The Effect of Monitoring System on Risk Assessment of Aflatoxins in Iran's Pistachio Nuts Exported to the E.U. During 2012 - 2018.
Aflatoxins
Dietary Exposure
HPLC
Pistachio
Risk Assessment
Journal
Iranian journal of pharmaceutical research : IJPR
ISSN: 1726-6890
Titre abrégé: Iran J Pharm Res
Pays: Netherlands
ID NLM: 101208407
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
22
08
2021
revised:
13
12
2021
accepted:
25
12
2021
entrez:
29
6
2022
pubmed:
30
6
2022
medline:
30
6
2022
Statut:
epublish
Résumé
Pistachio has high nutritional value and popularity. The susceptibility of pistachio to aflatoxin contamination caused establishing a monitoring system introduced and implemented by the Ministry of Health in Iran to ensure consumers' access to safe and hygienic pistachios. In this research, aflatoxin contamination level in all consignments (7298) exporting to E.U. was examined using HPLC with fluorescence detection after immunoaffinity column clean up from Nov 2012 to Oct 2018. The average recoveries ranged 78.6% - 97.6%, with a relative standard deviation for reproducibility below 8.5% and expanded uncertainty of aflatoxin B1 (AFB1) at spiked levels 1, 4, and 8 ng/g were 0.17, 0.57, 0.89 ng/g, respectively. The results showed that aflatoxin B1 and total (AFT) were detected in 1921 (23.4%) and 1927 cases (23.5%), with the mean values ranging from 2.18 - 4.6 ng/g and 2.8 - 5.1 ng/g during six consecutive years, respectively. Implementing an effective monitoring system for pistachio nuts could determine consignments contaminated with aflatoxins. Concerning AFB1, risk assessments recorded for dietary exposure dose, margin of exposure (MOE), Hazard Index (HI), estimated liver cancer risk, and cancer incidence attributable to dietary ranged 0.0132 - 0.1180 ng/kg.bw/day, 1441 - 12843, 0.21 - 1.84, 0.00071 - 0.00633 cases/10
Identifiants
pubmed: 35765509
doi: 10.5812/ijpr.123951
pmc: PMC9191219
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e123951Informations de copyright
Copyright © 2022, Author(s).
Déclaration de conflit d'intérêts
Conflict of Interests: The authors declare that they have no conflict of interest.
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