Modifiable prognostic factors of high costs related to healthcare utilization among older people seeking primary care due to back pain: an identification and replication study.


Journal

BMC health services research
ISSN: 1472-6963
Titre abrégé: BMC Health Serv Res
Pays: England
ID NLM: 101088677

Informations de publication

Date de publication:
18 Jun 2022
Historique:
received: 17 12 2021
accepted: 13 06 2022
entrez: 18 6 2022
pubmed: 19 6 2022
medline: 22 6 2022
Statut: epublish

Résumé

Back pain is an extensive burden to our healthcare system, yet few studies have explored modifiable prognostic factors associated with high costs related to healthcare utilization, especially among older back pain patients. The aims of this study were to identify modifiable prognostic factors for high costs related to healthcare utilization among older people seeking primary care with a new episode of back pain; and to replicate the identified associations in a similar cohort, in a different country. Data from two cohort studies within the BACE consortium were used, including 452 and 675 people aged ≥55 years seeking primary care with a new episode of back pain. High costs were defined as costs in the top 25th percentile. Healthcare utilization was self-reported, aggregated for one-year of follow-up and included: primary care consultations, medications, examinations, hospitalization, rehabilitation stay and operations. Costs were estimated based on unit costs collected from national pricelists. Nine potential modifiable prognostic factors were selected based on previous literature. Univariable and multivariable binary logistic regression models were used to identify and replicate associations (crude and adjusted for selected covariates) between each modifiable prognostic factor and high costs related to healthcare utilization. Four modifiable prognostic factors associated with high costs related to healthcare utilization were identified and replicated: a higher degree of pain severity, disability, depression, and a lower degree of physical health-related quality of life. Kinesiophobia and recovery expectations showed no prognostic value. There were inconsistent results across the two cohorts with regards to comorbidity, radiating pain below the knee and mental health-related quality of life. The factors identified in this study may be future targets for intervention with the potential to reduce high costs related to healthcare utilization among older back pain patients. ClinicalTrials.gov NCT04261309, 07 February 2020. Retrospectively registered.

Sections du résumé

BACKGROUND BACKGROUND
Back pain is an extensive burden to our healthcare system, yet few studies have explored modifiable prognostic factors associated with high costs related to healthcare utilization, especially among older back pain patients. The aims of this study were to identify modifiable prognostic factors for high costs related to healthcare utilization among older people seeking primary care with a new episode of back pain; and to replicate the identified associations in a similar cohort, in a different country.
METHODS METHODS
Data from two cohort studies within the BACE consortium were used, including 452 and 675 people aged ≥55 years seeking primary care with a new episode of back pain. High costs were defined as costs in the top 25th percentile. Healthcare utilization was self-reported, aggregated for one-year of follow-up and included: primary care consultations, medications, examinations, hospitalization, rehabilitation stay and operations. Costs were estimated based on unit costs collected from national pricelists. Nine potential modifiable prognostic factors were selected based on previous literature. Univariable and multivariable binary logistic regression models were used to identify and replicate associations (crude and adjusted for selected covariates) between each modifiable prognostic factor and high costs related to healthcare utilization.
RESULTS RESULTS
Four modifiable prognostic factors associated with high costs related to healthcare utilization were identified and replicated: a higher degree of pain severity, disability, depression, and a lower degree of physical health-related quality of life. Kinesiophobia and recovery expectations showed no prognostic value. There were inconsistent results across the two cohorts with regards to comorbidity, radiating pain below the knee and mental health-related quality of life.
CONCLUSION CONCLUSIONS
The factors identified in this study may be future targets for intervention with the potential to reduce high costs related to healthcare utilization among older back pain patients.
TRIAL REGISTRATION BACKGROUND
ClinicalTrials.gov NCT04261309, 07 February 2020. Retrospectively registered.

Identifiants

pubmed: 35717179
doi: 10.1186/s12913-022-08180-2
pii: 10.1186/s12913-022-08180-2
pmc: PMC9206382
doi:

Banques de données

ClinicalTrials.gov
['NCT04261309']

Types de publication

Clinical Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

793

Informations de copyright

© 2022. The Author(s).

