Azithromycin-Induced Liver Injury in an Asthma Exacerbation Patient With Autoimmune Features.

acute hepatitis asthma exacerbation autoimmune hepatitis azithromycin drug-induced liver injury

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
May 2022
Historique:
accepted: 29 05 2022
entrez: 1 7 2022
pubmed: 2 7 2022
medline: 2 7 2022
Statut: epublish

Résumé

Drug-induced liver injury (DILI) is one of the leading causes of acute liver failure in the United States. Antimicrobials are the most common class of drugs implicated in this pathology. Although azithromycin has been documented as a relatively safe drug, one of its rare and potentially fatal side effects is DILI. Diagnosing DILI is difficult because it is a diagnosis of exclusion. Autoimmune hepatitis (AIH) may present similarly to DILI, and a liver biopsy may be needed to differentiate between the two conditions. We present a case of azithromycin-induced liver injury in an asthma exacerbation patient with features of AIH.

Identifiants

pubmed: 35774698
doi: 10.7759/cureus.25447
pmc: PMC9239290
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e25447

Informations de copyright

Copyright © 2022, Liang et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

Arthritis Res Ther. 2011 Mar 02;13(2):R38
pubmed: 21366908
Eur J Med Chem. 2020 Dec 1;207:112739
pubmed: 32871342
Clin Exp Med. 2021 Sep 20;:
pubmed: 34542782
Cureus. 2021 Sep 9;13(9):e17856
pubmed: 34660061
Am J Health Syst Pharm. 2010 May 15;67(10):810-4
pubmed: 20479103
United European Gastroenterol J. 2019 Nov;7(9):1156-1163
pubmed: 31700628
Lancet. 2017 Aug 12;390(10095):659-668
pubmed: 28687413
J Hepatol. 2012 Feb;56(2):374-80
pubmed: 21889469
Front Neurol. 2021 Mar 09;12:652674
pubmed: 33767665
Am J Gastroenterol. 2014 Jul;109(7):950-66; quiz 967
pubmed: 24935270
Clin Liver Dis. 2013 Nov;17(4):575-86, viii
pubmed: 24099019
Pacing Clin Electrophysiol. 2005 Nov;28(11):1221-2
pubmed: 16359290
Clin Gastroenterol Hepatol. 2015 Feb;13(2):369-376.e3
pubmed: 25111234
Medicine (Baltimore). 2017 Dec;96(52):e9346
pubmed: 29384912
Am J Med. 2001 Mar;110(4):330-1
pubmed: 11247598
Gastroenterology. 2015 Jun;148(7):1340-52.e7
pubmed: 25754159
Liver Int. 2018 Jan;38(1):15-22
pubmed: 28432836
Hepatology. 2020 Aug;72(2):671-722
pubmed: 31863477
Pharm Res. 2019 Feb 7;36(3):48
pubmed: 30734107
J Hepatol. 1999 Nov;31(5):929-38
pubmed: 10580593

Auteurs

Richard Liang (R)

Medicine, New York Institute of Technology College of Osteopathic Medicine, Glen Head, USA.

Adesh Ramdass (A)

Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.

Classifications MeSH