Enteric viruses replicate in salivary glands and infect through saliva.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
07 2022
Historique:
received: 22 09 2020
accepted: 23 05 2022
pubmed: 30 6 2022
medline: 16 7 2022
entrez: 29 6 2022
Statut: ppublish

Résumé

Enteric viruses like norovirus, rotavirus and astrovirus have long been accepted as spreading in the population through fecal-oral transmission: viruses are shed into feces from one host and enter the oral cavity of another, bypassing salivary glands (SGs) and reaching the intestines to replicate, be shed in feces and repeat the transmission cycle

Identifiants

pubmed: 35768512
doi: 10.1038/s41586-022-04895-8
pii: 10.1038/s41586-022-04895-8
pmc: PMC9243862
doi:

Substances chimiques

Immunoglobulin A 0

Types de publication

Journal Article Research Support, N.I.H., Intramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

345-350

Subventions

Organisme : NIAID NIH HHS
ID : R21 AI166821
Pays : United States
Organisme : Intramural NIH HHS
ID : ZIA DE000695
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2022. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.

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Auteurs

S Ghosh (S)

Laboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

M Kumar (M)

Laboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

M Santiana (M)

Laboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

A Mishra (A)

Laboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

M Zhang (M)

Laboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

H Labayo (H)

Laboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

A M Chibly (AM)

Matrix and Morphogenesis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

H Nakamura (H)

AAV Biology Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

T Tanaka (T)

AAV Biology Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

W Henderson (W)

Faculty of Nursing, University of Connecticut, Storrs, CT, USA.

E Lewis (E)

Metaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Microbiome Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

O Voss (O)

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.

Y Su (Y)

Advanced Imaging and Microscopy Resource, National Institutes of Health, Bethesda, MD, USA.
Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.

Y Belkaid (Y)

Metaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Microbiome Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

J A Chiorini (JA)

AAV Biology Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

M P Hoffman (MP)

Matrix and Morphogenesis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

N Altan-Bonnet (N)

Laboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA. nihal.altan-bonnet@nih.gov.

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