Enhanced Antibiotic Tolerance of an

CAUTI antibiotic tolerance biofilms infections interactions multispecies

Journal

Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893

Informations de publication

Date de publication:
13 Jun 2022
Historique:
received: 29 04 2022
revised: 02 06 2022
accepted: 09 06 2022
entrez: 24 6 2022
pubmed: 25 6 2022
medline: 25 6 2022
Statut: epublish

Résumé

Catheter-associated urinary tract infections (CAUTI) are a common clinical concern as they can lead to severe, persistent infections or bacteremia in long-term catheterized patients. This type of CAUTI is difficult to eradicate, as they are caused by multispecies biofilms that may have reduced susceptibility to antibiotics. Many new strategies to tackle CAUTI have been proposed in the past decade, including antibiotic combination treatments, surface modification and probiotic usage. However, those strategies were mainly assessed on mono- or dual-species biofilms that hardly represent the long-term CAUTI cases where, normally, 2-4 or even more species can be involved. We developed a four-species

Identifiants

pubmed: 35744727
pii: microorganisms10061207
doi: 10.3390/microorganisms10061207
pmc: PMC9227968
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Lundbeck Foundation
ID : R324-2019-1775

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Auteurs

Jiapeng Hou (J)

Section of Microbiology, Department of Biology, University of Copenhagen, Universitetsparken 15, 2100 Copenhagen, Denmark.

Lutian Wang (L)

Section of Microbiology, Department of Biology, University of Copenhagen, Universitetsparken 15, 2100 Copenhagen, Denmark.

Martin Alm (M)

Biomodics ApS, Fjeldhammervej 15, 2610 Rødovre, Denmark.

Peter Thomsen (P)

Biomodics ApS, Fjeldhammervej 15, 2610 Rødovre, Denmark.

Tor Monsen (T)

Department of Clinical Microbiology, Umeå University, 901 85 Umeå, Sweden.

Madeleine Ramstedt (M)

Department of Chemistry, Umeå University, 901 87 Umeå, Sweden.

Mette Burmølle (M)

Section of Microbiology, Department of Biology, University of Copenhagen, Universitetsparken 15, 2100 Copenhagen, Denmark.

Classifications MeSH