Trajectories of physical functioning among US adults with cognitive impairment.
dementia
group-based trajectory models
mild cognitive impairment
older people
physical functioning
Journal
Age and ageing
ISSN: 1468-2834
Titre abrégé: Age Ageing
Pays: England
ID NLM: 0375655
Informations de publication
Date de publication:
01 06 2022
01 06 2022
Historique:
received:
28
12
2021
entrez:
25
6
2022
pubmed:
26
6
2022
medline:
29
6
2022
Statut:
ppublish
Résumé
physical functioning impairment is common among persons with cognitive impairment, but little is known about physical functioning trajectories across the US population or how trajectories may differ among persons with dementia and mild cognitive impairment (MCI). to examine trajectories of physical functioning among persons with MCI and dementia in the USA. we used data from the National Health and Aging Trends study (NHATS) 2011-18. Physical functioning was assessed using the NHATS Expanded Short Physical Performance Battery. the 661 individuals with MCI and 980 individuals with dementia were included in this study. we applied group-based trajectory models to identify latent groups and estimate their trajectories. Multinomial logistic regressions were applied to examine relationships between sociodemographic and health characteristics and trajectory group memberships. both MCI- and dementia-specific trajectories differed at baseline levels and declined at varying rates across groups. Approximately, 78.43% of persons with MCI were in trajectories with a moderate rate of decline, with only 9.75% in a trajectory with good physical function and 11.82% with poor physical function without as much change over time. Among persons with dementia, approximately 81.4% experienced moderate or fast declines, and 18.52% with virtually no functional ability remained at this same low level. Worse physical functioning trajectories were found among persons who were females, Blacks, with at least four comorbidities, and among persons who had a low socioeconomic status. persons with both dementia and MCI experienced steady declines in physical functioning. Socioeconomically disadvantaged groups have worse physical functioning trajectories.
Sections du résumé
BACKGROUND
physical functioning impairment is common among persons with cognitive impairment, but little is known about physical functioning trajectories across the US population or how trajectories may differ among persons with dementia and mild cognitive impairment (MCI).
OBJECTIVE
to examine trajectories of physical functioning among persons with MCI and dementia in the USA.
DESIGN
we used data from the National Health and Aging Trends study (NHATS) 2011-18. Physical functioning was assessed using the NHATS Expanded Short Physical Performance Battery.
PARTICIPANTS
the 661 individuals with MCI and 980 individuals with dementia were included in this study.
METHODS
we applied group-based trajectory models to identify latent groups and estimate their trajectories. Multinomial logistic regressions were applied to examine relationships between sociodemographic and health characteristics and trajectory group memberships.
RESULTS
both MCI- and dementia-specific trajectories differed at baseline levels and declined at varying rates across groups. Approximately, 78.43% of persons with MCI were in trajectories with a moderate rate of decline, with only 9.75% in a trajectory with good physical function and 11.82% with poor physical function without as much change over time. Among persons with dementia, approximately 81.4% experienced moderate or fast declines, and 18.52% with virtually no functional ability remained at this same low level. Worse physical functioning trajectories were found among persons who were females, Blacks, with at least four comorbidities, and among persons who had a low socioeconomic status.
CONCLUSIONS
persons with both dementia and MCI experienced steady declines in physical functioning. Socioeconomically disadvantaged groups have worse physical functioning trajectories.
Identifiants
pubmed: 35751871
pii: 6615423
doi: 10.1093/ageing/afac139
pmc: PMC9233517
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIA NIH HHS
ID : P30 AG021342
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Organisme : NIA NIH HHS
ID : R21AG074238-01
Pays : United States
Informations de copyright
© The Author(s) 2022. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.
Références
Int J Epidemiol. 2019 Aug 1;48(4):1044-1045g
pubmed: 31237935
J Am Geriatr Soc. 2019 Jan;67(1):37-42
pubmed: 30460975
Clin Geriatr Med. 2002 May;18(2):159-73
pubmed: 12180241
Ann Am Thorac Soc. 2019 Apr;16(4):471-477
pubmed: 30571923
J Am Geriatr Soc. 1989 Dec;37(12):1117-21
pubmed: 2592718
Alzheimer Dis Assoc Disord. 2016 Jan-Mar;30(1):60-6
pubmed: 25886717
Epidemiol Rev. 2013;35:33-50
pubmed: 23349427
SSM Popul Health. 2020 Mar 31;11:100577
pubmed: 32300635
Lancet. 2020 Aug 8;396(10248):413-446
pubmed: 32738937
Curr Opin Psychiatry. 2019 Mar;32(2):123-129
pubmed: 30557268
BMC Geriatr. 2019 Jul 2;19(1):181
pubmed: 31266451
J Adv Nurs. 2009 May;65(5):922-33
pubmed: 19291191
J Gerontol A Biol Sci Med Sci. 2002 Aug;57(8):M523-31
pubmed: 12145367
Am J Geriatr Psychiatry. 2001 Spring;9(2):102-12
pubmed: 11316615
Arch Neurol. 2008 Jan;65(1):108-11
pubmed: 18195147
PLoS One. 2012;7(12):e53278
pubmed: 23300906
Gerontologist. 1989 Dec;29(6):804-7
pubmed: 2516001
J Gerontol. 1992 Mar;47(2):S88-95
pubmed: 1538080
J Gerontol A Biol Sci Med Sci. 2013 Aug;68(8):929-37
pubmed: 23250002
J Aging Health. 2017 Mar;29(2):289-309
pubmed: 26965083
Am J Epidemiol. 1988 Nov;128(5):1084-101
pubmed: 3189282
J Gerontol. 1994 Mar;49(2):M85-94
pubmed: 8126356
Annu Rev Clin Psychol. 2010;6:109-38
pubmed: 20192788
Int J Nurs Pract. 2015 Dec;21(6):813-9
pubmed: 24758279
J Physiother. 2020 Jan;66(1):9-18
pubmed: 31843427
J Gerontol A Biol Sci Med Sci. 2017 Feb;72(2):251-258
pubmed: 27129917
J Stroke Cerebrovasc Dis. 2015 Dec;24(12):2860-5
pubmed: 26411693
Age Ageing. 2016 May;45(3):382-8
pubmed: 26892339
J Am Geriatr Soc. 1984 Jan;32(1):49-55
pubmed: 6690576
PLoS One. 2009;4(5):e5521
pubmed: 19436724
J Aging Health. 2020 Oct;32(9):1133-1144
pubmed: 31789070
J Gerontol A Biol Sci Med Sci. 2010 Mar;65(3):300-6
pubmed: 19789197
J Am Geriatr Soc. 1997 Jan;45(1):92-100
pubmed: 8994496
Annu Rev Public Health. 1996;17:25-46
pubmed: 8724214
Chest. 2011 Aug;140(2):425-432
pubmed: 21330381