Nomogram predicting the probability of spontaneous stone passage in patients presenting with acute ureteric colic.
Ureteric colic
multivariable
normogram
predict
spontaneous stone passage
Journal
BJU international
ISSN: 1464-410X
Titre abrégé: BJU Int
Pays: England
ID NLM: 100886721
Informations de publication
Date de publication:
28 Jun 2022
28 Jun 2022
Historique:
entrez:
28
6
2022
pubmed:
29
6
2022
medline:
29
6
2022
Statut:
aheadofprint
Résumé
To develop a nomogram that could predict spontaneous stone passage (SSP) in patients presenting with acute ureteric colic who are suitable for conservative management. A 2517 patient dataset was utilised from an international multi-centre cohort study (MIMIC, A Multi-centre Cohort Study Evaluating the role of Inflammatory Markers In Patients Presenting with Acute Ureteric Colic) of patients presenting with acute ureteric colic across 71 secondary care hospitals in the United Kingdom, Ireland, Australia, and New Zealand. Inclusion criteria mandated a non-contrast CT-KUB. SSP was defined as the 'absence of the need for intervention'. The model was developed using logistic regression and backwards selection (to achieve lowest AIC) in a subset from 2009-2015 (n=1728) and temporally validated on a subset from 2016-2017 (n=789). Of the 2517 patients, 1874 had SSP (74.5%). Mean age (±[SD]) was 47 (±14.7) years and 1892 were male (75.2%). At the end of the modelling process, gender: male (OR 0.8, 95%CI 0.64-1.01, p=0.07), neutrophil count (OR 1.03, 95%CI 1.00-1.06, p = 0.08), hydronephrosis (OR 0.79, 95%CI 0.59-1.05, p=0.1), hydroureter (OR 1.3, 95%CI 0.97-1.75, p =0.08), stone size >5-7mm (OR 0.2, 95%CI 0.16-0.25, p<0.0001), stone size >7mm (OR 0.11, 95%CI 0.08-0.15, p<0.001), middle ureter stone position (OR 0.59, 95%CI 0.43-0.81, p=0.001), upper ureter stone position (OR 0.31, 95%CI 0.25-0.39, p<0.001) ), medical expulsive therapy use (OR 1.36, 95%CI 1.1 - 1.67, p = 0.001), oral NSAID use (OR 1.3, 95%CI 0.99 - 1.71, p=0.06), and rectal NSAID use (OR1.17, 95%CI 0.9 - 1.53, p=0.24) remained. Concordance-statistic (C-statistic) was 0.77 (95%CI 0.75 - 0.80) and a nomogram was developed based on these. The presented nomogram is available to use as an online calculator via www.BURSTurology.com and could allow clinicians and patients to make a more informed decision on pursuing conservative management versus early intervention.
Identifiants
pubmed: 35762278
doi: 10.1111/bju.15839
pmc: PMC9796920
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Investigateurs
H Abboudi
(H)
H Abdelmoteleb
(H)
M Abu Yousif
(M)
P Acher
(P)
R Adams
(R)
M Ager
(M)
I Ahmed
(I)
L Ajayi
(L)
