Role of Nano-miRNAs in Diagnostics and Therapeutics.
nanotechnology biomarker
nano–microRNA
target therapy
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
20 Jun 2022
20 Jun 2022
Historique:
received:
11
05
2022
revised:
15
06
2022
accepted:
17
06
2022
entrez:
24
6
2022
pubmed:
25
6
2022
medline:
28
6
2022
Statut:
epublish
Résumé
MicroRNAs (miRNA) are key regulators of gene expression, controlling different biological processes such as cellular development, differentiation, proliferation, metabolism, and apoptosis. The relationships between miRNA expression and the onset and progression of different diseases, such as tumours, cardiovascular and rheumatic diseases, and neurological disorders, are well known. A nanotechnology-based approach could match miRNA delivery and detection to move beyond the proof-of-concept stage. Different kinds of nanotechnologies can have a major impact on the diagnosis and treatment of miRNA-related diseases such as cancer. Developing novel methodologies aimed at clinical practice represents a big challenge for the early diagnosis of specific diseases. Within this context, nanotechnology represents a wide emerging area at the forefront of research over the last two decades, whose potential has yet to be fully attained. Nanomedicine, derived from nanotechnology, can exploit the unique properties of nanometer-sized particles for diagnostic and therapeutic purposes. Through nanomedicine, specific treatment to counteract only cancer-cell proliferation will be improved, while leaving healthy cells intact. In this review, we dissect the properties of different nanocarriers and their roles in the early detection and treatment of cancer.
Identifiants
pubmed: 35743278
pii: ijms23126836
doi: 10.3390/ijms23126836
pmc: PMC9223810
pii:
doi:
Substances chimiques
MicroRNAs
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Mol Pharm. 2018 Sep 4;15(9):4031-4037
pubmed: 30059228
World J Oncol. 2019 Apr;10(2):63-89
pubmed: 31068988
Biosens Bioelectron. 2018 Mar 15;101:275-281
pubmed: 29096366
Chem Rev. 2012 May 9;112(5):2739-79
pubmed: 22295941
Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19362-19367
pubmed: 31501320
ACS Appl Mater Interfaces. 2019 Nov 27;11(47):43865-43878
pubmed: 31684723
Angew Chem Int Ed Engl. 2020 Aug 10;59(33):14044-14048
pubmed: 32401400
Mol Ther. 2019 Jul 3;27(7):1252-1261
pubmed: 31085078
Nanotechnology. 2017 Jul 14;28(28):285101
pubmed: 28627503
Anal Chim Acta. 2019 Oct 31;1078:176-181
pubmed: 31358217
Anal Chem. 2018 Sep 4;90(17):10144-10151
pubmed: 29974736
Analyst. 2021 Jun 14;146(12):4000-4009
pubmed: 34013303
Biomater Sci. 2019 Oct 1;7(10):4325-4344
pubmed: 31411213
Small. 2019 Dec;15(50):e1904689
pubmed: 31724319
J Control Release. 2021 Feb 10;330:173-184
pubmed: 33316298
ACS Nano. 2021 Apr 27;15(4):6645-6657
pubmed: 33787219
Int J Environ Res Public Health. 2022 Jan 19;19(3):
pubmed: 35162125
Theranostics. 2017 Jan 15;7(3):677-693