Références

BMC Health Serv Res. 2018 Aug 20;18(1):648
pubmed: 30126409
PLoS Med. 2013;10(2):e1001380
pubmed: 23393429
PLoS One. 2019 Nov 11;14(11):e0225125
pubmed: 31710655
BMC Musculoskelet Disord. 2011 Aug 19;12:193
pubmed: 21854620
BMC Musculoskelet Disord. 2015 Apr 02;16:75
pubmed: 25887763
Spine (Phila Pa 1976). 2006 Jan 15;31(2):212-8
pubmed: 16418643
Eur J Pain. 2009 Mar;13(3):280-6
pubmed: 18524652
BMJ. 2013 Feb 05;346:e5595
pubmed: 23386360
Spine (Phila Pa 1976). 2000 Dec 15;25(24):3140-51
pubmed: 11124730
Best Pract Res Clin Rheumatol. 2002 Dec;16(5):761-75
pubmed: 12473272
Osteopath Med Prim Care. 2008 Nov 24;2:11
pubmed: 19025636
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013 May;56(5-6):832-44
pubmed: 23703505
Lancet. 2016 Oct 8;388(10053):1545-1602
pubmed: 27733282
Pain. 1996 May-Jun;65(2-3):197-204
pubmed: 8826507
Lancet. 2012 Dec 15;380(9859):2163-96
pubmed: 23245607
Spine (Phila Pa 1976). 2006 Nov 1;31(23):2724-7
pubmed: 17077742
Spine (Phila Pa 1976). 2019 Apr 1;44(7):E423-E429
pubmed: 30234815
Stat Med. 2016 Mar 30;35(7):1159-77
pubmed: 26514699
Arthritis Care Res (Hoboken). 2014 Aug;66(8):1220-6
pubmed: 24339263
BMJ Open. 2018 Sep 8;8(9):e023113
pubmed: 30196269
Pain. 2020 Sep;161 Suppl 1:S57-S64
pubmed: 33090740
Eur J Pain. 2020 Feb;24(2):325-337
pubmed: 31566839
Spine (Phila Pa 1976). 1983 Mar;8(2):141-4
pubmed: 6222486
BMC Health Serv Res. 2013 Jan 03;13:1
pubmed: 23286781
BMC Med Res Methodol. 2020 Jun 29;20(1):172
pubmed: 32600262
Stat Med. 1996 Feb 28;15(4):361-87
pubmed: 8668867
Spine (Phila Pa 1976). 2010 Aug 15;35(18):1714-20
pubmed: 21374895
J Eval Clin Pract. 2016 Apr;22(2):247-52
pubmed: 26417660
Med Care. 2008 Jul;46(7):647-53
pubmed: 18580382
Health Econ. 2003 May;12(5):377-92
pubmed: 12720255
Nat Rev Dis Primers. 2018 Dec 13;4(1):52
pubmed: 30546064
Br J Cancer. 2005 Aug 22;93(4):387-91
pubmed: 16106245
Eur J Pain. 2010 Aug;14(7):747.e1-7
pubmed: 20036168
PLoS Med. 2014 Oct 14;11(10):e1001744
pubmed: 25314315
Diagn Progn Res. 2019 Aug 22;3:16
pubmed: 31463368
Lancet. 2018 Jun 9;391(10137):2356-2367
pubmed: 29573870
Pharmacoeconomics. 2019 May;37(5):631-643
pubmed: 30746613
Stat Med. 2002 Dec 30;21(24):3803-22
pubmed: 12483768
BMJ. 2015 Aug 11;351:h3868
pubmed: 26264962
PLoS One. 2016 May 27;11(5):e0155982
pubmed: 27232878
Med Care. 1992 Jun;30(6):473-83
pubmed: 1593914
Med Decis Making. 2001 Jan-Feb;21(1):45-56
pubmed: 11206946
Rheumatol Int. 2019 Oct;39(10):1663-1679
pubmed: 31463608
Stat Med. 2000 Apr 30;19(8):1059-79
pubmed: 10790680
Stat Med. 1984 Apr-Jun;3(2):143-52
pubmed: 6463451
BMJ Open. 2021 Sep 17;11(9):e053229
pubmed: 34535487
J Clin Epidemiol. 2017 Feb;82:167-172
pubmed: 27825891
Arthritis Care Res (Hoboken). 2012 Jul;64(7):1084-8
pubmed: 22337573
Lancet. 2018 Jun 9;391(10137):2368-2383
pubmed: 29573872
Eur J Pain. 2007 Apr;11(3):290-8
pubmed: 16677837
Healthc Policy. 2014 Feb;9(3):68-79
pubmed: 24726075
Pain. 2008 Mar;135(1-2):142-50
pubmed: 17611036
Int J Technol Assess Health Care. 2002 Summer;18(3):705-10
pubmed: 12391960
BMC Musculoskelet Disord. 2006 Sep 18;7:72
pubmed: 16982001
J Pain Res. 2015 Aug 12;8:523-35
pubmed: 26316803
BMC Health Serv Res. 2020 Mar 23;20(1):239
pubmed: 32293420
Pain. 1993 Feb;52(2):157-168
pubmed: 8455963
Lancet. 2018 Jun 9;391(10137):2384-2388
pubmed: 29573871
Arthritis Rheum. 2003 Apr 15;49(2):156-63
pubmed: 12687505
Bull World Health Organ. 2019 Jun 1;97(6):423-433
pubmed: 31210680
PLoS One. 2017 Nov 9;12(11):e0187477
pubmed: 29121647
Health Econ. 2018 Jun;27(6):1024-1040
pubmed: 29573044
J Occup Environ Med. 2009 Jul;51(7):786-96
pubmed: 19528832

Auteurs

Rikke Munk Killingmo (RM)

Department of Physiotherapy, Oslo Metropolitan University, Oslo, Norway. rikke@oslomet.no.

Alessandro Chiarotto (A)

Department of General Practice, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.

Danielle A van der Windt (DA)

School of Medicine, Keele University, Keele, UK.

Kjersti Storheim (K)

Department of Physiotherapy, Oslo Metropolitan University, Oslo, Norway.
Research and Communication Unit for Musculoskeletal Health (FORMI), Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.

Sita M A Bierma-Zeinstra (SMA)

Department of General Practice, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.
Department of Orthopedics, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.

Milada C Småstuen (MC)

Department of Physiotherapy, Oslo Metropolitan University, Oslo, Norway.

Zinajda Zolic-Karlsson (Z)

HTA and Reimbursement at Norwegian Medicines Agency, Oslo, Norway.

Ørjan N Vigdal (ØN)

Department of Physiotherapy, Oslo Metropolitan University, Oslo, Norway.

Bart W Koes (BW)

Department of General Practice, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.
Center for Muscle and Joint Health, University of Southern Denmark, Odense, Denmark.

Margreth Grotle (M)

Department of Physiotherapy, Oslo Metropolitan University, Oslo, Norway.
Department of General Practice, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.

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