[Prescriptions of statins in the elderly according to the type of healthcare establishment: An example of the usefulness of territorial hospital groups].

Utilisations des statines chez le sujet âgé selon le type de prise en charge : un exemple de l’intérêt des groupements hospitaliers de territoire.
Aged Analyse pharmaceutique Continuity of patient care Groupements hospitaliers de territoires Health area Hydroxymethylglutaryl-CoA reductase inhibitors Inhibiteurs de l’HMG-CoA réductase Interventions pharmaceutiques Parcours patient Patients âgés Pharmacien Pharmacien hospitalier Pharmacists Physicians Practice patterns Prescriptions Primary prevention Propositions d’optimisation thérapeutique Prévention primaire Statins Territorial hospital group Therapeutic optimizations

Journal

Annales pharmaceutiques francaises
ISSN: 0003-4509
Titre abrégé: Ann Pharm Fr
Pays: France
ID NLM: 2985176R

Informations de publication

Date de publication:
Mar 2023
Historique:
received: 11 10 2021
revised: 13 06 2022
accepted: 14 06 2022
pubmed: 22 6 2022
medline: 7 3 2023
entrez: 21 6 2022
Statut: ppublish

Résumé

The challenge of territorial hospital groups is to develop coherent care pathways for optimal patient care. Following the creation of a territorial pharmaceutical team, a common prescription review process was initiated in our health area. The objective of this study is to analyze the uses of statins in the elderly. The study included all statin-treated patients older than 75 years at the five participating institutions (including long-term nursing homes). In a prospective multicenter study, the benefit/risk ratio of statin prescription has been assessed up. Depending on the clinical situation, a proposal to stop or adjust the dosage could be made. Nine hundred and forty-seven patients were included. Among them, 184 were treated with a statin. Forty-seven patients (26%) are treated in primary prevention and 137 patients (74%) in secondary prevention. Dosages are lower for long stays. Fifteen treatments interruption were accepted out of 44 proposals, mostly for long stays. The reasons given to continue treatment are the need for a new evaluation by a cardiologist or a high cardiovascular risk. The variability of results according to the type healthcare institution makes territorial medical and pharmaceutical collaboration relevant. The challenge is to develop a coherent care pathway for optimal care of elderly patients, with congruent objectives.

Identifiants

pubmed: 35728628
pii: S0003-4509(22)00080-3
doi: 10.1016/j.pharma.2022.06.004
pii:
doi:

Substances chimiques

Hydroxymethylglutaryl-CoA Reductase Inhibitors 0
Pharmaceutical Preparations 0

Types de publication

Multicenter Study English Abstract Journal Article

Langues

fre

Sous-ensembles de citation

IM

Pagination

346-353

Informations de copyright

Copyright © 2022 Académie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.

Auteurs

A Amsallem (A)

Pôle pharmaceutique, CHRU Jean-Minjoz, 3, boulevard Alexander-Fleming, 25030 Besançon cedex, France.

J Berthou-Contreras (J)

Pôle pharmaceutique, CHRU Jean-Minjoz, 3, boulevard Alexander-Fleming, 25030 Besançon cedex, France.

N Joret (N)

Pôle pharmaceutique, CHRU Jean-Minjoz, 3, boulevard Alexander-Fleming, 25030 Besançon cedex, France.

S Koeberlé (S)

Service de court séjour gériatrique, CHRU Jean-Minjoz, Besançon, France; Équipe « Éthique et progrès médical », Inserm, CIC 1431, université Bourgogne Franche-Comté, Besançon, France.

S Limat (S)

Pôle pharmaceutique, CHRU Jean-Minjoz, 3, boulevard Alexander-Fleming, 25030 Besançon cedex, France; Inserm, EFS BFC, UMR 1098, université de Bourgogne Franche-Comté, Besançon, France.

A-L Clairet (AL)

Pôle pharmaceutique, CHRU Jean-Minjoz, 3, boulevard Alexander-Fleming, 25030 Besançon cedex, France; Inserm, EFS BFC, UMR 1098, université de Bourgogne Franche-Comté, Besançon, France. Electronic address: alclairet@chu-besancon.fr.

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Classifications MeSH