Psychological distress, understanding of cancer and illness uncertainty in patients with Cancer of Unknown Primary.
cancer
illness uncertainty
oncology
psycho-oncology
psychological distress
understanding of cancer
unknown primary tumour site
Journal
Psycho-oncology
ISSN: 1099-1611
Titre abrégé: Psychooncology
Pays: England
ID NLM: 9214524
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
revised:
24
05
2022
received:
14
02
2022
accepted:
22
06
2022
pubmed:
30
6
2022
medline:
10
11
2022
entrez:
29
6
2022
Statut:
ppublish
Résumé
Patients diagnosed with Cancer of Unknown Primary (CUP) experience high levels of psychological distress and report poor understanding of their cancer. We aimed to investigate: (1) if CUP patients with poorer understanding of their cancer diagnosis and testing experience more symptoms of psychological distress than those with better understanding; (2) if the relationship between patients' understanding of their cancer and psychological distress is mediated by illness uncertainty; and (3) explore whether patients' degree of understanding of their cancer can be predicted by clinical and socio-demographic factors. 209 CUP patients completed a questionnaire measuring anxiety, depression, illness uncertainty, fatigue, pain, sleep and understanding of their cancer. Using an apriori theoretical framework, we employed structural equation modelling to investigate predictors of patient's understanding of their cancer and psychological distress and the relationships between understanding, illness uncertainty and distress. The structural equation model displayed good fit indices and supported the hypothesised relationship of patient's understanding of their cancer and the extent of psychological distress, which was mediated via illness uncertainty. Physical symptoms were positively associated with psychological distress and illness uncertainty. Younger age was predictive of lower patient's understanding of their cancer and higher levels of psychological distress. Patients with CUP, particularly those who are younger and experiencing more physical symptoms, report higher levels of psychological distress and may require additional mental health support. Our findings highlight a need to improve CUP patient's understanding about their illness, which could help reduce their illness uncertainty and alleviate psychological distress.
Identifiants
pubmed: 35765251
doi: 10.1002/pon.5990
pmc: PMC9796856
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1869-1876Informations de copyright
© 2022 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd.
Références
J Gen Intern Med. 2008 Aug;23(8):1273-6
pubmed: 18452047
Psychooncology. 2022 Nov;31(11):1869-1876
pubmed: 35765251
J Pediatr Psychol. 2016 Apr;41(3):309-18
pubmed: 26423322
Lancet. 2012 Apr 14;379(9824):1428-35
pubmed: 22414598
Psychosomatics. 2009 Sep-Oct;50(5):440-7
pubmed: 19855028
J Natl Cancer Inst. 1993 Mar 3;85(5):365-76
pubmed: 8433390
Pathology. 2015 Jan;47(1):7-12
pubmed: 25485653
Asia Pac J Clin Oncol. 2012 Mar;8(1):14-23
pubmed: 22369440
Appl Nurs Res. 2011 Nov;24(4):193-9
pubmed: 20974073
Ann Oncol. 2011 Apr;22(4):761-772
pubmed: 20870912
Support Care Cancer. 2016 Jan;24(1):409-418
pubmed: 26093976
Psychooncology. 2010 Sep;19(9):901-8
pubmed: 20799373
J Health Psychol. 2016 Jun;21(6):1145-56
pubmed: 25205777
Cancer Nurs. 2008 Jul-Aug;31(4):274-83
pubmed: 18600114
Res Nurs Health. 2006 Feb;29(1):18-39
pubmed: 16404732
Med Care. 2007 May;45(5 Suppl 1):S22-31
pubmed: 17443115
Psychooncology. 2013 Sep;22(9):2009-15
pubmed: 23359412
Intern Med J. 2017 Apr;47(4):408-414
pubmed: 28101916
Psychooncology. 2000 Jan-Feb;9(1):11-9
pubmed: 10668055
Psychol Med. 2014 Jul;44(10):2029-40
pubmed: 24168753
Support Care Cancer. 2018 May;26(5):1655-1664
pubmed: 29222598
Curr Psychiatry Rep. 2009 Aug;11(4):269-76
pubmed: 19635234
Eur J Cancer Care (Engl). 2021 Nov;30(6):e13508
pubmed: 34755410
Eur J Cancer. 2011 Nov;47(17):2493-511
pubmed: 22033323
Cancer Nurs. 2006 Sep-Oct;29(5):400-5
pubmed: 17006114
J Nurs Scholarsh. 2008;40(1):60-7
pubmed: 18302593
Br Med Bull. 2009;92:135-52
pubmed: 19776035
Palliat Med. 2008 Mar;22(2):177-83
pubmed: 18372382
Aust Fam Physician. 2015 Sep;44(9):640-3
pubmed: 26488041
J Psychosoc Oncol. 2005;23(2-3):101-14
pubmed: 16492654
Ann Oncol. 2003 Jan;14(1):48-56
pubmed: 12488292
BMJ Open. 2017 Sep 27;7(9):e017881
pubmed: 28963312
BMJ Support Palliat Care. 2015 Dec;5(4):366-72
pubmed: 24644189