Biomarkers in Primary Focal Segmental Glomerulosclerosis in Optimal Diagnostic-Therapeutic Strategy.
biomarkers
glomerulonephritis
primary FSGS
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
08 Jun 2022
08 Jun 2022
Historique:
received:
18
04
2022
revised:
02
06
2022
accepted:
06
06
2022
entrez:
24
6
2022
pubmed:
25
6
2022
medline:
25
6
2022
Statut:
epublish
Résumé
Focal segmental glomerulosclerosis (FSGS) involves podocyte injury. In patients with nephrotic syndrome, progression to end-stage renal disease often occurs over the course of 5 to 10 years. The diagnosis is based on a renal biopsy. It is presumed that primary FSGS is caused by an unknown plasma factor that might be responsible for the recurrence of FSGS after kidney transplantation. The nature of circulating permeability factors is not explained and particular biological molecules responsible for inducing FSGS are still unknown. Several substances have been proposed as potential circulating factors such as soluble urokinase-type plasminogen activator receptor (suPAR) and cardiolipin-like-cytokine 1 (CLC-1). Many studies have also attempted to establish which molecules are related to podocyte injury in the pathogenesis of FSGS such as plasminogen activator inhibitor type-1 (PAI-1), angiotensin II type 1 receptors (AT1R), dystroglycan(DG), microRNAs, metalloproteinases (MMPs), forkheadbox P3 (FOXP3), and poly-ADP-ribose polymerase-1 (PARP1). Some biomarkers have also been studied in the context of kidney tissue damage progression: transforming growth factor-beta (TGF-β), human neutrophil gelatinase-associated lipocalin (NGAL), malondialdehyde (MDA), and others. This paper describes molecules that could potentially be considered as circulating factors causing primary FSGS.
Identifiants
pubmed: 35743361
pii: jcm11123292
doi: 10.3390/jcm11123292
pmc: PMC9225193
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Grant information: Wroclaw Medical University
ID : STM.C 160.20.069
Références
J Clin Apher. 2017 Dec;32(6):444-452
pubmed: 28370393
Clin Kidney J. 2015 Dec;8(6):708-15
pubmed: 26613029
Eur J Clin Invest. 2005 Apr;35(4):245-50
pubmed: 15816993
Nephrol Dial Transplant. 1997 Mar;12(3):418-26
pubmed: 9075118
Transl Res. 2008 Apr;151(4):217-23
pubmed: 18355769
J Biol Chem. 2010 Oct 29;285(44):34086-96
pubmed: 20739294
Dis Markers. 2013;34(5):357-62
pubmed: 23478276
Transplant Proc. 2020 Oct;52(8):2299-2304
pubmed: 32448653
Biochim Biophys Acta. 2010 Jul-Aug;1802(7-8):659-72
pubmed: 20388541
J Am Soc Nephrol. 2005 Nov;16(11):3211-21
pubmed: 16207831
J Clin Invest. 2001 Sep;108(6):807-16
pubmed: 11560950
Biomed Res Int. 2016;2016:1630365
pubmed: 27088082
Nat Rev Nephrol. 2015 Feb;11(2):76-87
pubmed: 25447132
Kidney Int. 2003 Nov;64(5):1715-21
pubmed: 14531804
Life Sci. 2021 Jul 15;277:119463
pubmed: 33862110
J Am Soc Nephrol. 2005 Oct;16(10):2941-52
pubmed: 16107576
Am J Physiol Renal Physiol. 2007 Mar;292(3):F905-11
pubmed: 17190907
J Biol Chem. 2011 Feb 25;286(8):6301-10
pubmed: 21149456
Prog Transplant. 2018 Jun;28(2):134-141
pubmed: 29798728
Kidney Int. 1996 Feb;49(2):461-9
pubmed: 8821830
BMC Nephrol. 2015 Jul 22;16:111
pubmed: 26198842
Nephrol Dial Transplant. 2007 Apr;22(4):1115-22
