Using Remotely Supervised At-Home TES for Enhancing Mental Resilience.
at-home TES
major depressive disorder (MDD)
mental resilience
noninvasive brain stimulation (NIBS)
relapse prevention
transcranial direct current stimulation (tDCS)
transcranial electrical stimulation (TES)
Journal
Frontiers in human neuroscience
ISSN: 1662-5161
Titre abrégé: Front Hum Neurosci
Pays: Switzerland
ID NLM: 101477954
Informations de publication
Date de publication:
2022
2022
Historique:
received:
17
12
2021
accepted:
11
04
2022
entrez:
27
6
2022
pubmed:
28
6
2022
medline:
28
6
2022
Statut:
epublish
Résumé
We are in the midst of a mental health crisis with major depressive disorder being the most prevalent among mental health disorders and up to 30% of patients not responding to first-line treatments. Noninvasive Brain Stimulation (NIBS) techniques have proven to be effective in treating depression. However, there is a fundamental problem of scale. Currently, any type of NIBS treatment requires patients to repeatedly visit a clinic to receive brain stimulation by trained personnel. This is an often-insurmountable barrier to both patients and healthcare providers in terms of time and cost. In this perspective, we assess to what extent Transcranial Electrical Stimulation (TES) might be administered with remote supervision in order to address this scaling problem and enable neuroenhancement of mental resilience at home. Social, ethical, and technical challenges relating to hardware- and software-based solutions are discussed alongside the risks of stimulation under- or over-use. Solutions to provide users with a safe and transparent ongoing assessment of aptitude, tolerability, compliance, and/or misuse are proposed, including standardized training, eligibility screening, as well as compliance and side effects monitoring. Looking into the future, such neuroenhancement could be linked to prevention systems which combine home-use TES with digital sensor and mental monitoring technology to index decline in mental wellbeing and avoid relapse. Despite the described social, ethical legal, and technical challenges, the combination of remotely supervised, at-home TES setups with dedicated artificial intelligence systems could be a powerful weapon to combat the mental health crisis by bringing personalized medicine into people's homes.
Identifiants
pubmed: 35754763
doi: 10.3389/fnhum.2022.838187
pmc: PMC9218567
doi:
Types de publication
Journal Article
Langues
eng
Pagination
838187Informations de copyright
Copyright © 2022 Paneva, Leunissen, Schuhmann, de Graaf, Jønsson, Onarheim and Sack.
Déclaration de conflit d'intérêts
BO is the Founder and CEO of PlatoScience ApS, Copenhagen, Denmark. MJ is the Research Manager at PlatoScience ApS. AS is scientific advisor for PlatoScience ApS. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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