Limbic Stimulation Drives Mania in STN-DBS in Parkinson Disease: A Prospective Study.
Journal
Annals of neurology
ISSN: 1531-8249
Titre abrégé: Ann Neurol
Pays: United States
ID NLM: 7707449
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
revised:
30
05
2022
received:
24
01
2022
accepted:
05
06
2022
pubmed:
16
6
2022
medline:
23
8
2022
entrez:
15
6
2022
Statut:
ppublish
Résumé
In this one-year prospective study, Parkinson's disease (PD) patients with or without mania following STN-DBS were compared to investigate risk and etiological factors, clinical management and consequences. Eighteen (16.2%) out of 111 consecutive PD patients developed mania, of whom 17 were males. No preoperative risk factor was identified. Postoperative mania was related to ventral limbic subthalamic stimulation in 15 (83%) patients, and resolved as stimulation was relocated to the sensorimotor STN, besides discontinuation or reduction of dopamine agonists and use of low-dose clozapine in 12 patients, while motor and nonmotor outcomes were similar. These findings underpin the prominent role of limbic subthalamic stimulation in postoperative mania. ANN NEUROL 2022;92:411-417.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
411-417Investigateurs
Caroline Moreau
(C)
Luc Defebvre
(L)
Nicolas Carriere
(N)
Guillaume Grolez
(G)
Gillaume Baille
(G)
None Kreisler
Jean-Pierre Pruvo
(JP)
None Leclerc
Renaud Lopes
(R)
Romain Viard
(R)
Gregory Kuchcinski
(G)
Julien Dumont
(J)
Kathy Dujardin
(K)
M Delliaux
(M)
M Brion
(M)
Gustavo Touzet
(G)
Nicolas Reyns
(N)
Arnaud Delval
(A)
Valerie Santraine
(V)
Marie Pleuvret
(M)
Nolwen Dautrevaux
(N)
Victor Laugeais
(V)
Morgane Coeffet
(M)
Thavarak Ouk
(T)
Camille Potey
(C)
Celine Leclercq
(C)
Elise Gers
(E)
Jean-Christophe Corvol
(JC)
Marie Vidailhet
(M)
Elodie Hainque
(E)
Marie-Laure Welter
(ML)
Lucette Lacomblez
(L)
David Grabli
(D)
Emmanuel Roze
(E)
Yulia Worbe
(Y)
Cécile Delorme
(C)
Hana You
(H)
Jonas Ihle
(J)
Raquel Guimeraes-Costa
(R)
Florence Cormier-Dequaire
(F)
Aurélie Méneret
(A)
Andréas Hartmann
(A)
Louise-Laure Mariani
(LL)
Stéphane Lehericy
(S)
Virginie Czernecki
(V)
Fanny Pineau
(F)
Frédérique Bozon
(F)
Camille Huiban
(C)
Eve Benchetrit
(E)
Carine Karachi
(C)
Soledad Navarro
(S)
Philippe Cornu
(P)
Arlette Welaratne
(A)
Carole Dongmo-Kenfack
(C)
Lise Mantisi
(L)
Nathalie Jarry
(N)
Sophie Aix
(S)
Carine Lefort
(C)
Tiphaine Rouaud
(T)
Philippe Damier
(P)
Pascal Derkinderen
(P)
Anne-Gaelle Corbille
(AG)
Elisabeth Calvier-Auffray
(E)
Madame Laetitia Rocher
(ML)
Madame Anne-Laure Deruet
(MA)
Raoul Sylvie
(R)
Roualdes Vincent
(R)
Le Dily Séverine
(LD)
Ana Marques
(A)
Berangere Debilly
(B)
Franck Durif
(F)
Philippe Derost
(P)
Charlotte Beal
(C)
Carine Chassain
(C)
Laure Delaby
(L)
Tiphaine Vidal
(T)
Jean Jacques Lemaire
(JJ)
Isabelle Rieu
(I)
Elodie Durand
(E)
Alexandre Eusebio
(A)
Jean-Philippe Azulay
(JP)
Tatiana Witjas
(T)
Frédérique Fluchère
(F)
Stephan Grimaldi
(S)
Nadine Girard
(N)
Eve Benchetrit
(E)
Marie Delfini
(M)
Romain Carron
(R)
Jean Regis
(J)
Giorgio Spatola
(G)
Camille Magnaudet
(C)
Ansquer Solène
(A)
Benatru Isabelle
(B)
Colin Olivier
(C)
J L Houeto
(JL)
Guillevin Remy
(G)
Fradet Anne
(F)
