Successful weaning of a patient with severe COVID-19 pneumonia under prolonged midazolam sedation using morphine.


Journal

Oxford medical case reports
ISSN: 2053-8855
Titre abrégé: Oxf Med Case Reports
Pays: England
ID NLM: 101642070

Informations de publication

Date de publication:
Jun 2022
Historique:
received: 18 08 2021
revised: 30 03 2022
accepted: 12 04 2022
entrez: 30 6 2022
pubmed: 1 7 2022
medline: 1 7 2022
Statut: epublish

Résumé

The coronavirus disease 2019 (COVID-19) pandemic continues to spread around the world. In April 2021, Japan experienced a fourth wave of COVID-19 infections, which led to the breakdown of the medical system. Osaka, Japan, was particularly affected, with many severe cases and the highest number of COVID-19-associated deaths in Japan. Herein, we present a patient with severe COVID-19 infection who received prolonged midazolam (MDZ) treatment since propofol was not available due to shortage of medical resources. Moreover, the duration of mechanical ventilation was extended due to the development of a pneumothorax. When MDZ tapering was initiated, tachypnea was observed, which resulted failure in ventilator weaning. However, the use of continuous morphine infusion led a successful weaning off the ventilator. We suggest that the administration of morphine may allow for a smoother weaning process for some patients with severe COVID-19 infection.

Identifiants

pubmed: 35769183
doi: 10.1093/omcr/omac051
pii: omac051
pmc: PMC9235016
doi:

Types de publication

Case Reports

Langues

eng

Pagination

omac051

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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Auteurs

Kei Kunimasa (K)

Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.

Yoshifumi Ohashi (Y)

Department of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.

Megumi Okawa (M)

Department of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.

Hiroshi Iida (H)

Department of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.

Shunji Sonoda (S)

Department of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.

Yuki Hiuge (Y)

Department of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.

Masaaki Hachimine (M)

Department of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.

Ai Yamamura (A)

Department of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.

Takahisa Kawamura (T)

Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.

Takako Inoue (T)

Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.

Motohiro Tamiya (M)

Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.

Hanako Kuhara (H)

Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.

Kazumi Nishino (K)

Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.

Naoki Nakamoto (N)

Department of Emergency and Critical Care, Osaka General Medical Center, Osaka, Japan.

Toru Kumagai (T)

Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.

Hironobu Tanigami (H)

Department of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.

Classifications MeSH