pubmed: 17205957
Clin J Am Soc Nephrol. 2010 Nov;5(11):2115-21
pubmed: 20966123
J Immunol. 1998 Aug 1;161(3):1371-9
pubmed: 9686600
Expert Opin Biol Ther. 2009 Jun;9(6):703-711
pubmed: 19426115
Nat Med. 2008 Aug;14(8):855-62
pubmed: 18660815
Pediatr Nephrol. 2011 Dec;26(12):2179-84
pubmed: 21720805
Pediatr Nephrol. 1997 Jun;11(3):334-6
pubmed: 9203185
J Clin Invest. 2003 Aug;112(3):379-88
pubmed: 12897205
Int J Mol Sci. 2019 Oct 11;20(20):
pubmed: 31614644
Crit Care. 2011;15(1):R63
pubmed: 21324198
Kidney Int Rep. 2020 Jul 23;5(10):1690-1699
pubmed: 33102961
Cells. 2020 May 05;9(5):
pubmed: 32380691
Kidney Int. 2002 Jan;61(1):90-5
pubmed: 11786088
Free Radic Biol Med. 2011 Nov 1;51(9):1774-88
pubmed: 21884784
Sci Rep. 2019 Sep 24;9(1):13783
pubmed: 31551522
Dis Markers. 2019 May 2;2019:1070495
pubmed: 31191741
Eur J Histochem. 2013 Nov 20;57(4):e35
pubmed: 24441188
J Nephrol. 2015 Feb;28(1):39-49
pubmed: 24756969
World J Hepatol. 2012 Dec 27;4(12):356-64
pubmed: 23355913
Transplant Proc. 2014 Oct;46(8):2636-9
pubmed: 25380883
Am J Pathol. 2007 Jun;170(6):1841-53
pubmed: 17525253
Pediatr Nephrol. 2006 Jun;21(6):800-6
pubmed: 16604373
EMBO J. 2000 Apr 17;19(8):1745-54
pubmed: 10775259
Nephrol Dial Transplant. 2003 Aug;18 Suppl 6:vi39-44
pubmed: 12953041
Nature. 2011 Jul 06;475(7354):106-9
pubmed: 21734707
Kidney Int. 2014 Mar;85(3):636-40
pubmed: 24402090
Pediatr Nephrol. 2013 Nov;28(11):2131-5
pubmed: 23793883
Clin J Am Soc Nephrol. 2008 May;3(3):665-73
pubmed: 18337554
Exp Biol Med (Maywood). 2011 May 1;236(5):614-20
pubmed: 21521713
Biochem J. 1996 Aug 15;318 ( Pt 1):1-14
pubmed: 8761444
Int J Nephrol Renovasc Dis. 2017 May 10;10:97-107
pubmed: 28546764
Kidney Int. 2014 Mar;85(3):641-8
pubmed: 24429394
Nat Med. 2008 Jan;14(1):55-63
pubmed: 18084301
J Renin Angiotensin Aldosterone Syst. 2005 Dec;6(3):138-44
pubmed: 16525944
J Am Soc Nephrol. 2018 Mar;29(3):759-774
pubmed: 29321142
Oncol Rep. 2014 Apr;31(4):1777-87
pubmed: 24535158
Clin Transplant. 2015 Jul;29(7):606-11
pubmed: 25973696
Ann Palliat Med. 2020 Sep;9(5):3187-3193
pubmed: 32921106
Neuron. 1991 Aug;7(2):197-208
pubmed: 1714745
J Neuropathol Exp Neurol. 2005 Apr;64(4):280-94
pubmed: 15835264
Am J Pathol. 2008 Feb;172(2):299-308
pubmed: 18202193
Cardiovasc Drug Rev. 2007 Fall;25(3):235-60
pubmed: 17919258
Pediatr Nephrol. 2018 Oct;33(10):1741-1750
pubmed: 29982877
Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4827-32
pubmed: 15051883
Am J Transplant. 2008 Jul;8(7):1423-33
pubmed: 18510637
Clin J Am Soc Nephrol. 2009 Nov;4(11):1747-53
pubmed: 19808230
Am J Kidney Dis. 2002 Apr;39(4):695-705
pubmed: 11920334
Clin Rheumatol. 2008 Feb;27(2):163-9
pubmed: 17646900
Kidney Int. 2004 Sep;66(3):898-904
pubmed: 15327378
Matrix Biol. 2000 Aug;19(4):309-17
pubmed: 10963991
Kidney Dis (Basel). 2019 Oct;5(4):239-246
pubmed: 31768381
J Am Soc Nephrol. 1999 Feb;10(2):271-80
pubmed: 10215326
Semin Thromb Hemost. 2017 Mar;43(2):169-177
pubmed: 27556351
Nat Rev Immunol. 2017 Nov;17(11):703-717
pubmed: 28757603
Mol Cell Biochem. 2006 Mar;284(1-2):9-17
pubmed: 16477388
Am J Nephrol. 2020;51(6):442-452
pubmed: 32348995
Front Med (Lausanne). 2018 Apr 16;5:98
pubmed: 29713631
