The quantum dot


Journal

Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951

Informations de publication

Date de publication:
07 Jun 2022
Historique:
received: 11 12 2021
accepted: 04 05 2022
entrez: 27 6 2022
pubmed: 28 6 2022
medline: 28 6 2022
Statut: epublish

Résumé

Förster resonance energy transfer (FRET) is a widely used and ideal transduction modality for fluorescent based biosensors as it offers high signal to noise with a visibly detectable signal. While intense efforts are ongoing to improve the limit of detection and dynamic range of biosensors based on biomolecule optimization, the selection of and relative location of the dye remains understudied. Herein, we describe a combined experimental and computational study to systematically compare the nature of the dye,

Identifiants

pubmed: 35756504
doi: 10.1039/d1sc06921g
pii: d1sc06921g
pmc: PMC9172442
doi:

Types de publication

Journal Article

Langues

eng

Pagination

6715-6731

Subventions

Organisme : NIBIB NIH HHS
ID : R01 EB029795
Pays : United States

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

The authors are inventors on a patent filed and owned by Boston University describing the TF–DNA biosensor. The patent is available for licensing.

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Auteurs

Chloé Grazon (C)

Department of Chemistry, Boston University Boston MA 02215 USA chloe.grazon@u-bordeaux.fr mgrin@bu.edu.
University Bordeaux, CNRS, Bordeaux INP, LCPO, UMR 5629 F-33600 Pessac France sebastien.lecommandoux@enscbp.fr.
University Bordeaux, CNRS, Bordeaux INP, ISM, UMR 5255 F-33400 Talence France.

Margaret Chern (M)

Division of Materials Science and Engineering, Boston University Boston MA 02215 USA margaret.chern@gmail.com aldennis@bu.edu.

Patrick Lally (P)

Department of Biomedical Engineering, Boston University Boston MA 02215 USA plally@bu.edu canvasback@gmail.com catherin@bu.edu.

R C Baer (RC)

Department of Microbiology, Boston University Boston MA 02118 USA rcbaer@gmail.com jgalag@bu.edu.
National Emerging Infectious Diseases Laboratories, Boston University Boston MA 02118 USA.

Andy Fan (A)

Department of Biomedical Engineering, Boston University Boston MA 02215 USA plally@bu.edu canvasback@gmail.com catherin@bu.edu.

Sébastien Lecommandoux (S)

University Bordeaux, CNRS, Bordeaux INP, LCPO, UMR 5629 F-33600 Pessac France sebastien.lecommandoux@enscbp.fr.

Catherine Klapperich (C)

Department of Biomedical Engineering, Boston University Boston MA 02215 USA plally@bu.edu canvasback@gmail.com catherin@bu.edu.

Allison M Dennis (AM)

Division of Materials Science and Engineering, Boston University Boston MA 02215 USA margaret.chern@gmail.com aldennis@bu.edu.
Department of Biomedical Engineering, Boston University Boston MA 02215 USA plally@bu.edu canvasback@gmail.com catherin@bu.edu.

James E Galagan (JE)

Department of Microbiology, Boston University Boston MA 02118 USA rcbaer@gmail.com jgalag@bu.edu.
Department of Biomedical Engineering, Boston University Boston MA 02215 USA plally@bu.edu canvasback@gmail.com catherin@bu.edu.
National Emerging Infectious Diseases Laboratories, Boston University Boston MA 02118 USA.

Mark W Grinstaff (MW)

Department of Chemistry, Boston University Boston MA 02215 USA chloe.grazon@u-bordeaux.fr mgrin@bu.edu.
Division of Materials Science and Engineering, Boston University Boston MA 02215 USA margaret.chern@gmail.com aldennis@bu.edu.
Department of Biomedical Engineering, Boston University Boston MA 02215 USA plally@bu.edu canvasback@gmail.com catherin@bu.edu.

Classifications MeSH