General anesthesia and the cortical stranglehold on consciousness.

Anesthesia, General Anesthetics, General / pharmacology Animals Consciousness / physiology Electroencephalography Mice Neurons / physiology Unconsciousness / chemically induced
consciousness cortex general anesthesia layer 5 neuronal synchrony

Journal

Neuron
ISSN: 1097-4199
Titre abrégé: Neuron
Pays: United States
ID NLM: 8809320

Informations de publication

Date de publication:
15 06 2022
Historique:
entrez: 16 6 2022
pubmed: 17 6 2022
medline: 22 6 2022
Statut: ppublish

Résumé

In this issue of Neuron, Bharioke et al. (2022) demonstrate that diverse general anesthetic regimens all reversibly and selectively synchronize spontaneous activity of pyramidal neurons in layer 5 of mouse cortex. We discuss the implications of these findings for the mechanism of consciousness and anesthetic-induced unconsciousness.

Identifiants

DOI: 10.1016/j.neuron.2022.05.014 PMID: 35709695
pubmed: 35709695
pii: S0896-6273(22)00455-X
doi: 10.1016/j.neuron.2022.05.014
pii:
doi:

Substances chimiques

Anesthetics, General 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

1891-1893

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Dinesh Pal (D)

Department of Anesthesiology, Center for Consciousness Science, Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.

George A Mashour (GA)

Department of Anesthesiology, Center for Consciousness Science, Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: gmashour@umich.edu.

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Classifications MeSH

questionsmedicales.fr › Anesthésie et analgésie › Anesthésie › Anesthésie générale › General anesthesia and the cortical...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Dépresseurs du système nerveux central › Anesthésiques › Anesthésiques généraux › General anesthesia and the cortical...
questionsmedicales.fr › Eucaryotes › Animaux › General anesthesia and the cortical...
questionsmedicales.fr › Phénomènes psychologiques › Conscience › General anesthesia and the cortical...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Électrodiagnostic › Électroencéphalographie › General anesthesia and the cortical...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › General anesthesia and the cortical...
questionsmedicales.fr › Cellules › Neurones › General anesthesia and the cortical...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations neurologiques › Perte de conscience › General anesthesia and the cortical...