Stressful life events and trajectories of depression symptoms in a U.S. military cohort.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
30 06 2022
Historique:
received: 04 11 2021
accepted: 08 06 2022
entrez: 30 6 2022
pubmed: 1 7 2022
medline: 6 7 2022
Statut: epublish

Résumé

Depression is a common mental disorder that may comprise distinct, underlying symptom patterns over time. Associations between stressful life events throughout the civilian lifecourse-including during childhood-and adult depression have been documented in many populations, but are less commonly assessed in military samples. We identified different trajectories of depression symptoms across four years in a military cohort using latent class growth analysis, and investigated the relationship between these trajectories and two domains of civilian life experiences: childhood adversity (e.g., being mistreated during childhood) and more proximal stressful experiences (e.g., divorce). A four-group depression model was identified, including a symptom-free group (62%), an increasing symptom group (13%), a decreasing symptom group (16%), and a "chronic" symptom group (9%). Compared to the symptom-free group, soldiers with childhood adversity were more likely to be in the chronic depression, decreasing, and increasing symptom groups. Time-varying adult stressors had the largest effect on depression symptoms for the increasing symptom group compared to other groups, particularly in the last two years of follow-up. This study indicates the importance of considering events from throughout the lifecourse-not only those from deployment-when studying the mental health of servicemembers.

Identifiants

pubmed: 35773360
doi: 10.1038/s41598-022-14496-0
pii: 10.1038/s41598-022-14496-0
pmc: PMC9246834
doi:

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

11026

Subventions

Organisme : NHLBI NIH HHS
ID : T32 HL098048
Pays : United States
Organisme : NIH HHS
ID : T32 HL098048
Pays : United States

Informations de copyright

© 2022. The Author(s).

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Auteurs

Laura Sampson (L)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA. Lasampson@hsph.harvard.edu.

Howard J Cabral (HJ)

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

Anthony J Rosellini (AJ)

Center for Anxiety and Related Disorders, Department of Psychological and Brain Science, Boston University, Boston, MA, USA.

Jaimie L Gradus (JL)

Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.

Gregory H Cohen (GH)

Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.

David S Fink (DS)

New York State Psychiatric Institute, New York, NY, USA.

Anthony P King (AP)

Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.

Israel Liberzon (I)

Department of Psychiatry, College of Medicine, Texas A&M University, College Station, TX, USA.

Sandro Galea (S)

Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Boston University School of Public Health, 715 Albany Street, Boston, MA, 02118, USA.

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