Metal Oxide Laser Ionization Mass Spectrometry Imaging of Fatty Acids and Their Double Bond Positional Isomers.

Animals Carbon / chemistry Fatty Acids / analysis Lasers Mice Oxides Ozone Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods

Journal

Analytical chemistry
ISSN: 1520-6882
Titre abrégé: Anal Chem
Pays: United States
ID NLM: 0370536

Informations de publication

Date de publication:
28 06 2022
Historique:
pubmed: 18 6 2022
medline: 30 6 2022
entrez: 17 6 2022
Statut: ppublish

Résumé

We present a novel combination of a metal oxide laser ionization mass spectrometry imaging (MOLI MSI) technique with off-line lipid derivatization by ozone for the detection of fatty acids (FA) and their carbon-carbon double bond (C═C) positional isomers in biological tissues. MOLI MSI experiments were realized with CeO

Identifiants

DOI: 10.1021/acs.analchem.2c00551 PMID: 35713244
pubmed: 35713244
doi: 10.1021/acs.analchem.2c00551
doi:

Substances chimiques

Fatty Acids 0
Oxides 0
Ozone 66H7ZZK23N
Carbon 7440-44-0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8928-8936

Auteurs

Monika Koktavá (M)

Department of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.

Jan Valášek (J)

Department of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.

Dominika Bezdeková (D)

Department of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.

Vadym Prysiazhnyi (V)

Department of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.
ORCID: 0000-0001-7424-5949

Barbora Adamová (B)

Department of Experimental Biology, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.

Petr Beneš (P)

Department of Experimental Biology, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.
International Clinical Research Center, St. Anne's University Hospital, 656 91 Brno, Czech Republic.

Jarmila Navrátilová (J)

Department of Experimental Biology, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.
International Clinical Research Center, St. Anne's University Hospital, 656 91 Brno, Czech Republic.
ORCID: 0000-0002-3329-3108

Michal Hendrych (M)

First Department of Pathology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, 656 91 Brno, Czech Republic.

Petr Vlček (P)

First Department of Surgery, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, 656 91 Brno, Czech Republic.

Jan Preisler (J)

Department of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.
ORCID: 0000-0002-9819-1284

Antonín Bednařík (A)

Department of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.
ORCID: 0000-0002-8811-0719

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Metal Oxide Laser Ionization Mass Spectrometry...
questionsmedicales.fr › Produits chimiques inorganiques › Éléments › Carbone › Metal Oxide Laser Ionization Mass Spectrometry...
questionsmedicales.fr › Lipides › Acides gras › Metal Oxide Laser Ionization Mass Spectrometry...
questionsmedicales.fr › Équipement et fournitures › Équipement et fournitures pour les applications des radiations › Lasers › Metal Oxide Laser Ionization Mass Spectrometry...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Metal Oxide Laser Ionization Mass Spectrometry...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Metal Oxide Laser Ionization Mass Spectrometry...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Oxygène › Ozone › Metal Oxide Laser Ionization Mass Spectrometry...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse MALDI › Metal Oxide Laser Ionization Mass Spectrometry...