Magnetic resonance imaging and histopathology of catheter ablation lesions after ventricular tachycardia ablation in patients with nonischemic cardiomyopathy.
Histopathology
Late gadolinium enhancement cardiac magnetic resonance
Nonischemic cardiomyopathy
Radiofrequency catheter ablation
Ventricular tachycardia
Journal
Heart rhythm
ISSN: 1556-3871
Titre abrégé: Heart Rhythm
Pays: United States
ID NLM: 101200317
Informations de publication
Date de publication:
10 2022
10 2022
Historique:
received:
24
04
2022
revised:
07
06
2022
accepted:
19
06
2022
pubmed:
1
7
2022
medline:
5
10
2022
entrez:
30
6
2022
Statut:
ppublish
Résumé
Late gadolinium enhanced cardiac magnetic resonance (LGE-CMR) imaging may help identify radiofrequency ablation lesions, which have been poorly described in patients with nonischemic cardiomyopathy (NICM). The purpose of this study was to describe LGE-CMR characteristics of ablation lesions in patients with NICM and correlate them with histopathology. Twenty-six patients (24 men; ejection fraction 38% ± 14%; age 61 ± 9 years) who had undergone CMR imaging after ventricular tachycardia (VT) ablation were included. Areas of both dark and bright core lesions correlating with previous radiofrequency ablation lesions were identified. Histology was performed on an explanted heart. Mean time between the ablation procedure and the LGE-CMR study was 8 [2-20] months. Twenty-three of 26 patients demonstrated dark core lesions (volume 2.16 ± 1.8 cm Ablation lesions can be detected by LGE-CMR after VT ablation in NICM patients and have a different appearance than scar tissue. These lesions can be observed in the acute and chronic settings after ablations.
Sections du résumé
BACKGROUND
Late gadolinium enhanced cardiac magnetic resonance (LGE-CMR) imaging may help identify radiofrequency ablation lesions, which have been poorly described in patients with nonischemic cardiomyopathy (NICM).
OBJECTIVES
The purpose of this study was to describe LGE-CMR characteristics of ablation lesions in patients with NICM and correlate them with histopathology.
METHODS
Twenty-six patients (24 men; ejection fraction 38% ± 14%; age 61 ± 9 years) who had undergone CMR imaging after ventricular tachycardia (VT) ablation were included. Areas of both dark and bright core lesions correlating with previous radiofrequency ablation lesions were identified. Histology was performed on an explanted heart.
RESULTS
Mean time between the ablation procedure and the LGE-CMR study was 8 [2-20] months. Twenty-three of 26 patients demonstrated dark core lesions (volume 2.16 ± 1.8 cm
CONCLUSION
Ablation lesions can be detected by LGE-CMR after VT ablation in NICM patients and have a different appearance than scar tissue. These lesions can be observed in the acute and chronic settings after ablations.
Identifiants
pubmed: 35772697
pii: S1547-5271(22)02156-7
doi: 10.1016/j.hrthm.2022.06.027
pii:
doi:
Substances chimiques
Contrast Media
0
Gadolinium
AU0V1LM3JT
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1642-1649Informations de copyright
Copyright © 2022. Published by Elsevier Inc.