Ellipsoid calculations versus manual tumor delineations for glioblastoma tumor volume evaluation.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
22 06 2022
Historique:
received: 17 06 2020
accepted: 27 05 2022
entrez: 22 6 2022
pubmed: 23 6 2022
medline: 25 6 2022
Statut: epublish

Résumé

In glioblastoma, the response to treatment assessment is essentially based on the 2D tumor size evolution but remains disputable. Volumetric approaches were evaluated for a more accurate estimation of tumor size. This study included 57 patients and compared two volume measurement methods to determine the size of different glioblastoma regions of interest: the contrast-enhancing area, the necrotic area, the gross target volume and the volume of the edema area. The two methods, the ellipsoid formula (the calculated method) and the manual delineation (the measured method) showed a high correlation to determine glioblastoma volume and a high agreement to classify patients assessment response to treatment according to RANO criteria. This study revealed that calculated and measured methods could be used in clinical practice to estimate glioblastoma volume size and to evaluate tumor size evolution.

Identifiants

pubmed: 35732848
doi: 10.1038/s41598-022-13739-4
pii: 10.1038/s41598-022-13739-4
pmc: PMC9217851
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

10502

Informations de copyright

© 2022. The Author(s).

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Auteurs

Clara Le Fèvre (C)

Department of Radiotherapy, ICANS, Institut Cancérologie Strasbourg Europe, 17 Rue Albert Calmette, 67200, Strasbourg Cedex, France. c.lefevre@icans.eu.

Roger Sun (R)

Department of Radiotherapy, Institut Gustave Roussy, Paris-Saclay University, Villejuif, France.

Hélène Cebula (H)

Department of Neurosurgery, Hôpital d'Hautepierre, 1, Avenue Molière, 67200, Strasbourg, France.

Alicia Thiery (A)

Department of Public Health, ICANS, Institut Cancérologie Strasbourg Europe, 17 Rue Albert Calmette, 67200, Strasbourg Cedex, France. a.thiery@icans.eu.

Delphine Antoni (D)

Department of Radiotherapy, ICANS, Institut Cancérologie Strasbourg Europe, 17 Rue Albert Calmette, 67200, Strasbourg Cedex, France.

Roland Schott (R)

Department of Medical Oncology, ICANS, Institut Cancérologie Strasbourg Europe, 17 Rue Albert Calmette, 67200, Strasbourg Cedex, France.

François Proust (F)

Department of Neurosurgery, Hôpital d'Hautepierre, 1, Avenue Molière, 67200, Strasbourg, France.

Jean-Marc Constans (JM)

Department of Radiology, Centre Hospitalier Universitaire d' Amiens, 1 Rond-Point du Professeur Christian Cabrol, 80054, Amiens Cedex 1, France.

Georges Noël (G)

Department of Radiotherapy, ICANS, Institut Cancérologie Strasbourg Europe, 17 Rue Albert Calmette, 67200, Strasbourg Cedex, France.

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