Heme oxygenase-1 gene rs2071746 polymorphism in retinal vein occlusion.
HMOX1
HO-1
Heme oxygenase-1
RVO
polymorphism
retinal vein occlusion
Journal
Ophthalmic genetics
ISSN: 1744-5094
Titre abrégé: Ophthalmic Genet
Pays: England
ID NLM: 9436057
Informations de publication
Date de publication:
10 2022
10 2022
Historique:
pubmed:
29
6
2022
medline:
28
9
2022
entrez:
28
6
2022
Statut:
ppublish
Résumé
Heme oxygenase-1 (HO-1) is an important cytoprotective enzyme due to its ability to degrade pro-inflammatory heme. The common single nucleotide polymorphism (SNP) rs2071746 on the We included 496 RVO patients and 297 control subjects in this case-control study. Genotypes of the rs2071746 polymorphism were determined by TaqMan assays. There was no association between the rs2071746 genotype and the presence of RVO ( The rs2071746 polymorphism does not seem to be a major risk factor for the presence of RVO.
Sections du résumé
BACKGROUND
Heme oxygenase-1 (HO-1) is an important cytoprotective enzyme due to its ability to degrade pro-inflammatory heme. The common single nucleotide polymorphism (SNP) rs2071746 on the
METHODS
We included 496 RVO patients and 297 control subjects in this case-control study. Genotypes of the rs2071746 polymorphism were determined by TaqMan assays.
RESULTS
There was no association between the rs2071746 genotype and the presence of RVO (
CONCLUSION
The rs2071746 polymorphism does not seem to be a major risk factor for the presence of RVO.
Identifiants
pubmed: 35762119
doi: 10.1080/13816810.2022.2092754
doi:
Substances chimiques
Heme
42VZT0U6YR
Heme Oxygenase-1
EC 1.14.14.18
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM