Microbiological Characterisation of Community-Acquired Urinary Tract Infections in Bagamoyo, Tanzania: A Prospective Study.

Escherichia coli Klebsiella spp. antimicrobial susceptibility bacteria diagnosis infection

Journal

Tropical medicine and infectious disease
ISSN: 2414-6366
Titre abrégé: Trop Med Infect Dis
Pays: Switzerland
ID NLM: 101709042

Informations de publication

Date de publication:
12 Jun 2022
Historique:
received: 05 05 2022
revised: 06 06 2022
accepted: 08 06 2022
entrez: 23 6 2022
pubmed: 24 6 2022
medline: 24 6 2022
Statut: epublish

Résumé

Urinary tract infections (UTIs) are among the most common infections in sub-Saharan Africa, but microbiological data to guide treatment decisions are limited. Hence, we investigated the bacterial aetiology and corresponding antimicrobial susceptibility patterns in outpatients with UTIs in Bagamoyo, Tanzania. Urine samples from symptomatic individuals were subjected to microbiological examinations for bacterial species identification using conventional methods and disc diffusion-based resistance testing. Subsequently, urine samples were transferred to Germany for confirmatory diagnostics using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry and automated resistance testing. Overall, 104 out of 270 (38.5%) individuals had a positive urine culture and 119 putative pathogens were identified. The most frequently detected bacteria were

Identifiants

pubmed: 35736979
pii: tropicalmed7060100
doi: 10.3390/tropicalmed7060100
pmc: PMC9228238
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Joseph Schmider (J)

Institute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg, Germany.

Nina Bühler (N)

Institute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg, Germany.

Hasina Mkwatta (H)

Ifakara Health Institute, Bagamoyo Branch, Bagamoyo P.O. Box 74, Tanzania.

Anna Lechleiter (A)

Institute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg, Germany.

Tarsis Mlaganile (T)

Ifakara Health Institute, Bagamoyo Branch, Bagamoyo P.O. Box 74, Tanzania.

Jürg Utzinger (J)

Swiss Tropical and Public Health Institute, CH-4123 Allschwil, Switzerland.
University of Basel, CH-4003 Basel, Switzerland.

Tutu Mzee (T)

Ifakara Health Institute, Bagamoyo Branch, Bagamoyo P.O. Box 74, Tanzania.

Theckla Kazimoto (T)

Institute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg, Germany.
Ifakara Health Institute, Bagamoyo Branch, Bagamoyo P.O. Box 74, Tanzania.

Sören L Becker (SL)

Institute of Medical Microbiology and Hygiene, Saarland University, 66421 Homburg, Germany.
Swiss Tropical and Public Health Institute, CH-4123 Allschwil, Switzerland.
University of Basel, CH-4003 Basel, Switzerland.

Classifications MeSH