Biomarkers Predictive of Metabolic Syndrome and Cardiovascular Disease in Childhood Cancer Survivors.
cancer survivors
cardiovascular disease
chemotherapy toxicity
childhood cancer
metabolic syndrome
obesity
radiotherapy toxicity
Journal
Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269
Informations de publication
Date de publication:
27 May 2022
27 May 2022
Historique:
received:
17
04
2022
revised:
23
05
2022
accepted:
25
05
2022
entrez:
24
6
2022
pubmed:
25
6
2022
medline:
25
6
2022
Statut:
epublish
Résumé
The improvement in childhood cancer treatments resulted in a marked improvement in the survival of pediatric cancer patients. However, as survival increased, it was also possible to observe the long-term side effects of cancer therapies. Among these, metabolic syndrome is one of the most frequent long-term side effects, and causes high mortality and morbidity. Consequently, it is necessary to identify strategies that allow for early diagnosis. In this review, the pathogenetic mechanisms of metabolic syndrome and the potential new biomarkers that can facilitate its diagnosis in survivors of pediatric tumors are analyzed.
Identifiants
pubmed: 35743665
pii: jpm12060880
doi: 10.3390/jpm12060880
pmc: PMC9225298
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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