Nontarget and Out-of-Field Doses from Electron Beam Radiotherapy.
electron beams
nontarget doses
out-of-field doses
radiation scattering
Journal
Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444
Informations de publication
Date de publication:
08 Jun 2022
08 Jun 2022
Historique:
received:
24
04
2022
revised:
03
06
2022
accepted:
06
06
2022
entrez:
24
6
2022
pubmed:
25
6
2022
medline:
25
6
2022
Statut:
epublish
Résumé
In clinical radiotherapy, the most important aspects are the dose distribution in the target volume and healthy organs, including out-of-field doses in the body. Compared to photon beam radiation, dose distribution in electron beam radiotherapy has received much less attention, mainly due to the limited range of electrons in tissues. However, given the growing use of electron intraoperative radiotherapy and FLASH, further study is needed. Therefore, in this study, we determined out-of-field doses from an electron beam in a phantom model using two dosimetric detectors (diode E and cylindrical Farmer-type ionizing chamber) for electron energies of 6 MeV, 9 MeV and 12 MeV. We found a clear decrease in out-of-field doses as the distance from the field edge and depth increased. The out-of-field doses measured with the diode E were lower than those measured with the Farmer-type ionization chamber at each depth and for each electron energy level. The out-of-field doses increased when higher energy megavoltage electron beams were used (except for 9 MeV). The out-of-field doses at shallow depths (1 or 2 cm) declined rapidly up to a distance of 3 cm from the field edge. This study provides valuable data on the deposition of radiation energy from electron beams outside the irradiation field.
Identifiants
pubmed: 35743890
pii: life12060858
doi: 10.3390/life12060858
pmc: PMC9225003
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : National Science Centre of Poland
ID : 2015/19/B/NZ7/03811
Références
Phys Med Biol. 2012 Aug 21;57(16):5059-74
pubmed: 22836598
Phys Med Biol. 1999 Nov;44(11):2803-20
pubmed: 10588286
Phys Med. 2017 Oct;42:239-246
pubmed: 28392312
Med Phys. 2001 Jul;28(7):1352-8
pubmed: 11488565
Cancer Radiother. 2017 Aug;21(5):345-351
pubmed: 28433589
Cancer Radiother. 2017 Aug;21(5):352-357
pubmed: 28623063
Phys Med Biol. 2006 Jun 21;51(12):N231-40
pubmed: 16757855
J Appl Clin Med Phys. 2016 Jul 08;17(4):442-455
pubmed: 27455499
Rep Pract Oncol Radiother. 2019 Sep-Oct;24(5):409-420
pubmed: 31333335
Acta Radiol Oncol. 1980;19(3):199-207
pubmed: 6257038
Phys Med Biol. 2003 Aug 7;48(15):2493-507
pubmed: 12953911
Int J Breast Cancer. 2014;2014:472516
pubmed: 25258684
Rep Pract Oncol Radiother. 2020 Jul-Aug;25(4):470-478
pubmed: 32494222
Sci Transl Med. 2014 Jul 16;6(245):245ra93
pubmed: 25031268
Med Phys. 2009 Jul;36(7):3239-79
pubmed: 19673223
Rep Pract Oncol Radiother. 2021 Feb 25;26(1):50-58
pubmed: 33948302
Phys Med Biol. 2006 Jul 7;51(13):R455-89
pubmed: 16790918
Phys Med Biol. 2010 Apr 21;55(8):2155-66
pubmed: 20305334
Life (Basel). 2022 Apr 23;12(5):
pubmed: 35629296
Med Phys. 2001 Dec;28(12):2527-34
pubmed: 11797957
Phys Med Biol. 2017 Nov 13;62(23):9039-9053
pubmed: 29048329
Australas Phys Eng Sci Med. 2018 Sep;41(3):647-655
pubmed: 29943310
J Appl Clin Med Phys. 2010 Jun 15;11(3):3105
pubmed: 20717080
Phys Med. 2013 Jun;29(4):388-96
pubmed: 22771332
Med Phys. 2017 Oct;44(10):e391-e429
pubmed: 28688159
Med Phys. 1990 Jul-Aug;17(4):715-9
pubmed: 2215419
Front Oncol. 2020 Jul 07;10:989
pubmed: 32733794
Phys Med Biol. 2000 Nov;45(11):3159-70
pubmed: 11098896
J Appl Clin Med Phys. 2015 Nov 08;16(6):435–448
pubmed: 26699572