University of Leipzig, Leipzig, Germany.

Winfried März (W)

Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany.
Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.

Wolfgang Koenig (W)

DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.
Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany.
ORCID: 0000-0002-2064-9603

Wolfgang Lieb (W)

Institute of Epidemiology and Biobank Popgen, Kiel University, Kiel, Germany.
ORCID: 0000-0003-2544-4460

Xin Gao (X)

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Xueling Sim (X)

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
ORCID: 0000-0002-1233-7642

Ya Xing Wang (YX)

Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
ORCID: 0000-0003-2749-7793

Yechiel Friedlander (Y)

School of Public Health and Community Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Yih-Chung Tham (YC)

Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
ORCID: 0000-0002-6752-797X

Yoichiro Kamatani (Y)

Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.
ORCID: 0000-0001-8748-5597

Yukinori Okada (Y)

Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences (IMS), Osaka, Japan.
Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.
ORCID: 0000-0002-0311-8472

Yuri Milaneschi (Y)

Department of Psychiatry, VU University Medical Centre, Amsterdam, The Netherlands.

Zhi Yu (Z)

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Massachusetts General Hospital, Boston, MA, USA.
ORCID: 0000-0003-4810-3474

Klaus J Stark (KJ)

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.

Kari Stefansson (K)

Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
ORCID: 0000-0003-1676-864X

Carsten A Böger (CA)

Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.
Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
Department of Nephrology and Rheumatology, Kliniken Südostbayern, Traunstein, Germany.

Adriana M Hung (AM)

Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.
Vanderbilt University Medical Center, Division of Nephrology and Hypertension, Vanderbilt Center for Kidney Disease and Integrated Program for Acute Kidney Injury Research, and Vanderbilt Precision Nephrology Program Nashville, Nashville, TN, USA.

Florian Kronenberg (F)

Department of Genetics and Pharmacology, Institute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria.
ORCID: 0000-0003-2229-1120

Anna Köttgen (A)

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
ORCID: 0000-0002-4671-3714

Cristian Pattaro (C)

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
ORCID: 0000-0002-4119-0109

Iris M Heid (IM)

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany. iris.heid@ukr.de.
ORCID: 0000-0002-4122-5308

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Imidazoles › Créatinine › Differential and shared genetic effects on...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Differential and shared genetic effects on...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Complications du diabète › Néphropathies diabétiques › Differential and shared genetic effects on...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Épidémiologie moléculaire › Étude d'association pangénomique › Differential and shared genetic effects on...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques des voies urinaires › Débit de filtration glomérulaire › Differential and shared genetic effects on...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Differential and shared genetic effects on...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Differential and shared genetic effects on...