Key recommendations from the 2021 "inclusion of older adults in clinical research" workshop.

Clinical trials inclusion older adults

Journal

Journal of clinical and translational science
ISSN: 2059-8661
Titre abrégé: J Clin Transl Sci
Pays: England
ID NLM: 101689953

Informations de publication

Date de publication:
2022
Historique:
received: 11 10 2021
revised: 22 12 2021
accepted: 30 12 2021
entrez: 27 6 2022
pubmed: 28 6 2022
medline: 28 6 2022
Statut: epublish

Résumé

Older adults are often underrepresented in clinical research, even though older adults are major consumers of novel therapies. We present major themes and recommendations from the 2021 "Inclusion of Older Adults in Clinical Research" Workshop, convened by the Clinical and Translational Science Award (CTSA) Inclusion of Older Adults as a Model for Special Populations Workgroup and the Research Centers Collaborative Network (RCCN). The goal of this workshop was to develop strategies to assist the research community in increasing the inclusion of older adults in clinical research. Major identified barriers include historical lack of federal guidelines, ageist biases and stereotypes, and lack of recruitment and retention techniques or infrastructure focused on older adults. Three key recommendations emerged: 1) engaging with the policymaking process to further promote inclusion; 2) using the CTSA Workgroup Presentation Materials Library and other resources to overcome ageism, and 3) building institutional capacity to support age inclusion.

Identifiants

pubmed: 35754432
doi: 10.1017/cts.2022.1
pii: S2059866122000012
pmc: PMC9161040
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e55

Subventions

Organisme : NIA NIH HHS
ID : R25 AG060910
Pays : United States
Organisme : NIA NIH HHS
ID : U24 AG058556
Pays : United States
Organisme : NIA NIH HHS
ID : K23 AG053429
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG059988
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG059302
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR003098
Pays : United States
Organisme : NIA NIH HHS
ID : K01 AG070107
Pays : United States
Organisme : NIMHD NIH HHS
ID : U54 MD000538
Pays : United States
Organisme : NIA NIH HHS
ID : T32 AG066598
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG076834
Pays : United States
Organisme : NIA NIH HHS
ID : K23 AG073618
Pays : United States
Organisme : NHLBI NIH HHS
ID : K23 HL140132
Pays : United States

Informations de copyright

© The Author(s) 2022.

Déclaration de conflit d'intérêts

The authors have no conflicts of interest to declare.

Références

J Appl Gerontol. 2016 Oct;35(10):1058-76
pubmed: 25669876
J Am Heart Assoc. 2021 Apr 6;10(7):e019707
pubmed: 33754796
Implement Sci. 2015 Nov 04;10:155
pubmed: 26537706
JAMA Intern Med. 2020 Nov 1;180(11):1533-1534
pubmed: 32897305
J Am Geriatr Soc. 2019 Feb;67(2):218-222
pubmed: 30693958
Nurse Res. 2007;14(4):64-73
pubmed: 17702144
Adm Policy Ment Health. 2011 Mar;38(2):65-76
pubmed: 20957426
Stat Med. 2015 Aug 15;34(18):2602-17
pubmed: 25872751
J Am Geriatr Soc. 2012 Mar;60(3):413-9
pubmed: 22288835
Trans Am Clin Climatol Assoc. 2012;123:167-72; discussion 172-4
pubmed: 23303983
J Geriatr Cardiol. 2017 Apr;14(4):223-232
pubmed: 28663759
J Am Geriatr Soc. 2019 Feb;67(2):342-346
pubmed: 30693952
JAMA. 2011 Dec 28;306(24):2670-2
pubmed: 22203536
J Clin Oncol. 2018 Aug 1;36(22):2326-2347
pubmed: 29782209
JAMA. 2021 Oct 26;326(16):1627-1629
pubmed: 34499725
JAMA. 2018 Oct 16;320(15):1535-1536
pubmed: 30326521
BMC Med. 2018 Feb 28;16(1):29
pubmed: 29490655

Auteurs

Darina V Petrovsky (DV)

Rutgers University, New Brunswick, NJ, USA.

Lan N Ðoàn (LN)

New York University Grossman School of Medicine, New York, NY, USA.

Maria Loizos (M)

Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Rachel O'Conor (R)

Northwestern University, Evanston, IL, USA.

Micah Prochaska (M)

University of Chicago, Chicago, IL, USA.

Mazie Tsang (M)

University of California, San Francisco, CA, USA.

Rachel Hopman-Droste (R)

Pearson, London, UK.

Tara C Klinedinst (TC)

University of Pittsburgh, Pittsburgh, PA, USA.

Aarti Mathur (A)

Johns Hopkins University, Baltimore, MD, USA.

Karen Bandeen-Roche (K)

Johns Hopkins University, Baltimore, MD, USA.

Odette van der Willik (O)

American Federation for Aging Research, New York, NY, USA.

Stephen B Kritchevsky (SB)

Wake Forest School of Medicine, Winston-Salem, NC, USA.

Classifications MeSH