In Vivo Verification of Treatment Source Dwell Times in Brachytherapy of Postoperative Endometrial Carcinoma: A Feasibility Study.

brachytherapy endometrial carcinoma in vivo dosimetry plastic scintillator dosimeter treatment verification

Journal

Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269

Informations de publication

Date de publication:
31 May 2022
Historique:
received: 30 03 2022
revised: 24 05 2022
accepted: 28 05 2022
entrez: 24 6 2022
pubmed: 25 6 2022
medline: 25 6 2022
Statut: epublish

Résumé

(1) Background: In brachytherapy, there are still many manual procedures that can cause adverse events which can be detected with in vivo dosimetry systems. Plastic scintillator dosimeters (PSD) have interesting properties to achieve this objective such as real-time reading, linearity, repeatability, and small size to fit inside brachytherapy catheters. The purpose of this study was to evaluate the performance of a PSD in postoperative endometrial brachytherapy in terms of source dwell time accuracy. (2) Methods: Measurements were carried out in a PMMA phantom to characterise the PSD. Patient measurements in 121 dwell positions were analysed to obtain the differences between planned and measured dwell times. (3) Results: The repeatability test showed a relative standard deviation below 1% for the measured dwell times. The relative standard deviation of the PSD sensitivity with accumulated absorbed dose was lower than 1.2%. The equipment operated linearly in total counts with respect to absorbed dose and also in count rate versus absorbed dose rate. The mean (standard deviation) of the absolute differences between planned and measured dwell times in patient treatments was 0.0 (0.2) seconds. (4) Conclusions: The PSD system is useful as a quality assurance tool for brachytherapy treatments.

Identifiants

pubmed: 35743696
pii: jpm12060911
doi: 10.3390/jpm12060911
pmc: PMC9224704
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Antonio Herreros (A)

Fonaments Clínics Department, University of Barcelona, 08036 Barcelona, Spain.
Radiation Oncology Department, Hospital Clínic Universitari, 08036 Barcelona, Spain.

José Pérez-Calatayud (J)

Radiation Oncology Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Radiation Oncology Department, Hospital Clinica Benidorm, 03501 Alicante, Spain.

Facundo Ballester (F)

IRIMED, IIS-La Fe-Universitat de Valencia (UV), 46100 Burjassot, Spain.

Jose Barrera-Gómez (J)

Mathematics Department, Autonomous University of Barcelona, 08193 Bellatera, Spain.

Rosa Abellana (R)

Fonaments Clínics Department, University of Barcelona, 08036 Barcelona, Spain.

Joana Melo (J)

NU-RISE LDA, PCI-Creative Science Park, 3830-352 Ilhavo, Portugal.

Luis Moutinho (L)

NU-RISE LDA, PCI-Creative Science Park, 3830-352 Ilhavo, Portugal.

Luca Tagliaferri (L)

U.O.C. Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.

Ángeles Rovirosa (Á)

Fonaments Clínics Department, University of Barcelona, 08036 Barcelona, Spain.
Radiation Oncology Department, Hospital Clínic Universitari, 08036 Barcelona, Spain.
Gynecologic Cancer Unit, Hospital Clínic Universitari, 08036 Barcelona, Spain.

Classifications MeSH