Prevalence of Y chromosome microdeletions among infertile Mongolian men.
Azoospermia
Infertility
Semen analysis
Y chromosome
Journal
Clinical and experimental reproductive medicine
ISSN: 2233-8233
Titre abrégé: Clin Exp Reprod Med
Pays: Korea (South)
ID NLM: 101563916
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
15
11
2021
accepted:
06
01
2022
entrez:
14
6
2022
pubmed:
15
6
2022
medline:
15
6
2022
Statut:
ppublish
Résumé
Y chromosome microdeletions are the second most common genetic cause of male infertility after Klinefelter syndrome. The aim of this study was to determine the patterns of Y chromosome microdeletions among infertile Mongolian men. A descriptive study was performed on 75 infertile men from February 2017 to December 2018. Y chromosome microdeletions were identified by polymerase chain reaction. Semen parameters, hormonal levels, and testis biopsy samples were examined. Among 75 infertile men, two cases of Y chromosome microdeletions were identified. The first case had an AZFa complete deletion and the other had an AZFc partial deletion. This study found that the proportion of Y chromosome microdeletions among infertile Mongolian men was 2.66%. The findings can be applied to in vitro fertilization and assisted reproductive technology, and our results will help clinicians improve treatment management for infertile Mongolian couples.
Identifiants
pubmed: 35698772
pii: cerm.2021.05099
doi: 10.5653/cerm.2021.05099
pmc: PMC9184878
doi:
Types de publication
Journal Article
Langues
eng
Pagination
101-109Références
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