"Lockdown-thrombosis"-an unexpected problem of the COVID-19 pandemic?
COVID-19
Lockdown
Prolonged sitting
Seated immobility syndrome
Venous thromboembolism
Journal
Journal of thrombosis and thrombolysis
ISSN: 1573-742X
Titre abrégé: J Thromb Thrombolysis
Pays: Netherlands
ID NLM: 9502018
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
accepted:
21
03
2022
pubmed:
29
6
2022
medline:
9
7
2022
entrez:
28
6
2022
Statut:
ppublish
Résumé
Seated immobility thromboembolism syndrome (SIT) is the association of prolonged seated immobility with increased risk of venous thromboembolism (VTE). The advent of COVID-19 resulted in implementation of lockdowns to curb its spread. This resulted in compulsory work from home and minimization of outdoor activities. Consequently, this would have likely led to increased prolonged sitting and reduced mobility. Few case reports and studies have observed an increase in VTE incidence during the lockdown period. We likewise performed a clinical audit of our weekly thrombosis clinic cases and revealed three cases of VTE associated with prolonged sitting during Singapore's COVID-19 lockdown. Notably, all had other minor VTE risk factors in addition to prolonged sitting. All cases had intermediate-high risk pulmonary embolism and were given extended anticoagulation. With the pandemic still ongoing, periodic lockdown and quarantine measures may continue to be imposed. While the overall VTE risk conferred by prolonged seated immobility associated with lockdown measures is likely to be small, this risk can be easily mitigated and possibly prevented by simply staying mobile.
Identifiants
pubmed: 35763167
doi: 10.1007/s11239-022-02648-y
pii: 10.1007/s11239-022-02648-y
pmc: PMC9244410
doi:
Types de publication
Letter
Langues
eng
Sous-ensembles de citation
IM
Pagination
29-32Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Références
Beasley R, Heuser P, Raymond N (2005) SIT (seated immobility thromboembolism) syndrome: a 21st century lifestyle hazard. N Z Med J Apr 1(1212):U1376
Healy B, Levin E, Perrin K, Weatherall M, Beasley R (2010) Prolonged work- and computer-related seated immobility and risk of venous thromboembolism. J R Soc Med 103(11):447–454. doi: https://doi.org/10.1258/jrsm.2010.100155
doi: 10.1258/jrsm.2010.100155
pubmed: 21037335
pmcid: 2966881
Aldington S, Pritchard A, Perrin K, James K, Wijesinghe M, Beasley R (2008) Prolonged seated immobility at work is a common risk factor for venous thromboembolism leading to hospital admission. Intern Med J Feb 38(2):133–135. doi: https://doi.org/10.1111/j.1445-5994.2007.01597.x
doi: 10.1111/j.1445-5994.2007.01597.x
Braithwaite I, Healy B, Cameron L, Weatherall M, Beasley R (2016) Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: A case-control study. JRSM open 7(8):2054270416632670–2054270416632670. doi: https://doi.org/10.1177/2054270416632670
doi: 10.1177/2054270416632670
pubmed: 27540486
pmcid: 4973402
West J, Perrin K, Aldington S, Weatherall M, Beasley R (May 2008) A case-control study of seated immobility at work as a risk factor for venous thromboembolism. J R Soc Med 101(5):237–243. doi: https://doi.org/10.1258/jrsm.2008.070366
Johannesen CDL, Flachs EM, Ebbehøj NE et al (2020) Sedentary work and risk of venous thromboembolism. Scand J Work Environ Health Jan 1(1):69–76. doi: https://doi.org/10.5271/sjweh.3841
doi: 10.5271/sjweh.3841
Clark SL, Onida S, Davies A (Jun 2018) Long-haul travel and venous thrombosis: What is the evidence? Phlebology. 33:295–297. https://doi.org/10.1177/0268355517717423 . 5
Cheng J, Chowdhury SR, Dutta A, Ponampalam R (2020) Venous thromboembolism in a healthy young man: An unintended consequence of coronavirus disease 2019 pandemic lockdown. World J Emerg Med 11(4):255–257. doi: https://doi.org/10.5847/wjem.j.1920-8642.2020.04.008
doi: 10.5847/wjem.j.1920-8642.2020.04.008
pubmed: 33014222
pmcid: 7517402
Vannini L, Llanos Gómez JM, Quijada-Fumero A, Fernández Pérez AB, Hernández Afonso JS (2020) COVID-19 quarantine and acute pulmonary embolism. Rev Esp Cardiol (Engl Ed) Aug 73(8):680–682. doi: https://doi.org/10.1016/j.rec.2020.05.010
doi: 10.1016/j.rec.2020.05.010
Karaali E, Çiloğlu O, Demirtürk OS, Keklikçioğlu B, Akçay İ, Ekiz T (2021) Increased deep vein thrombosis cases during the COVID-19 quarantine. Phlebology Mar 36(2):114–118. doi: https://doi.org/10.1177/0268355520977294
doi: 10.1177/0268355520977294
Konstantinides SV, Meyer G, Becattini C et al (2020) 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J Jan 21(4):543–603. doi: https://doi.org/10.1093/eurheartj/ehz405
doi: 10.1093/eurheartj/ehz405
Speletas M (2021) Awareness of thrombotic disease during lockdown: an unusual consequence of the COVID-19 pandemic. J Thromb Thrombolysis Aug 52(2):466–467. doi: https://doi.org/10.1007/s11239-020-02355-6
doi: 10.1007/s11239-020-02355-6
Ali A, Omore I, Asare L, Gabani M, Riaz M, SEATED-IMMOBILITY THROMBOEMBOLISM SYNDROME COMPLICATING CORONAVIRUS (2020) DISEASE 2019 OUTBREAK QUARANTINE. Chest 158(4):A1614–A1614. doi: https://doi.org/10.1016/j.chest.2020.08.1453
doi: 10.1016/j.chest.2020.08.1453
Franch-Llasat D, Mayor-Vázquez E, Pedregosa-Díaz J, Herrero-Redondo M, Ortin-Font X, Roche-Campo F (Mar 2021) e-Thrombosis in the COVID-19 era: collateral effects of confinement. Med Intensiva (Engl Ed) 45(2):122–124 e-Thrombosis en época COVID-19. doi: https://doi.org/10.1016/j.medin.2020.08.003 . Efectos colaterales del confinamiento