pubmed: 28255359
Nanomaterials (Basel). 2021 Jun 20;11(6):
pubmed: 34203018
Biosens Bioelectron. 2020 Feb 15;150:111964
pubmed: 31929092
J Am Chem Soc. 2020 Mar 18;142(11):4996-5001
pubmed: 32134270
Int J Nanomedicine. 2018 Oct 01;13:5865-5886
pubmed: 30319254
Nanotechnology. 2021 Feb 19;32(8):085504
pubmed: 33152726
Annu Rev Anal Chem (Palo Alto Calif). 2015;8:217-37
pubmed: 25973944
Semin Cancer Biol. 2021 Feb;69:100-108
pubmed: 31562954
ACS Nano. 2016 Feb 23;10(2):2028-45
pubmed: 26815014
J Pers Med. 2019 Feb 07;9(1):
pubmed: 30736475
Anal Chim Acta. 2020 Nov 1;1136:1-8
pubmed: 33081933
Anal Chim Acta. 2017 Nov 15;993:55-62
pubmed: 29078955
ACS Nano. 2018 Nov 27;12(11):10817-10832
pubmed: 30346694
Asian J Pharm Sci. 2020 Jan;15(1):69-82
pubmed: 32175019
Chem Soc Rev. 2014 May 21;43(10):3426-52
pubmed: 24549396
Anal Bioanal Chem. 2016 Oct;408(26):7255-64
pubmed: 27497966
Anal Chem. 2017 Nov 7;89(21):11697-11702
pubmed: 29019243
ACS Nano. 2019 Jun 25;13(6):6224-6255
pubmed: 31145587
Anal Chem. 2021 Apr 20;93(15):6270-6277
pubmed: 33821630
Mikrochim Acta. 2019 Aug 30;186(9):661
pubmed: 31471777
Anal Chim Acta. 2011 Aug 12;699(2):134-52
pubmed: 21704768
Life Sci. 2021 Oct 1;282:119800
pubmed: 34245773
Biomaterials. 2021 Sep;276:121036
pubmed: 34329919
Colloids Surf B Biointerfaces. 2022 Feb;210:112260
pubmed: 34894598
Int J Pharm. 2021 Dec 15;610:121256
pubmed: 34732362
Nanotheranostics. 2018 Jan 1;2(1):96-105
pubmed: 29291166
Nanomedicine. 2005 Jun;1(2):101-9
pubmed: 17292064
Biotechnol Adv. 2017 May - Jun;35(3):350-360
pubmed: 28286148
Proteomes. 2022 May 09;10(2):
pubmed: 35645374
Nat Biomed Eng. 2020 Jan;4(1):69-83
pubmed: 31844155
Nanomedicine (Lond). 2018 Nov;13(21):2729-2758
pubmed: 30394201
J Biomed Nanotechnol. 2019 Nov 1;15(11):2240-2250
pubmed: 31847938
Adv Mater. 2021 Jun;33(24):e2100556
pubmed: 33949734
Biomaterials. 2017 Mar;121:144-154
pubmed: 28088076
ACS Appl Mater Interfaces. 2018 Aug 29;10(34):28290-28300
pubmed: 30113161
ACS Sens. 2021 Mar 26;6(3):833-841
pubmed: 33284011
Int J Nanomedicine. 2018 Nov 20;13:7727-7747
pubmed: 30538455
Nanomedicine. 2019 Jul;19:95-105
pubmed: 31028887
Expert Opin Drug Deliv. 2020 Nov;17(11):1541-1554
pubmed: 32791861
Blood. 2019 Aug 1;134(5):432-444
pubmed: 31151986
J Nanobiotechnology. 2018 Apr 13;16(1):40
pubmed: 29653577
Mikrochim Acta. 2019 Feb 1;186(3):132
pubmed: 30707293
Anal Chim Acta. 2020 May 22;1112:24-33
pubmed: 32334679
Int J Mol Sci. 2021 Sep 10;22(18):
pubmed: 34575947
Langmuir. 2006 Jan 3;22(1):32-41
pubmed: 16378396
IET Nanobiotechnol. 2018 Jun;12(4):453-458
pubmed: 29768229
Talanta. 2021 Mar 1;224:121895
pubmed: 33379103
Chemistry. 2014 Jul 28;20(31):9476-92
pubmed: 24989446
Anal Biochem. 2019 Jan 1;564-565:21-31
pubmed: 30292477
J Biomed Nanotechnol. 2020 Nov 1;16(11):1600-1611
pubmed: 33461652
Talanta. 2018 Nov 1;189:592-598
pubmed: 30086965
Talanta. 2017 Nov 1;174:521-526
pubmed: 28738618
