Long-Lasting Efficacy of Radio Electric Asymmetric Conveyer Neuromodulation Treatment on Functional Dysmetria, an Adaptive Motor Behavior.

endogenous bioelectric activity epigenetic functional dysmetria neurobiological modulation neuromodulation neuroplasticity neurostimulation neurotransmission radio electric asymmetric conveyor

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Jun 2022
Historique:
accepted: 08 06 2022
entrez: 16 6 2022
pubmed: 17 6 2022
medline: 17 6 2022
Statut: epublish

Résumé

Background Fluctuating asymmetry (FA) is widely defined as the deviation from perfect bilateral symmetry and is considered an epigenetic measure of environmental stress. Rinaldi and Fontani hypothesized that the FA morpho-functional changes originate from an adaptive motor behavior determined by functional alterations in the cerebellum and neural circuits, not caused by a lesion, but induced by environmental stress. They called this phenomenon functional dysmetria (FD). On this premise, they developed the radio electric asymmetric conveyer (REAC) technology, a neuromodulation technology aimed at optimizing the best neuro-psycho-motor strategies in relation to environmental interaction. Aims Previous studies showed that specific REAC neuro postural optimization (NPO) treatment can induce stable FD recovery. This study aimed to verify the duration of the NPO effect in inducing the stable FD recovery over time. Materials and methods Data were retrospectively collected from a population of 29,794 subjects who underwent a specific semiological FD assessment and received the NPO treatment, regardless of the pathology referred. Results The analysis of the data collected by the various participants in the study led us to ascertain the disappearance of FD in 100% of the cases treated, with a stability of the result detected up to 18 years after the single administration of the REAC NPO treatment. Conclusions The REAC NPO neurobiological modulation treatment consisting of a single administration surprisingly maintains a very long efficacy in the correction of FD. This effect can be explained as the long-lasting capacity of the NPO treatment to induce greater functional efficiency of the brain dynamics as proven in previous studies.

Identifiants

pubmed: 35706441
doi: 10.7759/cureus.25768
pmc: PMC9187162
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e25768

Informations de copyright

Copyright © 2022, Fontani et al.

Déclaration de conflit d'intérêts

SR and VF are the authors of the REAC patent.. AR and CR are daughters of SR and VF.

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Auteurs

Vania Fontani (V)

Research, Rinaldi Fontani Foundation, Florence, ITA.
Regenerative Medicine, Rinaldi Fontani Institute, Florence, ITA.

Arianna Rinaldi (A)

Biomedical Sciences, University of Sassari, Sassari, ITA.

Chiara Rinaldi (C)

Neuroscience, Psychology, Drug Area and Child Health (NEUROFARBA), University of Florence, Florence, ITA.

Laura Araldi (L)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Alida Azzarà (A)

Obstetrics and Gynecology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Antonio M Carta (AM)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Nicoletta Casale (N)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Alessandro Castagna (A)

Regenerative Medicine, Rinaldi Fontani Institute, Florence, ITA.

Maurizio Del Medico (M)

Medical Physics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Maurizio Di Stasio (M)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Marina Facchini (M)

Neurology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Monica Greco (M)

Geriatrics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Savino LaMarca (S)

Oral Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Giovanni Loro (G)

Diabetes and Endocrinology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Anna Marrone (A)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Alessandra Palattella (A)

Psychiatry, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Giulio Pellegata (G)

Anesthesiology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Daniele Ruini (D)

Family Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Corrado Schmitt (C)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Franco Vianini (F)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Margherita Maioli (M)

Biomedical Sciences, University of Sassari, Sassari, ITA.

Carlo Ventura (C)

Cardiology and Microbiology, National Laboratory of Molecular Biology and Stem Cell Engineering, National Institute of Biostructures and Biosystems, Bologna, ITA.

Franco Caltabiano (F)

Surgery and Urology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, Florence, ITA.

Adriano J Bueno (AJ)

Orthopaedics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Amélia Fugino Matuoka (A)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Edison Massahiro Nabechima (E)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Fabio A Bechelli (FA)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Fabricio da Silveira Bossi (F)

Surgery, Endoscopy and Gastroenterology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Greice C Nitschke Fontana (GC)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Jaques Finkielsztejn (J)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

José Alfredo Coelho Pereira (JA)

Research, Rinaldi Fontani Foundation, Florence, ITA.

Juarez Nunes Callegaro (J)

Psychiatry, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Kleiner Vasconcelos Pinheiro (K)

Integrative/Complementary Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Lara R Ferreira Alves (LR)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Marcelo Kodja Daguer (M)

Orthopaedics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Márcia C Marins Martins (MC)

Pediatrics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Mauricio Bezerra Uliana (M)

Orthopaedics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Nelson Knop Zisman (N)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Paulo Cezar Schütz (P)

Orthopaedics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Paulo R Fochesato (PR)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Pollyanna Celso Felipe de Castro (P)

Neurology, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Rosa M Tanaka Nabechima (RM)

Internal Medicine, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Roseli B Randon (RB)

Pediatrics, International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology, São Paulo, BRA.

Salvatore Rinaldi (S)

Research, Rinaldi Fontani Foundation, Florence, ITA.
Regenerative Medicine, Rinaldi Fontani Institute, Florence, ITA.

Classifications MeSH