Cardiac Sarcoidosis Diagnostic Challenges and Management: A Case Report and Literature Review.

arrhythmia atrioventricular conduction abnormality cardiac manifestations cardiac sudden death case report extrapulmonary sarcoidosis heart failure

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
May 2022
Historique:
received: 27 03 2022
accepted: 08 05 2022
entrez: 15 6 2022
pubmed: 16 6 2022
medline: 16 6 2022
Statut: epublish

Résumé

Sarcoidosis can be presented as cardiac sarcoidosis (CS), which is challenging to diagnose due to its clinical silence. Ventricular arrhythmias and atrioventricular blocks can be fatal and cause sudden death in patients with cardiac sarcoidosis. Five percent of sarcoidosis patients have clinically evident cardiac sarcoidosis. However, autopsy reports and imaging studies have shown a higher prevalence of cardiac involvement. Early recognition is important to prevent such detrimental consequences. Cardiac sarcoidosis is increasingly being diagnosed owing to increased awareness among physicians and new diagnostic tools like MRI and positron emission tomography (PET) scan replacing traditional endomyocardial biopsy. A definitive diagnosis of CS remains challenging due to the non-specific clinical findings that can present similar symptoms of common cardiac disease; therefore, the imaging and biopsies are substantial for diagnosis confirmation. Pharmacological and Implantable devices are two main therapeutic approaches in cardiac sarcoidosis, in which steroids and pacemaker therapy have shown better outcomes. This review summarizes the available data related to the prevalence, prognosis, diagnosis, and management of cardiac sarcoidosis.

Identifiants

pubmed: 35702472
doi: 10.7759/cureus.24850
pmc: PMC9177213
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e24850

Informations de copyright

Copyright © 2022, Jaiswal et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Richa Jaiswal (R)

Internal Medicine, Medical University of South Carolina, Charleston, USA.

Laseena Vaisyambath (L)

Pathology, Markham Stouffville Hospital, Markham, CAN.

Azadeh Khayyat (A)

Pathology and Laboratory Medicine, Brown University, Providence, USA.

Nkechinyere Unachukwu (N)

Internal Medicine, Interfaith Medical Center, New York, USA.

Bibimariyam Nasyrlaeva (B)

Pathology and Laboratory Medicine, siParadigm Diagnostic Informatics, Pine Brook, USA.

Muhammad Asad (M)

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, USA.

Stephanie P Fabara (SP)

General Medicine, Universidad Catolica de Santiago de Guayaquil, Guayaquil, ECU.

Irina Balan (I)

Internal Medicine, Nicolae Testemițanu State University of Medicine and Pharmacy, Chisinau, MDA.

Sree Kolla (S)

Biological Sciences, Staten Island Technical High School, Staten Island, USA.

Rizwan Rabbani (R)

Internal Medicine, Temple University Hospital, Philadelphia, USA.

Classifications MeSH