The DendrisCHIP
biochips
bone and joint infection
in vitro multiplex diagnostic
microbial cultures
next-generation sequencing
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
30 May 2022
30 May 2022
Historique:
received:
21
04
2022
revised:
20
05
2022
accepted:
24
05
2022
entrez:
24
6
2022
pubmed:
25
6
2022
medline:
25
6
2022
Statut:
epublish
Résumé
Osteoarticular infections are major disabling diseases that can occur after orthopedic implant surgery in patients. The management of these infections is very complex and painful, requiring surgical intervention in combination with long-term antibiotic treatment. Therefore, early and accurate diagnosis of the causal pathogens is essential before formulating chemotherapeutic regimens. Although culture-based microbiology remains the most common diagnosis of osteoarticular infections, its regular failure to identify the causative pathogen as well as its long-term modus operandi motivates the development of rapid, accurate, and sufficiently comprehensive bacterial species-specific diagnostics that must be easy to use by routine clinical laboratories. Based on these criteria, we reported on the feasibility of our DendrisCHIP
Identifiants
pubmed: 35741163
pii: diagnostics12061353
doi: 10.3390/diagnostics12061353
pmc: PMC9222036
pii:
doi:
Types de publication
Journal Article
Langues
eng
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