A Akintimehin
(A)
J Akman
(J)
S Al Hayek
(S)
W Al-Dhahir
(W)
Z Al-Qassim
(Z)
S Al-Shakhshir
(S)
M Alberto
(M)
C Ali Abdaal
(C)
M Arya
(M)
N Assaf
(N)
B Ayres
(B)
H Badgery
(H)
K Bateman
(K)
A Bdesha
(A)
N Bedi
(N)
R Begum
(R)
M Belal
(M)
C S Biyani
(CS)
D Bolton
(D)
M Bultitude
(M)
F Burge
(F)
J Bycroft
(J)
F Cameron
(F)
A Campbell
(A)
A Cannon
(A)
A Carrie
(A)
B Chappell
(B)
Aol Chin
(A)
K Chow
(K)
D Christidis
(D)
J Clements
(J)
J Coode-Bate
(J)
P Cronbach
(P)
D Curry
(D)
R Dasgupta
(R)
S Demirel
(S)
L Derbyshire
(L)
W Din
(W)
E Docherty
(E)
E Edison
(E)
D Eldred-Evans
(D)
G Ellis
(G)
S Evans
(S)
R Foley
(R)
R Frymann
(R)
M Gallagher
(M)
B Gowardhan
(B)
J Graham
(J)
S Graham
(S)
S Gray
(S)
P Grice
(P)
S Gupta
(S)
S Hamad
(S)
G Hann
(G)
A Harris
(A)
E Hatem
(E)
A Hawary
(A)
Z Hayat
(Z)
D Hayne
(D)
M Hegazy
(M)
J Henderson
(J)
J Hendry
(J)
C Ho
(C)
A Hughes-Hallet
(A)
A Hussain
(A)
Z Hussain
(Z)
H Ibrahim
(H)
S Irving
(S)
N Ivin
(N)
A Jaffer
(A)
R Jalil
(R)
F Kashora
(F)
R Kavia
(R)
L Kerr
(L)
S Khadouri
(S)
A Khan
(A)
M Khan
(M)
S Khan
(S)
S Koschel
(S)
A A Kozan
(AA)
F Kum
(F)
H Kynaston
(H)
A Laird
(A)
L Lavan
(L)
N Lawrentschuk
(N)
Jcm Lee
(J)
S Lee
(S)
M Liew
(M)
K Mackenzie
(K)
M Malki
(M)
D Manson-Bahr
(D)
H Mason
(H)
M Matanhelia
(M)
J Maw
(J)
J Mbuvi
(J)
N Mc Cauley
(N)
S Mc Grath
(S)
A C Mc Kay
(AC)
C Mcilhenny
(C)
I Miakhil
(I)
M Miller
(M)
A B Mirza
(AB)
V Morrison-Jones
(V)
J Morrow
(J)
R Mosey
(R)
K Murtagh
(K)
M Natarajan
(M)
Y Nehikhare
(Y)
D Ness
(D)
A Ng
(A)
S Ngweso
(S)
N Nkwam
(N)
M Nyandoro
(M)
T Nzenza
(T)
J O' Brien
(J)
J O' Rourke
(J)
J O' Brien
(J)
P Olaniyi
(P)
J Olivier
(J)
B Osman
(B)
A Oyekan
(A)
K Pang
(K)
R Pankhania
(R)
I Parwaiz
(I)
B Parys
(B)
J Patterson
(J)
I Pearce
(I)
S Phipps
(S)
Y Premakumar
(Y)
J L Probert
(JL)
D Quinlan
(D)
H Ratan
(H)
K Reid
(K)
M Rezacova
(M)
S Rezvani
(S)
F Rodger
(F)
A Rogers
(A)
D Ross
(D)
C Rowbotham
(C)
P Rujancich
(P)
P Ruljancich
(P)
I Sadien
(I)
A Sakthivel
(A)
A Saleemi
(A)
A Samsudin
(A)
S Sandhu
(S)
L Seaward
(L)
A Sharma
(A)
S Sharma
(S)
I Shergill
(I)
A Shetty
(A)
C Shingles
(C)
L Simmons
(L)
R Simpson
(R)
N Simson
(N)
H Singh
(H)
D Smith
(D)
S Sriprasad
(S)
R Stammeijer
(R)
C Steen
(C)
H Stewart
(H)
T Stonier
(T)
L Suraparaj
(L)
D Swallow
(D)
A Symes
(A)
R Symes
(R)
K Tailor
(K)
C Tait
(C)
J P Tam
(JP)
J Tay
(J)
L J Tay
(LJ)
R Tregunna
(R)
E Tudor
(E)
C Udovichich
(C)
N Umez-Eronini
(N)
L Wang
(L)
A Ward
(A)
G Weeratunga
(G)
J Withington
(J)
C Wong
(C)
S Wozniak
(S)
O Yassaie
(O)
M Young
(M)
Informations de copyright
This article is protected by copyright. All rights reserved.
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