J Clin Invest. 1990 Feb;85(2):541-9
pubmed: 1688888
Transplantation. 2013 Aug 27;96(4):394-9
pubmed: 23736353
Biochim Biophys Acta. 2010 Jan;1803(1):20-8
pubmed: 19374923
PLoS One. 2009 Sep 28;4(9):e7138
pubmed: 19784367
J Histochem Cytochem. 2011 Jun;59(6):601-14
pubmed: 21430262
Kidney Int Rep. 2021 Oct 30;7(1):68-77
pubmed: 35005315
Clin Transplant. 2019 Mar;33(3):e13487
pubmed: 30689221
Dis Markers. 2014;2014:192836
pubmed: 24719498
Nephrol Dial Transplant. 2002;17 Suppl 9:23-4
pubmed: 12386278
Am J Pathol. 2010 Sep;177(3):1356-64
pubmed: 20696779
J Virol. 2012 Feb;86(4):2067-78
pubmed: 22156524
Nephron Clin Pract. 2003;95(3):c100-4
pubmed: 14646370
PLoS One. 2011 Apr 20;6(4):e19080
pubmed: 21533062
Transl Res. 2008 Jun;151(6):288-92
pubmed: 18514139
N Engl J Med. 2013 Mar 7;368(10):971
pubmed: 23465122
Kidney Int. 1998 Dec;54(6):1843-9
pubmed: 9853248
Am J Pathol. 2011 Oct;179(4):1719-32
pubmed: 21839714
Nephrol Dial Transplant. 2002 Jul;17(7):1189-96
pubmed: 12105240
Mol Vis. 2011 Apr 06;17:854-63
pubmed: 21527993
J Am Soc Nephrol. 2012 Dec;23(12):2051-9
pubmed: 23138488
Kidney Int. 2013 Aug;84(2):366-72
pubmed: 23447064
J Intern Med. 2003 Sep;254(3):216-24
pubmed: 12930230
Kidney Int. 2005 Nov;68(5):2079-90
pubmed: 16221207
Am J Physiol Renal Physiol. 2011 Mar;300(3):F772-82
pubmed: 21159735
Korean J Intern Med. 2014 Mar;29(2):176-82
pubmed: 24648800
J Physiol Sci. 2015 Jan;65(1):105-11
pubmed: 25388944
Am J Pathol. 2000 May;156(5):1749-65
pubmed: 10793086
Mediators Inflamm. 2016;2016:8970291
pubmed: 27382192
Front Aging Neurosci. 2020 Aug 13;12:255
pubmed: 32903806
Plast Reconstr Surg. 2010 Dec;126(6):1899-1910
pubmed: 21124130
N Engl J Med. 2005 Feb 10;352(6):558-69
pubmed: 15703421
Biomed Pharmacother. 2018 Sep;105:83-94
pubmed: 29852393
Transplantation. 2020 Jan;104(1):54-60
pubmed: 31449183
Oxid Med Cell Longev. 2012;2012:856085
pubmed: 23213350
Cell Signal. 2002 Mar;14(3):183-9
pubmed: 11812645
Diagn Pathol. 2014 Feb 21;9:40
pubmed: 24559085
Crit Care Clin. 2021 Apr;37(2):385-398
pubmed: 33752862
Nat Med. 2013 Apr;19(4):481-7
pubmed: 23502960
Nephrol Dial Transplant. 2015 Jun;30(6):910-7
pubmed: 25170095
Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10513-8
pubmed: 18663219
Iran J Kidney Dis. 2012 Sep;6(5):355-60
pubmed: 22976261
PLoS One. 2010 Aug 25;5(8):e12400
pubmed: 20811645
J Am Soc Nephrol. 2000 Mar;11(3):403-412
pubmed: 10703664
Sci Rep. 2016 Nov 03;6:36118
pubmed: 27808277
Nephron. 2020;144(9):413-427
pubmed: 32721952
Transl Res. 2015 Oct;166(4):384-98
pubmed: 25843671
Kidney Int. 2011 Jul;80(2):154-64
pubmed: 21525855
Nephrol Dial Transplant. 2017 Apr 01;32(suppl_2):ii209-ii218
pubmed: 28339709
Transplantation. 2011 Jan 27;91(2):191-8
pubmed: 21157405
Kidney Int. 2015 Mar;87(3):564-74
pubmed: 25354239
BMC Nephrol. 2020 Jul 2;21(1):253
pubmed: 32615995
Microsc Res Tech. 2008 May;71(5):371-9
pubmed: 18300288
Am J Physiol Renal Physiol. 2005 Feb;288(2):F387-98
pubmed: 15494543
J Clin Invest. 1985 Aug;76(2):612-9
pubmed: 2993362
Transplant Proc. 2018 Jul - Aug;50(6):1847-1849
pubmed: 30056913
Kidney Int. 2009 Jan;75(2):227-34
pubmed: 18818682
Cell. 1994 Jun 3;77(5):675-86
pubmed: 8205617
Nat Med. 2011 Jul 31;17(8):952-60
pubmed: 21804539