Spatial profiling of early primate gastrulation in utero.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
09 2022
Historique:
received: 16 07 2020
accepted: 08 06 2022
pubmed: 17 6 2022
medline: 9 9 2022
entrez: 16 6 2022
Statut: ppublish

Résumé

Gastrulation controls the emergence of cellular diversity and axis patterning in the early embryo. In mammals, this transformation is orchestrated by dynamic signalling centres at the interface of embryonic and extraembryonic tissues

Identifiants

pubmed: 35709828
doi: 10.1038/s41586-022-04953-1
pii: 10.1038/s41586-022-04953-1
pmc: PMC7614364
mid: EMS172351
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

136-143

Subventions

Organisme : Wellcome Trust
ID : 206684
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 206684/Z/17/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : WT RG89228
Pays : United Kingdom
Organisme : Wellcome Trust
ID : WT108438/C/15/Z
Pays : United Kingdom

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Sophie Bergmann (S)

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
Jeffrey Cheah Biomedical Centre, Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.

Christopher A Penfold (CA)

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
Jeffrey Cheah Biomedical Centre, Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.
Wellcome Trust-Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.

Erin Slatery (E)

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
Jeffrey Cheah Biomedical Centre, Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.

Dylan Siriwardena (D)

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
Jeffrey Cheah Biomedical Centre, Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.

Charis Drummer (C)

Research Platform Degenerative Diseases, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
DZHK (German Center for Cardiovascular Research), partner site Göttingen, Göttingen, Germany.

Stephen Clark (S)

Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
Epigenetics Programme, Babraham Institute, Cambridge, UK.

Stanley E Strawbridge (SE)

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Jeffrey Cheah Biomedical Centre, Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.

Keiko Kishimoto (K)

Department of Marmoset Biology and Medicine, Central Institute for Experimental Animals, Kawasaki, Japan.

Alice Vickers (A)

Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, UK.

Mukul Tewary (M)

Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, UK.

Timo N Kohler (TN)

Department of Biochemistry, University of Cambridge, Cambridge, UK.

Florian Hollfelder (F)

Department of Biochemistry, University of Cambridge, Cambridge, UK.

Wolf Reik (W)

Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
Epigenetics Programme, Babraham Institute, Cambridge, UK.

Erika Sasaki (E)

Department of Marmoset Biology and Medicine, Central Institute for Experimental Animals, Kawasaki, Japan.

Rüdiger Behr (R)

Research Platform Degenerative Diseases, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
DZHK (German Center for Cardiovascular Research), partner site Göttingen, Göttingen, Germany.

Thorsten E Boroviak (TE)

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. teb45@cam.ac.uk.
Centre for Trophoblast Research, University of Cambridge, Cambridge, UK. teb45@cam.ac.uk.
Jeffrey Cheah Biomedical Centre, Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK. teb45@cam.ac.uk.

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