Feeding tube use is associated with severe scoliosis in patients with cerebral palsy and limited ambulatory ability.


Journal

Spine deformity
ISSN: 2212-1358
Titre abrégé: Spine Deform
Pays: England
ID NLM: 101603979

Informations de publication

Date de publication:
11 2022
Historique:
received: 27 07 2021
accepted: 05 06 2022
pubmed: 29 6 2022
medline: 21 10 2022
entrez: 28 6 2022
Statut: ppublish

Résumé

Cerebral palsy (CP) is the most common motor disorder in childhood. Scoliosis is a common complication of CP that can reach clinically severe levels, but predictors for scoliosis in CP are not well understood. Some variables identified in the literature involve the severity of the brain injury and the presence of hip deformity. We aimed to identify associations with developing severe scoliosis in a prospective cohort of patients with cerebral palsy at higher risk for severe curve progression. This study reviewed a prospectively collected database at a tertiary children's hospital. We evaluated a panel of potential associations with severe scoliosis-including age, sex, Gross Motor Function Classification System (GMFCS) class, history of hip surgery, epilepsy, and feeding tube presence-in a population of children with limited ambulatory ability defined as GMFCS level IV or V CP. Univariate analysis and multivariate logistic regression with stepwise selection was used for analysis. Descriptive analysis showed that female sex, higher GMFCS class, history of hip surgery, non-upright seating, pelvic obliquity, presence of epilepsy, and presence of a feeding tube were associated with an increased risk for scoliosis. Multivariate logistic regression analysis revealed that the presence of a feeding tube was associated with severe scoliosis even when controlling for GMFCS and age. Feeding tube use may stratify risk for severe scoliosis progression in patients with GMFCS IV or V CP.

Identifiants

pubmed: 35764871
doi: 10.1007/s43390-022-00540-6
pii: 10.1007/s43390-022-00540-6
pmc: PMC9579063
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1415-1421

Subventions

Organisme : NIH HHS
ID : UL1TR002733
Pays : United States

Informations de copyright

© 2022. The Author(s).

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Auteurs

Nicholas Yoo (N)

College of Medicine, The Ohio State University, Columbus, OH, USA.

Brian Arand (B)

Nationwide Children's Hospital, Columbus, OH, USA.

Junxin Shi (J)

Nationwide Children's Hospital, Columbus, OH, USA.

Jingzhen Yang (J)

Nationwide Children's Hospital, Columbus, OH, USA.

Garey Noritz (G)

Nationwide Children's Hospital, Columbus, OH, USA.

Amanda T Whitaker (AT)

Nationwide Children's Hospital, Columbus, OH, USA. Amanda.Whitaker@shrinenet.org.
Shriners Hospital Northern California, University of California Davis, Sacramento, CA, USA. Amanda.Whitaker@shrinenet.org.

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