Mol Pharm. 2018 Mar 5;15(3):985-993
pubmed: 29432024
ACS Appl Bio Mater. 2021 Dec 20;4(12):8368-8376
pubmed: 35005926
Biomaterials. 2019 Oct;218:119342
pubmed: 31326657
Biosens Bioelectron. 2016 Mar 15;77:99-106
pubmed: 26397420
Mikrochim Acta. 2020 Aug 2;187(8):479
pubmed: 32740774
J Drug Target. 2020 Aug-Sep;28(7-8):818-830
pubmed: 32452217
Chem Rev. 2015 Jan 14;115(1):327-94
pubmed: 25423180
Biomark Med. 2017 Jan;11(1):69-86
pubmed: 27917642
Micromachines (Basel). 2020 Jan 03;11(1):
pubmed: 31947894
Anal Chem. 2018 Nov 6;90(21):12584-12591
pubmed: 30346693
Angew Chem Int Ed Engl. 2008;47(4):644-52
pubmed: 17994653
J Nanobiotechnology. 2020 Apr 28;18(1):65
pubmed: 32345308
Nanotechnology. 2018 Feb 23;29(8):085501
pubmed: 29269591
Carbohydr Polym. 2018 Dec 1;201:131-140
pubmed: 30241804
Biosens Bioelectron. 2019 Oct 1;142:111544
pubmed: 31376717
Life Sci. 2021 Feb 1;266:118871
pubmed: 33309716
Drug Deliv. 2016 May;23(4):1291-305
pubmed: 26430913
Sci Rep. 2017 May 16;7(1):1991
pubmed: 28512335
Anal Bioanal Chem. 2014 Apr;406(9-10):2303-23
pubmed: 24566759
Antibodies (Basel). 2019 Mar 06;8(1):
pubmed: 31544828
Small. 2019 Apr;15(17):e1900935
pubmed: 30920730
ACS Nano. 2022 Feb 22;16(2):2345-2354
pubmed: 35040633
Anal Chem. 2018 Apr 3;90(7):4544-4551
pubmed: 29570270
Biosens Bioelectron. 2016 Mar 15;77:435-41
pubmed: 26453904
Mol Ther. 2016 Aug;24(7):1267-77
pubmed: 27125502
Analyst. 2021 Apr 26;146(8):2679-2688
pubmed: 33687386
Methods Mol Biol. 2018;1827:421-455
pubmed: 30196510
ACS Nano. 2019 Jan 22;13(1):706-717
pubmed: 30543397
Mikrochim Acta. 2018 Jul 11;185(8):372
pubmed: 29995191
Biomater Sci. 2020 May 21;8(10):2939-2954
pubmed: 32319481
Nanotechnology. 2020 Feb 21;31(9):095501
pubmed: 31703221
ACS Appl Mater Interfaces. 2020 Feb 26;12(8):9032-9040
pubmed: 31986004
Diagnostics (Basel). 2021 Jul 26;11(8):
pubmed: 34441278
Nano Lett. 2018 Jul 11;18(7):4086-4094
pubmed: 29927251
Nanomedicine. 2018 Aug;14(6):1891-1903
pubmed: 29885900
Sci Rep. 2017 Mar 21;7:45060
pubmed: 28322342
Biosens Bioelectron. 2016 Mar 15;77:1001-7
pubmed: 26547426
Pharmaceutics. 2020 Feb 22;12(2):
pubmed: 32098309
Bioorg Chem. 2021 Feb;107:104605
pubmed: 33421955
Int J Mol Sci. 2022 Jan 30;23(3):
pubmed: 35163550
Redox Biol. 2021 Jun;42:101908
pubmed: 33674250
Phys Biol. 2016 Dec 06;13(6):066010
pubmed: 27922830
Analyst. 2019 Aug 21;144(16):4917-4924
pubmed: 31313769
ACS Sens. 2019 Jul 26;4(7):1950-1956
pubmed: 31310098
Anal Biochem. 2019 Jul 15;577:89-97
pubmed: 31029676
Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3391-3400
pubmed: 30808736
Cancer Sci. 2017 Jul;108(7):1493-1503
pubmed: 28444967
J Mater Chem B. 2020 May 21;8(19):4310-4317
pubmed: 32329505
Cell Mol Life Sci. 2020 Mar;77(6):1059-1086
pubmed: 31637450
Biotechnol Lett. 2021 May;43(5):981-994
pubmed: 33515341
Genomics Proteomics Bioinformatics. 2012 Oct;10(5):246-53
pubmed: 23200134
Biosens Bioelectron. 2017 Jan 15;87:433-438
pubmed: 27589408