SARS-CoV-2 infection of human brain microvascular endothelial cells leads to inflammatory activation through NF-κB non-canonical pathway and mitochondrial remodeling.
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
16 Jun 2022
16 Jun 2022
Historique:
entrez:
23
6
2022
pubmed:
24
6
2022
medline:
24
6
2022
Statut:
epublish
Résumé
Neurological effects of COVID-19 and long-COVID-19 as well as neuroinvasion by SARS-CoV-2 still pose several questions and are of both clinical and scientific relevance. We described the cellular and molecular effects of the human brain microvascular endothelial cells (HBMECs)
Identifiants
pubmed: 35734080
doi: 10.1101/2022.06.16.496324
pmc: PMC9216721
pii:
doi:
Types de publication
Preprint
Langues
eng
Subventions
Organisme : NIMH NIH HHS
ID : R01 MH128022
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA044579
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL126559
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA039576
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA050528
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA040537
Pays : United States
Organisme : NIMH NIH HHS
ID : R21 MH122235
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA047157
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH072567
Pays : United States
Commentaires et corrections
Type : UpdateIn
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