Efficacy and safety of capsule endoscopy in octogenarian patients: a retrospective study.


Journal

Minerva gastroenterology
ISSN: 2724-5365
Titre abrégé: Minerva Gastroenterol (Torino)
Pays: Italy
ID NLM: 101777280

Informations de publication

Date de publication:
Sep 2023
Historique:
medline: 31 8 2023
pubmed: 17 6 2022
entrez: 16 6 2022
Statut: ppublish

Résumé

Life expectancy and the number of ultra-octogenarians increased significantly, thus making crucial the appropriateness of several endoscopic procedures in elderly patients. The aim of our study was to provide a retrospective analysis of the efficacy and safety of capsule endoscopy (CE) in patients aged over 80 years. In this single-centre study, 900 patients underwent capsule endoscopy between 2002 and 2015 for different indications; of these 106 patients aged ≥80 years (group A) and 99 patients aged 40-60 years (control group B) were retrospectively selected. Occult gastrointestinal bleeding accounted for 62.1% of all indications for capsule endoscopy in group B, compared to 95.2% in group A (P<0.001). Although not statistically significant, the diagnostic yield was higher in group A (71%) vs. group B (62%). The percentages of reaching the cecum and the median gastric transit time were uniform within the two groups. In contrast, small bowel transit time was longer in group A vs. B. Small bowel preparation was similar in the two groups. The exam was generally well tolerated in both groups, with capsule aspiration being one of the main adverse events, which occurred in two elderly patients. Our data expand previous findings confirming that capsule endoscopy can be performed safely even in very old patients and show that the diagnostic yield is similar to that of younger patients.

Sections du résumé

BACKGROUND BACKGROUND
Life expectancy and the number of ultra-octogenarians increased significantly, thus making crucial the appropriateness of several endoscopic procedures in elderly patients. The aim of our study was to provide a retrospective analysis of the efficacy and safety of capsule endoscopy (CE) in patients aged over 80 years.
METHODS METHODS
In this single-centre study, 900 patients underwent capsule endoscopy between 2002 and 2015 for different indications; of these 106 patients aged ≥80 years (group A) and 99 patients aged 40-60 years (control group B) were retrospectively selected.
RESULTS RESULTS
Occult gastrointestinal bleeding accounted for 62.1% of all indications for capsule endoscopy in group B, compared to 95.2% in group A (P<0.001). Although not statistically significant, the diagnostic yield was higher in group A (71%) vs. group B (62%). The percentages of reaching the cecum and the median gastric transit time were uniform within the two groups. In contrast, small bowel transit time was longer in group A vs. B. Small bowel preparation was similar in the two groups. The exam was generally well tolerated in both groups, with capsule aspiration being one of the main adverse events, which occurred in two elderly patients.
CONCLUSIONS CONCLUSIONS
Our data expand previous findings confirming that capsule endoscopy can be performed safely even in very old patients and show that the diagnostic yield is similar to that of younger patients.

Identifiants

pubmed: 35708039
pii: S2724-5985.22.03220-X
doi: 10.23736/S2724-5985.22.03220-X
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

388-395

Auteurs

Alessandro Pezzoli (A)

Department of Gastroenterology and Gastrointestinal Endoscopy, University Hospital of Ferrara, Ferrara, Italy.

Matteo Guarino (M)

Department of Translational Medicine, University Hospital of Ferrara, Ferrara, Italy.

Nadia Fusetti (N)

Department of Gastroenterology and Gastrointestinal Endoscopy, University Hospital of Ferrara, Ferrara, Italy.

Elena Pizzo (E)

Department of Applied Health Research, University College of London, London, UK.

Marzia Simoni (M)

Epidemiological Unit of CNR Institute of Clinical Physiology, Pisa, Italy.

Loredana Simone (L)

Department of Gastroenterology and Gastrointestinal Endoscopy, University Hospital of Ferrara, Ferrara, Italy.

Viviana Cifalà (V)

Department of Gastroenterology and Gastrointestinal Endoscopy, University Hospital of Ferrara, Ferrara, Italy.

Riccardo Solimando (R)

Department of Gastroenterology and Gastrointestinal Endoscopy, University Hospital of Ferrara, Ferrara, Italy.

Benedetta Perna (B)

Department of Translational Medicine, University Hospital of Ferrara, Ferrara, Italy.

Gianni Testino (G)

Unit of Addiction and Hepatology, Regional Centre on Alcohol, ASL3 San Martino Hospital, Genoa, Italy.

Rinaldo Pellicano (R)

Unit of Gastroenterology, Molinette Hospital, Turin, Italy - roberto.degiorgio@unife.it.

Giacomo Caio (G)

Department of Translational Medicine, University Hospital of Ferrara, Ferrara, Italy.

Lisa Lungaro (L)

Department of Translational Medicine, University Hospital of Ferrara, Ferrara, Italy.

Fabio Caputo (F)

Department of Translational Medicine, University Hospital of Ferrara, Ferrara, Italy.

Giorgio Zoli (G)

Department of Translational Medicine, University Hospital of Ferrara, Ferrara, Italy.

Alberto Merighi (A)

Department of Gastroenterology and Gastrointestinal Endoscopy, University Hospital of Ferrara, Ferrara, Italy.

Roberto DE Giorgio (R)

Department of Translational Medicine, University Hospital of Ferrara, Ferrara, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH