Targeting cognitive control to reduce anxiety in very young children: A proof of concept study.
ERN
anxiety
cognitive control
intervention
preschool
Journal
Depression and anxiety
ISSN: 1520-6394
Titre abrégé: Depress Anxiety
Pays: United States
ID NLM: 9708816
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
revised:
15
04
2022
received:
04
07
2021
accepted:
09
05
2022
pubmed:
17
6
2022
medline:
9
9
2022
entrez:
16
6
2022
Statut:
ppublish
Résumé
Underdeveloped cognitive control (CC)-the capacity to flexibly adjust to changing environments-may predispose some children to early onset anxiety disorders and represents a promising intervention target. The current study established and pilot-tested "Camp Kidpower"-a novel group-based, interactive CC training intervention-and assessed its impacts on behavioral and neurophysiological indices of CC among preschool children with elevated anxiety symptoms. Forty-four anxious children (4-6 years) were enrolled in Camp Kidpower, delivered in four sessions over 10 days. Before and after camp, children's capacity for CC was measured using well-validated, non-trained behavioral tasks and error-related negativity (ERN). Child anxiety symptoms were measured by parent report on the Spence Preschool Anxiety Scale. Thirty-two children completed the study, as defined by completion of pre- and follow-up assessments and at least three camp sessions. From baseline to after camp, performance on behavioral tests of CC improved, ERN amplitude increased, and anxiety symptoms decreased. Results provide initial evidence that play-based cognitive training targeted to behavioral and brain markers of CC reduces anxiety in preschoolers.
Banques de données
ClinicalTrials.gov
['NCT03093376']
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
646-656Subventions
Organisme : NCATS NIH HHS
ID : UL1 TR002240
Pays : United States
Informations de copyright
© 2022 Wiley Periodicals LLC.
Références
Achenbach, T. M., & Rescorla, L. (2001). ASEBA school-age forms & profiles. Aseba Burlington. http://aseba.com/ordering/ASEBA%20Reliability%20and%20Validity-School%20Age.pdf
Beesdo, K., Bittner, A., Pine, D. S., Stein, M. B., Höfler, M., Lieb, R., & Wittchen, H. -U. (2007). Incidence of social anxiety disorder and the consistent risk for secondary depression in the first three decades of life. Archives of General Psychiatry, 64(8), 903-912.
Bishop, G., Spence, S. H., & McDonald, C. (2003). Can parents and teachers provide a reliable and valid report of behavioral inhibition? Child Development, 74(6), 1899-1917.
Bittner, A., Egger, H. L., Erkanli, A., Jane Costello, E., Foley, D. L., & Angold, A. (2007). What do childhood anxiety disorders predict? Journal of Child Psychology and Psychiatry, 48(12), 1174-1183.
Bufferd, S. J., Dougherty, L. R., Carlson, G. A., Rose, S., & Klein, D. N. (2012). Psychiatric disorders in preschoolers: Continuity from ages 3 to 6. American Journal of Psychiatry, 169(11), 1157-1164.
Buzzell, G. A., Morales, S., Bowers, M. E., Troller-Renfree, S. V., Chronis-Tuscano, A., Pine, D. S., Henderson, H. A., & Fox, N. A. (2021). Inhibitory control and set shifting describe different pathways from behavioral inhibition to socially anxious behavior. Developmental Science, 24, e13040. https://doi.org/10.1111/desc.13040
Carrasco, M., Hong, C., Nienhuis, J. L., Harbin, S. M., Fitzgerald, K. D., Gehring, W. J., & Hanna, G. L. (2013). Increased error-related brain activity in youth with obsessive-compulsive disorder and other anxiety disorders. Neuroscience Letters, 541, 214-218. https://doi.org/10.1016/j.neulet.2013.02.017
Checa, P., Castellanos, M. C., Abundis-Gutierrez, A., & Rueda, M. R. (2014). Development of neural mechanisms of conflict and error processing during childhood: Implications for self-regulation. Frontiers in Psychology, 5, 325. https://doi.org/10.3389/fpsyg.2014.00326
Diamond, A. (2011). Biological and social influences on cognitive control processes dependent on prefrontal cortex. Progress in Brain Research, 189, 319-339. https://doi.org/10.1016/B978-0-444-53884-0.00032-4
Diamond, A. (2013). Executive functions. Annual Review of Psychology, 64, 135-168. https://doi.org/10.1146/annurev-psych-113011-143750
Diamond, A., & Lee, K. (2011). Interventions shown to aid executive function development in children 4 to 12 years old. Science, 333(6045), 959-964. https://doi.org/10.1126/science.1204529
Egger, H. L., Erkanli, A., Keeler, G., Potts, E., Walter, B. K., & Angold, A. (2006). Test-retest reliability of the Preschool Age Psychiatric Assessment (PAPA). Journal of the American Academy of Child and Adolescent Psychiatry, 45, 538-549. https://doi.org/10.1019/01.chi.0000205705.71194.b8
Espinet, S. D., Anderson, J. E., & Zelazo, P. D. (2013). Reflection training improves executive function in preschool-age children: Behavioral and neural effects. Developmental Cognitive Neuroscience, 4, 3-15. https://doi.org/10.1016/j.dcn.2012.11.009
Eysenck, M. W., Derakshan, N., Santos, R., & Calvo, M. G. (2007). Anxiety and cognitive performance: Attentional control theory. Emotion, 7(2), 336-353.
Fitzgerald, K. D., Schroder, H. S., & Marsh, R. (2021). Cognitive control in pediatric obsessive compulsive and anxiety disorders: Brain-behavioral targets for early intervention. Biological Psychiatry, 89, 697-706. https://doi.org/10.1016/j.biopsych.2020.11.012
Gehring, W. J., Goss, B., Coles, M. G., Meyer, D. E., & Donchin, E. (1993). A neural system for error detection and compensation. Psychological Science, 4(6), 385-390.
Grammer, J. K., Carrasco, M., Gehring, W. J., & Morrison, F. J. (2014). Age-related changes in error processing in young children: A school-based investigation. Developmental Cognitive Neuroscience, 9, 93-105. https://doi.org/10.1016/j.dcn.2014.02.001
Gratton, G., Coles, M. G., & Donchin, E. (1983). A new method for off-line removal of ocular artifact. Electroencephalography and Clinical Neurophysiology, 55(4), 468-484.
Hadwin, J. A., & Richards, H. J. (2016). Working memory training and CBT reduces anxiety symptoms and attentional biases to threat: A preliminary study. Frontiers in Psychology, 7, 47.
Hajcak, G. (2012). What we've learned from mistakes: Insights from error-related brain activity. Current Directions in Psychological Science, 21(2), 101-106. https://doi.org/10.1177/0963721412436809
Hajcak, G., Franklin, M. E., Foa, E. B., & Simons, R. F. (2008). Increased error-related brain activity in pediatric obsessive-compulsive disorder before and after treatment. American Journal of Psychiatry, 165, 116-123. https://doi.org/10.1176/appi.ajp.2007.07010143
Halperin, J. M., Marks, D. J., Bedard, A. -C. V., Chacko, A., Curchack, J. T., Yoon, C. A., & Healey, D. M. (2013). Training executive, attention, and motor skills: A proof-of-concept study in preschool children with ADHD. Journal of Attention Disorders, 17(8), 711-721.
Han, G., Helm, J., Lucha, C., Zahn-Waxler, C., Hastings, P. D., & Klimes-Dougan, B. (2016). Are executive functioning deficits concurrently and predictively associated with depressive and anxiety symptoms in adolescents? Journal of Clinical Child & Adolescent Psychology, 45, 44-58. https://doi.org/10.1080/15374416.2015.1041592
Henderson, H. A., Pine, D. A., & Fox, N. A. (2015). Behavioral inhibition and developmental risk: A dual-processing perspective. Neuropsychopharmacology, 40(1), 207-224. https://doi.org/10.1038/npp.2014.189
Hirshfeld-Becker, D. R., Masek, B., Henin, A., Blakely, L. R., Pollock-Wurman, R. A., McQuade, J., DePetrillo, L., Briesch, J., Ollendick, T. H., & Rosenbaum, J. F. (2010). Cognitive behavioral therapy for 4-to 7-year-old children with anxiety disorders: A randomized clinical trial. Journal of Consulting and Clinical Psychology, 78(4), 498-510.
Hopkins, J., Lavigne, J. V., Gouze, K. R., LeBailly, S. A., & Bryant, F. B. (2013). Multi-domain models of risk factors for depression and anxiety symptoms in preschoolers: Evidence for common and specific factors. Journal of Abnormal Child Psychology, 41, 705-722. https://doi.org/10.1007/s10802-013-9723-2
Insel, T. R. (2015). The NIMH experimental medicine initiative. World Psychiatry, 14(2), 151-153. https://doi.org/10.1002/wps.20227
Ip, K. I., Jester, J. M., Sameroff, A., & Olson, S. L. (2019). Linking Research Domain Criteria (RDoC) constructs to developmental psychopathology: The role of self-regulation and emotion knowledge in the development of internalizing and externalizing growth trajectories from ages 3 to 10. Development and Psychopathology, 31, 1-18.
Ip, K. I., Liu, Y., Moser, J., Mannella, K., Hruschak, J., Bilek, E., Muzik, M., Rosenblum, K., & Fitzgerald, K. (2019). Moderation of the relationship between the error-related negativity and anxiety by age and gender in young children: A preliminary investigation. Developmental Cognitive Neuroscience, 39, 100702.
Kavanaugh, B. C., Cancilliere, M. K., Fryc, A., Tirrell, E., Oliveria, J., Oberman, L. M., Wexler, B. E., Carpenter, L. L., & Spirito, A. (2020). Measurement of executive funcitoning with the National Institute of Health Toolbox and the association to anxiety/depressive symptomatology in childhood/adolescence. Child Neuropsychology, 26, 754-769. https://doi.org/10.1080/09297049.2019.1708295
Kertz, S. J., Belden, A. C., Tillman, R., & Luby, J. (2016). Cognitive control deficits in shifting and inhibition in preschool age children are associated with increased depression and anxiety over 7.5 years of development. Journal of Abnormal Child Psychology, 44(6), 1185-1196.
Klawohn, J., Hajcak, G., Amir, N., Kathmann, N., & Riesel, A. (2020). Application of attentional bias modification training to modulate hyperactive error-monitoring in OCD. International Journal of Psychophysiology, 156, 79-86.
Kochanska, G., Murray, K., Jacques, T. Y., Koenig, A. L., & Vandegeest, K. A. (1996). Inhibitory control in young children and its role in emerging internalization. Child Development, 67, 490-507.
Kujawa, A., Weinberg, A., Bunford, N., Fitzgerald, K. D., Hanna, G. L., Monk, C. S., Kennedy, A. E., Klumpp, H., Hajcak, G., & Phan, K. L. (2016). Error-related brain activity in youth and young adults before and after treatment for generalized or social anxiety disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 71, 162-168.
Ladouceur, C. D., Tan, P. Z., Sharma, V., Bylsma, L. M., Silk, J. S., Siegle, G. J., Forbes, E. E., McMakin, D. L., Dahl, R. E., & Kendall, P. C. (2018). Error-related brain activity in pediatric anxiety disorders remains elevated following individual therapy: A randomized clinical trial. Journal of Child Psychology and Psychiatry, 59(11), 1152-1161.
Lawler, J. M., Hruschak, J., Aho, K., Liu, Y., Ip, K. I., Lajiness-O'Neill, R., Rosenblum, K. L., Muzik, M., & Fitzgerald, K. D. (2020). The error-related negativity as a neuromarker of risk or resilience in young children. Brain and Behavior, 11, e02008.
Lin, M. -H., Davies, P. L., Stephens, J., & Gavin, W. J. (2020). Test-retest reliability of electroencephalographic measures of performance monitoring in children and adults. Developmental Neuropsychology, 45(6), 341-366.
Lo, S. L. (2018). A meta-analytic review of the event-related potentials (ERN and N2) in childhood and adolescence: Providing a developmental perspective on the conflict monitoring theory. Developmental Review, 48, 82-112.
Lo, S. L., Schroder, H. S., Fisher, M. E., Durbin, C. E., Fitzgerald, K. D., Danovitch, J. H., & Moser, J. S. (2016). Associations between disorder-specific symptoms of anxiety and error-monitoring brain activity in young children. Journal of Abnormal Child Psychology, 1-10. https://doi.org/10.1007/s10802-016-0247-4
Luna, B., Marek, S., Larsen, B., Tervo-Clemmens, B., & Chahal, R. (2015). An integrative model of the maturation of cognitive control. Annual Review of Neuroscience, 38, 151-170.
McClelland, M. M., Cameron, C. E., Duncan, R., Bowles, R. P., Acock, A. C., Miao, A., & Pratt, M. E. (2014). Predictors of early growth in academic achievement: The head-toes-knees-shoulders task. Frontiers in Psychology, 5, 599.
McTeague, L. M., Goodkind, M. S., & Etkin, A. (2016). Transdiagnostic impairment of cognitive control in mental illness. Journal of Psychiatric Research, 83, 37-46. https://doi.org/10.1016/j.jpsychires.2016.08.001
Meyer, A., Gibby, B., Wissemann, K., Klawohn, J., Hajcak, G., & Schmidt, N. B. (2020). A brief, computerized intervention targeting error sensitivity reduces the error-related negativity. Cognitive, Affective, & Behavioral Neuroscience, 20(1), 172-180.
Meyer, A., Hajcak, G., Torpey, D. C., Kujawa, A., Kim, J., Bufferd, S., Carlson, G., & Klein, D. N. (2012). Increased error-related brain activity in six-year-old children with clinical anxiety. Journal of Abnormal Child Psychology, 41, 1257-1266. https://doi.org/10.1007/s10802-013-9762-8
Meyer, A., & Klein, D. N. (2018). Examining the relationships between error-related brain activity (the ERN) and anxiety disorders versus externalizing disorders in young children: Focusing on cognitive control, fear, and shyness. Comprehensive Psychiatry, 87, 112-119. https://doi.org/10.1016/j.comppsych.2018.09.009
Meyer, A., Weinberg, A., Klein, D. N., & Hajcak, G. (2012). The development of the error-related negativity (ERN) and its relationship with anxiety: Evidence from 8 to 13 year-olds. Developmental Cognitive Neuroscience, 2(1), 152-161.
Monga, S., Rosenbloom, B. N., Tanha, A., Owens, M., & Young, A. (2015). Comparison of child-parent and parent-only cognitive-behavioral therapy programs for anxious children aged 5 to 7 years: Short-and long-term outcomes. Journal of the American Academy of Child & Adolescent Psychiatry, 54(2), 138-146.
Moser, J. S. (2017). The nature of the relationship between anxiety and the error-related negativity across development. Current Behavioral Neuroscience Reports, 4, 309-321. https://doi.org/10.1007/s40473-017-0132-7
Moser, J. S., Moran, T. P., Schroder, H. S., Donnellan, M. B., & Yeung, N. (2013). On the relationship between anxiety and error monitoring: A meta-analysis and conceptual framework. Frontiers in Human Neuroscience, 7, 466. https://doi.org/10.3389/fnhum.2013.00466
Muris, P., van der Pennen, E., Sigmond, R., & Mayer, B. (2008). Symptoms of anxiety, depression, and aggression in non-clinical children: Relationships with self-report and performance-based measures of attention and effortful control. Child Psychiatry and Human Development, 39, 455-467. https://doi.org/10.1007/s10578-008-0101-1
Nelson, B. D., Jackson, F., Amir, N., & Hajcak, G. (2017). Attention bias modification reduces neural correlates of response monitoring. Biological Psychology, 129, 103-110.
Niendam, T. A., Laird, A. R., Ray, K. L., Dean, Y. M., Glahn, D. C., & Carter, C. S. (2012). Meta-analytic evidence for a superordinate cognitive control network subserving diverse executive functions. Cognitive, Affective, & Behavioral Neuroscience, 12(2), 241-268.
Pontifex, M. B., Scudder, M. R., Brown, M. L., O'Leary, K. C., Wu, C. -T., Themanson, J. R., & Hillman, C. H. (2010). On the number of trials necessary for stabilization of error-related brain activity across the life span. Psychophysiology, 47(4), 767-773.
Riesel, A., Endrass, T., Auerbach, L. A., & Kathmann, N. (2015). Overactive performance monitoring as an endophenotype for obsessive-compulsive disorder: Evidence from a treatment study. American Journal of Psychiatry, 172(7), 665-673.
Rutter, M., Bailey, A., & Lord, C. (2003). The social communication questionnaire: Manual. Western Psychological Services.
Shackman, A. J., Salomons, T. V., Slagter, H. A., Fox, A. S., Winter, J. J., & Davidson, R. J. (2011). The integration of negative affect, pain and cognitive control in the cingulate cortex. Nature Reviews Neuroscience, 12(3), 154-167.
Spence, S. H., Rapee, R., McDonald, C., & Ingram, M. (2001). The structure of anxiety symptoms among preschoolers. Behaviour Research and Therapy, 39(11), 1293-1316. https://doi.org/10.1016/S0005-7967(00)00098-X
Tamnes, C. K., Walhovd, K. B., Torstveit, M., Sells, V. T., & Fjell, A. M. (2013). Performance monitoring in children and adolescents: A review of developmental changes in the error-related negativity and brain maturation. Developmental Cognitive Neuroscience, 6, 1-13. https://doi.org/10.1016/j.dcn.2013.05.001
Torpey, D. C., Hajcak, G., Kim, J., Kujawa, A., & Klein, D. N. (2012). Electrocortical and behavioral measures of response monitoring in young children during a Go/No-Go task. Developmental Psychobiology, 54(2), 139-150. https://doi.org/10.1002/dev.20590
Troller-Renfree, S. V., Buzzell, G. A., Pine, D. S., Henderson, H. A., & Fox, N. A. (2019). Consequences of not planning ahead: Reduced proactive control moderations longitudinal relations between behavioral inhibition and anxiety. Journal of the American Academy of Child and Adolescent Psychiatry, 58, 768-775. https://doi.org/10.1016/j.jaac.2018.06.040
Valadez, E. A., Troller-Renfree, S. V., Buzzell, G. A., Henderson, H. A., Chronis-Tuscano, A., Pine, D. S., & Fox, N. A. (2021). Behavioral inhibition and dual mechanisms of anxiety risk: Disentangling neural correlates of proactive and reactive control. JCPP Advances, e12022. https://doi.org/10.1002/jcv2.12022
Veloso, A., Vicente, S. G., & Filipe, M. G. (2020). Effectiveness of cognitive training for school-aged children and adolescents with attention deficit/hyperactivity disorder: A systematic review. Frontiers in Psychology, 10, 2983.
Zelazo, P. D., Anderson, J. E., Richler, J., Wallner-Allen, K., Beaumont, J. L., & Weintraub, S. (2013). II. NIH Toolbox Cognition Battery (CB): Measuring executive function and attention. Monographs of the Society for Research in Child Development, 78(4), 16-33.