Development and validation of a risk-of-bias tool for assessing in vitro studies conducted in dentistry: The QUIN.


Journal

The Journal of prosthetic dentistry
ISSN: 1097-6841
Titre abrégé: J Prosthet Dent
Pays: United States
ID NLM: 0376364

Informations de publication

Date de publication:
22 Jun 2022
Historique:
received: 16 02 2022
revised: 23 05 2022
accepted: 23 05 2022
entrez: 25 6 2022
pubmed: 26 6 2022
medline: 26 6 2022
Statut: aheadofprint

Résumé

Systematic reviews and meta-analyses have emerged as forerunners of evidence-based dentistry, but assessing the quality of the available research is essential so that it can be applied to clinical practice. While a wide variety of risk-of-bias tools are available, each specifically developed for different study designs, a comprehensive tool exclusively framed to assess the quality of in vitro dental studies is lacking. The purpose of this study was to develop and validate a tool to evaluate the quality and risk of bias of in vitro dental studies. A Delphi panel was established to conceptualize and develop the Quality Assessment Tool For In Vitro Studies (QUIN Tool). The tool was evaluated by using content validity and reliability testing methods. The QUIN Tool includes 12 points along with scoring and grading options to allow clinicians to evaluate the quality of in vitro studies. This tool shows good content validity and reliability. The QUIN Tool is user-friendly, efficient, and effective for evaluating the risk of bias of in vitro studies.

Identifiants

pubmed: 35752496
pii: S0022-3913(22)00345-6
doi: 10.1016/j.prosdent.2022.05.019
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2022 Editorial Council for The Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

Auteurs

Vidhi H Sheth (VH)

Postgraduate student, Department of Prosthodontics and Crown & Bridge, T. P. C. T.'s Terna Dental College, Navi Mumbai, India. Electronic address: shethvidhi@gmail.com.

Naisargi P Shah (NP)

Professor and Head of Department, Department of Prosthodontics and Crown & Bridge, T. P. C. T.'s Terna Dental College, Navi Mumbai, India.

Romi Jain (R)

Professor and Head of Department, Department of Public Health Dentistry, T. P. C. T.'s Terna Dental College, Navi Mumbai, India.

Nikhil Bhanushali (N)

Reader, Department of Public Health Dentistry, T. P. C. T.'s Terna Dental College, Navi Mumbai, India.

Vishrut Bhatnagar (V)

Reader, Department of Prosthodontics and Crown & Bridge, T. P. C. T.'s Terna Dental College, Navi Mumbai, India.

Classifications MeSH