BMI as a predictor of high fasting blood glucose among people living with HIV in the Asia-Pacific region.
Asia-Pacific
BMI
HIV
high fasting blood glucose
Journal
HIV medicine
ISSN: 1468-1293
Titre abrégé: HIV Med
Pays: England
ID NLM: 100897392
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
received:
22
09
2021
accepted:
23
05
2022
pmc-release:
01
02
2024
pubmed:
25
6
2022
medline:
16
2
2023
entrez:
24
6
2022
Statut:
ppublish
Résumé
Non-Asian body mass index (BMI) classifications are commonly used as a risk factor for high fasting blood glucose (FBG). We investigated the incidence and factors associated with high FBG among people living with HIV in the Asia-Pacific region, using a World Health Organization BMI classification specific to Asian populations. This study included people living with HIV enrolled in a longitudinal cohort study from 2003 to 2019, receiving antiretroviral therapy (ART), and without prior tuberculosis. BMI at ART initiation was categorized using Asian BMI classifications: underweight (<18.5 kg/m A total of 3939 people living with HIV (63% male) were included. In total, 50% had a BMI in the normal weight range, 23% were underweight, 13% were overweight, and 14% were obese. Median age at ART initiation was 34 years (interquartile range 29-41). Overall, 8% had a high FBG, with an incidence rate of 1.14 per 100 person-years. Factors associated with an increased hazard of high FBG included being obese (≥25 kg/m People living with HIV with BMI >25 kg/m
Sections du résumé
BACKGROUND
Non-Asian body mass index (BMI) classifications are commonly used as a risk factor for high fasting blood glucose (FBG). We investigated the incidence and factors associated with high FBG among people living with HIV in the Asia-Pacific region, using a World Health Organization BMI classification specific to Asian populations.
METHODS
This study included people living with HIV enrolled in a longitudinal cohort study from 2003 to 2019, receiving antiretroviral therapy (ART), and without prior tuberculosis. BMI at ART initiation was categorized using Asian BMI classifications: underweight (<18.5 kg/m
RESULTS
A total of 3939 people living with HIV (63% male) were included. In total, 50% had a BMI in the normal weight range, 23% were underweight, 13% were overweight, and 14% were obese. Median age at ART initiation was 34 years (interquartile range 29-41). Overall, 8% had a high FBG, with an incidence rate of 1.14 per 100 person-years. Factors associated with an increased hazard of high FBG included being obese (≥25 kg/m
CONCLUSION
People living with HIV with BMI >25 kg/m
Identifiants
pubmed: 35748404
doi: 10.1111/hiv.13351
pmc: PMC9789206
mid: NIHMS1841321
doi:
Substances chimiques
Blood Glucose
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
139-152Subventions
Organisme : FIC NIH HHS
ID : D43 TW009590
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI069907
Pays : United States
Informations de copyright
© 2022 British HIV Association.
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