Anziza Manssouri
(A)
Blondeau Sophie
(B)
Richard Philippe
(R)
Cam Philippe
(C)
Page Philippe
(P)
Bataille Benoit
(B)
Rabois Emilie
(R)
Guillemain Annie
(G)
Drapier Sophie
(D)
Frédérique Leh
(F)
Alexandre Bonnet
(A)
Marc Vérin
(M)
Jean-Christophe Ferré
(JC)
Jean François Houvenaghel
(JF)
Claire Haegelen
(C)
Francoise Kestens
(F)
Solenn Ory
(S)
Pierre Burbaud
(P)
Nathalie Damon-Perriere
(N)
Wassilios Meissner
(W)
Francois Tison
(F)
Stéphanie Bannier
(S)
Elsa Krim
(E)
Dominique Guehl
(D)
Sandrine Molinier-Blossier
(S)
Morgan Ollivier
(M)
Marion Lacoste
(M)
Nicolas Auzou
(N)
Marie Bonnet
(M)
Emmanuel Cuny
(E)
Julien Engelhardt
(J)
Olivier Branchard
(O)
Clotilde Huet
(C)
Julie Blanchard
(J)
Rascol Olivier
(R)
Christine Brefel Courbon
(CB)
Fabienne Ory Magne
(FO)
Marion Simonetta Moreau
(MS)
Christophe Arbus
(C)
Fabrice Bonneville
(F)
Jean Albert Lotterie
(JA)
Marion Sarrail
(M)
Patrick Chaynes
(P)
François Caire
(F)
Estelle Harroch
(E)
David Maltete
(D)
Romain Lefaucheur
(R)
Damien Fetter
(D)
Nicolas Magne
(N)
Sandrine Bioux
(S)
Maud Loubeyre
(M)
Evangéline Bliaux
(E)
Dorothée Pouliquen
(D)
Stéphane Derrey
(S)
Linda Vernon
(L)
Frédéric Ziegler
(F)
Mathieu Anheim
(M)
Ouhaid Lagha-Boukbiza
(O)
Christine Tranchant
(C)
Odile Gebus
(O)
Solveig Montaut
(S)
Stéphane Kremer
(S)
Nadine Longato
(N)
Clélie Phillips
(C)
Jimmy Voirin
(J)
Marie des Neiges Santin
(M)
Dominique Chaussemy
(D)
Amaury Mengin
(A)
Caroline Girodana
(C)
Claire Marsé
(C)
Lydiane Mondot
(L)
Bruno Giordana
(B)
Robin Kardous
(R)
Bernadette Bailet
(B)
Héloise Joly
(H)
Denys Fontaine
(D)
Aurélie Leplus
(A)
Amélie Faustini
(A)
Vanessa Ferrier
(V)
Pierre Krystkowiak
(P)
Mélissa Tir
(M)
Jean-Marc Constans
(JM)
Sandrine Wannepain
(S)
Audrey Seling
(A)
Michel Lefranc
(M)
Stéphanie Blin
(S)
Béatrice Schuler
(B)
Stephane Thobois
(S)
Teodor Danaila
(T)
Chloe Laurencin
(C)
Yves Berthezene
(Y)
Roxana Ameli
(R)
Helene Klinger
(H)
Gustavo Polo
(G)
Patrick Mertens
(P)
A Nunes
(A)
Elise Metereau
(E)
Lucie Hopes
(L)
Solène Frismand
(S)
Emmanuelle Schmitt
(E)
Mylène Meyer
(M)
Céline Dillier
(C)
Sophie Colnat
(S)
Anne Chatelain
(A)
Jean-Philippe Brandel
(JP)
Cécile Hubsch
(C)
Patte Karsenti
(P)
Marie Lebouteux
(M)
Marc Ziegler
(M)
Christine Delmaire
(C)
Julien Savatowky
(J)
Juliette Vrillac
(J)
Claire Nakache
(C)
Vincent D'Hardemare
(V)
Lhaouas Belamri
(L)
Frédérique Bourdain
(F)
Vadim Afanassiev
(V)
Philippe Graveleau
(P)
Cécilia Bonnet
(C)
Valérie Mesnage
(V)
Jarbas Correa Lino Junior
(JCL)
Camille Decrocq
(C)
Anne Boulin
(A)
Elodie Dupuy
(E)
Inès Barre
(I)
Bérénice Gardel
(B)
Béchir Jarraya
(B)
Delphine Lopez
(D)
Christophe Fruit
(C)
Catherine Ziz
(C)
David Gay
(D)
Robin Bonicel
(R)
Fouzia El Mountassir
(F)
Clara Fischer
(C)
Jean-François Mangin
(JF)
Marie Chupin
(M)
Yann Cointepas
(Y)
Bertrand Accart
(B)
Patrick Gelé
(P)
Florine Fievet
(F)
Matthieu Chabel
(M)
Virginie Derenaucourt
(V)
Loïc Facon
(L)
Yanick Tchantchou Njosse
(YT)
Dominique Deplanque
(D)
Alain Duhamel
(A)
Lynda Djemmane
(L)
Florence Duflot
(F)
Informations de copyright
© 2022 The Authors. Annals of Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association.
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