Alzheimer's disease pattern derived from relative cerebral flow as an alternative for the metabolic pattern using SSM/PCA.

Alzheimer’s disease Disease pattern Relative cerebral blood flow SSM/PCA

Journal

EJNMMI research
ISSN: 2191-219X
Titre abrégé: EJNMMI Res
Pays: Germany
ID NLM: 101560946

Informations de publication

Date de publication:
23 Jun 2022
Historique:
received: 12 01 2022
accepted: 15 06 2022
entrez: 23 6 2022
pubmed: 24 6 2022
medline: 24 6 2022
Statut: epublish

Résumé

2-Deoxy-2-[ In general, the rCBF and FDG AD-DPs were characterized by a reduction in cortical frontal, temporal, and parietal lobes. FDG and rCBF methods presented similar score distribution. rCBF images may provide an alternative for FDG PET scans for the identification of AD patients through SSM/PCA.

Sections du résumé

BACKGROUND BACKGROUND
2-Deoxy-2-[
RESULTS RESULTS
In general, the rCBF and FDG AD-DPs were characterized by a reduction in cortical frontal, temporal, and parietal lobes. FDG and rCBF methods presented similar score distribution.
CONCLUSION CONCLUSIONS
rCBF images may provide an alternative for FDG PET scans for the identification of AD patients through SSM/PCA.

Identifiants

pubmed: 35737201
doi: 10.1186/s13550-022-00909-8
pii: 10.1186/s13550-022-00909-8
pmc: PMC9226207
doi:

Types de publication

Journal Article

Langues

eng

Pagination

37

Informations de copyright

© 2022. The Author(s).

Références

EJNMMI Res. 2019 Jul 4;9(1):59
pubmed: 31273465
Cancer. 1950 Jan;3(1):32-5
pubmed: 15405679
J Nucl Med. 2011 Aug;52(8):1218-26
pubmed: 21764801
Neuroimage. 2002 Sep;17(1):302-16
pubmed: 12482085
J Nucl Med. 2016 Jul;57(7):1071-7
pubmed: 26912447
Mov Disord. 2010 Oct 30;25(14):2395-404
pubmed: 20669302
J Cereb Blood Flow Metab. 2017 Feb;37(2):740-749
pubmed: 27107028
Cereb Cortex. 2009 Feb;19(2):375-82
pubmed: 18534991
Magn Reson Med. 2000 Sep;44(3):450-6
pubmed: 10975898
Arch Neurol. 2001 Dec;58(12):1985-92
pubmed: 11735772
Neuroscientist. 2017 Dec;23(6):616-626
pubmed: 28406055
Contrast Media Mol Imaging. 2018 Jan 8;2018:6830105
pubmed: 29531506
J Alzheimers Dis. 2015;44(3):815-26
pubmed: 25362041
Alzheimers Dement. 2018 Apr;14(4):535-562
pubmed: 29653606
Hum Brain Mapp. 2003 Aug;19(4):224-47
pubmed: 12874777
J Alzheimers Dis. 2018;65(1):89-97
pubmed: 30056421
J Nucl Med. 2011 Feb;52(2):173-9
pubmed: 21233181
Neuroimage. 1995 Jun;2(2):148-56
pubmed: 9343597
Neuroimage Clin. 2021;30:102625
pubmed: 33756179
J Neurol Sci. 2000 Dec 1;181(1-2):19-28
pubmed: 11099707
Alzheimers Dement (Amst). 2019 Jun 22;11:472-482
pubmed: 31294076
Eur J Nucl Med Mol Imaging. 2020 Dec;47(13):3165-3175
pubmed: 32462397
J Nucl Med. 2007 Apr;48(4):547-52
pubmed: 17401090
Neurology. 2011 Nov 29;77(22):1977-85
pubmed: 22094481
J Nucl Med. 2011 Mar;52(3):393-400
pubmed: 21321269
Eur J Nucl Med Mol Imaging. 2021 Jul;48(8):2320-2324
pubmed: 33876260
PLoS One. 2019 Jan 17;14(1):e0211000
pubmed: 30653612
Neuroimage. 2010 Apr 15;50(3):935-49
pubmed: 20079441
Neuroimage. 2009 May 1;45(4):1241-52
pubmed: 19349238
Biochem Med (Zagreb). 2015 Jun 05;25(2):141-51
pubmed: 26110027
Trends Neurosci. 2009 Oct;32(10):548-57
pubmed: 19765835
Neuroimage. 1996 Dec;4(3 Pt 1):153-8
pubmed: 9345505
J Nucl Med. 2017 Jul;58(7):1132-1139
pubmed: 28280223
J Nucl Med. 2015 Aug;56(8):1199-205
pubmed: 26045309
Nucl Med Commun. 2006 Sep;27(9):739-43
pubmed: 16894329
Eur J Nucl Med Mol Imaging. 2016 Feb;43(2):374-385
pubmed: 26613792
Ann Neurol. 2004 Mar;55(3):306-19
pubmed: 14991808

Auteurs

Débora E Peretti (DE)

Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

David Vállez García (D)

Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Remco J Renken (RJ)

Department of Biomedical Sciences of Cells and Systems, Cognitive Neuroscience Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Fransje E Reesink (FE)

Department of Neurology, Alzheimer Centre, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Janine Doorduin (J)

Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Bauke M de Jong (BM)

Department of Neurology, Alzheimer Centre, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Peter P De Deyn (PP)

Department of Neurology, Alzheimer Centre, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.

Rudi A J O Dierckx (RAJO)

Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Ronald Boellaard (R)

Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. r.boellaard@amsterdamumc.nl.
Department of Radiology and Nuclear Medicine, Location VU Medical Center, Amsterdam University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. r.boellaard@amsterdamumc.nl.

Classifications MeSH