Statin prescription and CV risk assessment in adult psychiatric outpatients with intellectual disability.
cardiovascular diseases
intellectual disability
primary prevention
risk stratification
Journal
The British journal of cardiology
ISSN: 1753-4313
Titre abrégé: Br J Cardiol
Pays: England
ID NLM: 9503762
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
24
6
2022
pubmed:
25
6
2022
medline:
25
6
2022
Statut:
epublish
Résumé
We performed a single-centre study to assess the risk of cardiovascular disease (CVD) in psychiatry outpatients with intellectual disability (ID) using the QRISK-3 score. There were 143 patients known to the ID psychiatry clinic enrolled. Of these, 28 (19.6%) had elevated CVD risk - defined as 10-year risk of heart attack or stroke of ≥10%. Of these, 57.1% were not prescribed statin therapy, which - after lifestyle measures - is recommended by National Institute for Health and Care Excellence (NICE) guidelines. The mean QRISK-3 score was 6.31% (95% confidence interval [CI] 4.84 to 7.78), with a relative risk of 3.50 (95%CI 2.34 to 4.67) compared with matched controls. The high CVD risk identified in this study supports routine CVD risk assessment and management in adult outpatients with ID. Appropriate lifestyle measures and statin therapy could help reduce the excess CVD-related morbidity and mortality in ID patients.
Identifiants
pubmed: 35747067
doi: 10.5837/bjc.2021.049
pii: bjc.2021.049
pmc: PMC9063702
doi:
Types de publication
Journal Article
Langues
eng
Pagination
49Informations de copyright
Copyright © 2021 Medinews (Cardiology) Limited.
Déclaration de conflit d'intérêts
Conflicts of interest None declared.
Références
World Psychiatry. 2017 Jun;16(2):163-180
pubmed: 28498599
BMJ. 2017 May 23;357:j2099
pubmed: 28536104
BMJ Open. 2016 Dec 5;6(12):e013116
pubmed: 27920085
Dialogues Clin Neurosci. 2018 Mar;20(1):31-40
pubmed: 29946209
Br J Psychiatry. 2007 Jan;190:27-35
pubmed: 17197653
Ment Retard Dev Disabil Res Rev. 2006;12(1):3-12
pubmed: 16435328
J Am Coll Cardiol. 2019 Sep 10;74(10):e177-e232
pubmed: 30894318
Res Dev Disabil. 2012 Nov-Dec;33(6):1722-31
pubmed: 22699246
Br J Gen Pract. 2016 Apr;66(645):e264-70
pubmed: 26906630
Lancet. 2014 Mar 8;383(9920):889-95
pubmed: 24332307