Lactic Acid Bacterial Supplementation Ameliorated the Lipopolysaccharide-Induced Gut Inflammation and Dysbiosis in Mice.
Lactobacillus
inflammation
intestinal permeability
lipopolysaccharide
tight junction proteins
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2022
2022
Historique:
received:
28
04
2022
accepted:
16
05
2022
entrez:
30
6
2022
pubmed:
1
7
2022
medline:
1
7
2022
Statut:
epublish
Résumé
Lipopolysaccharide (LPS), a gut-transmitted endotoxin from Gram-negative bacteria, causes inflammatory diseases leading to the loss of gut barrier integrity and has been identified as a major pathogenic stimulator in many dysfunctions. Hence, supplementation with probiotics is believed to be one of the most effective strategies for treating many inflammatory gut disorders. Although probiotics are known to have a variety of therapeutic characteristics and to play a beneficial role in host defense responses, the molecular mechanisms by which they achieve these beneficial effects are unknown due to species- and strain-specific behaviors. Therefore, in this study, the protective role of five indigenous lactic acid bacterial strains in ameliorating LPS-induced gut barrier impairment in the C57BL/6 mice model was elucidated.
Identifiants
pubmed: 35770157
doi: 10.3389/fmicb.2022.930928
pmc: PMC9235405
doi:
Types de publication
Journal Article
Langues
eng
Pagination
930928Informations de copyright
Copyright © 2022 Bhatia, Sharma, Bhadada, Bishnoi and Kondepudi.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Exp Physiol. 2017 Jul 1;102(7):791-803
pubmed: 28436589
Sci Rep. 2016 Jun 21;6:28332
pubmed: 27323686
Microb Cell Fact. 2017 May 8;16(1):79
pubmed: 28482838
Oncogene. 2016 May 19;35(20):2645-54
pubmed: 26364605
Eur J Nutr. 2015 Oct;54(7):1161-71
pubmed: 25408198
Front Microbiol. 2021 Sep 03;12:679773
pubmed: 34539597
PLoS One. 2018 Feb 14;13(2):e0192021
pubmed: 29444150
Food Sci Biotechnol. 2017 Nov 14;27(1):123-129
pubmed: 30263732
Arch Biochem Biophys. 1978 Feb;186(1):189-95
pubmed: 24422
Brain Behav Immun. 2016 Feb;52:120-131
pubmed: 26476141
Int J Obes (Lond). 2016 Mar;40(3):487-96
pubmed: 26395746
Front Immunol. 2021 Feb 26;12:578386
pubmed: 33717063
Microorganisms. 2022 Mar 30;10(4):
pubmed: 35456797
Sci Rep. 2021 Jan 12;11(1):571
pubmed: 33436961
Food Funct. 2018 Feb 21;9(2):1254-1264
pubmed: 29393319
Int J Mol Sci. 2020 Oct 05;21(19):
pubmed: 33027970
J Gastrointest Surg. 2022 Mar;26(3):671-683
pubmed: 34734369
Int J Immunopathol Pharmacol. 2014 Oct-Dec;27(4):615-27
pubmed: 25572742
Cell Metab. 2016 Aug 9;24(2):295-310
pubmed: 27508875
Regul Toxicol Pharmacol. 2019 Feb;101:1-11
pubmed: 30367905
Nucleic Acids Res. 2015 Jul 1;43(W1):W566-70
pubmed: 25969447
Eur J Nutr. 2020 Sep;59(6):2709-2728
pubmed: 31659451
Sci Rep. 2019 Apr 8;9(1):5790
pubmed: 30962497
Microorganisms. 2019 Aug 19;7(8):
pubmed: 31430948
Ann Nutr Metab. 2019;74(2):115-124
pubmed: 30673668
Biomed Pharmacother. 2018 Oct;106:1469-1477
pubmed: 30119221
J Surg Res. 2016 May 1;202(1):225-34
pubmed: 27083970
Front Immunol. 2017 Mar 13;8:266
pubmed: 28348560
Chronic Stress (Thousand Oaks). 2022 Feb 8;6:24705470221076390
pubmed: 35155966
Sci Rep. 2020 Feb 20;10(1):3107
pubmed: 32080230
Cell Rep. 2021 Sep 14;36(11):109691
pubmed: 34525353
Pharmacol Res. 2021 Oct;172:105795
pubmed: 34339837