Versatile Protein Coronation Approach with Multiple Depleted Serum for Creating Biocompatible, Precision Nanomedicine.
Au nanospheres
drug delivery
dysopsonin
protein corona
surface functionalization
Journal
Small (Weinheim an der Bergstrasse, Germany)
ISSN: 1613-6829
Titre abrégé: Small
Pays: Germany
ID NLM: 101235338
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
revised:
19
05
2022
received:
30
03
2022
pubmed:
2
7
2022
medline:
29
7
2022
entrez:
1
7
2022
Statut:
ppublish
Résumé
The protein corona effect has long been treated as the evil source behind delivery efficacy issues. In this study, this concept is challenged by showcasing that the protein corona can serve as a versatile functionalization approach to improve the delivery efficacy or mitigate nanocytotoxicity. To this end, the depleted serum is introduced to create nanomaterials carrying functionally distinct protein corona, referred to as PCylated nanomaterials. It is confirmed that the passivation with depleted serum helps reduce the toxicity and pro-inflammatory response. Furthermore, the same method can be leveraged to enhance the capacity of nanomaterials to undergo endocytosis as well as their potential as an agonist for the NF-κB pathways. The comparable stability of protein corona created by late and early-stage serum reveals that the chanceless interaction with nanomaterials, rather than an inadequate binding strength, may be behind the failure of enriching certain components. The PCylation strategy is extended to cancer patient-derived fluid, creating a set of T1 and T3-stage cancer-specific nanotherapeutics to retard the metastasis of cancer cells, while leaving normal endothelial negligibly affected. It is hoped the novel PCylation approach validated here can shed light on the future development of precision nanomedicine with improved delivery efficacy.
Identifiants
pubmed: 35775952
doi: 10.1002/smll.202202002
doi:
Substances chimiques
Protein Corona
0
Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2202002Informations de copyright
© 2022 Wiley-VCH GmbH.
Références
S. Wilhelm, A. J. Tavares, D. Qin, S. Ohta, W. C. Chan, Nat. Rev. Mater. 2016, 1, 16014.
T. Cedervall, I. Lynch, S. Lindman, T. Berggard, E. Thulin, H. Nilsson, K. A. Dawson, S. Linse, Proc. Natl. Acad. Sci. USA 2007, 104, 2050.
E. Casals, T. Pfaller, A. Duschl, G. J. Oostingh, V. Puntes, ACS Nano 2010, 4, 3623.
I. Lynch, A. Salvati, K. A. Dawson, Nat. Nanotechnol. 2009, 4, 546.
A. Salvati, A. S. Pitek, M. P. Monopoli, K. Prapainop, F. B. Bombelli, D. R. Hristov, P. M. Kelly, C. Åberg, E. Mahon, K. A. Dawson, Nat. Nanotechnol. 2013, 8, 137.
N. Bertrand, P. Grenier, M. Mahmoudi, E. M. Lima, E. A. Appel, F. Dormont, J. M. Lim, R. Karnik, R. Langer, O. C. Farokhzad, Nat. Commun. 2017, 8, 777.
B. D. Johnston, W. G. Kreyling, C. Pfeiffer, M. Schäffler, H. Sarioglu, S. Ristig, S. Hirn, N. Haberl, S. Thalhammer, S. M. Hauck, Adv. Funct. Mater. 2017, 27, 1701956.
S. Schöttler, G. Becker, S. Winzen, T. Steinbach, K. Mohr, K. Landfester, V. Mailänder, F. R. Wurm, Nat. Nanotechnol. 2016, 11, 372.
M. Wang, O. J. Gustafsson, G. Siddiqui, I. Javed, H. G. Kelly, T. Blin, H. Yin, S. J. Kent, D. J. Creek, K. Kempe, Nanoscale 2018, 10, 10863.
D. Rosenblum, N. Joshi, W. Tao, J. M. Karp, D. Peer, Nat. Commun. 2018, 9, 1410.
E. Papini, R. Tavano, F. Mancin, Front. Immunol. 2020, 11, 567365.
X. Lu, P. Xu, H. M. Ding, Y. S. Yu, D. Huo, Y. Q. Ma, Nat. Commun. 2019, 10, 4520.
I. Alberg, S. Kramer, M. Schinnerer, Q. Hu, R. Zentel, Small 2020, 16, 1907574.
G. Caracciolo, S. Palchetti, V. Colapicchioni, L. Digiacomo, D. Pozzi, A. L. Capriotti, G. La Barbera, A. Laganà, Langmuir 2015, 31, 10764.
F. Giulimondi, E. Vulpis, L. Digiacomo, M. V. Giuli, A. Mancusi, A. L. Capriotti, A. Laganà, A. Cerrato, R. Z. Chiozzi, C. Nicoletti, ACS Nano 2022, 16, 2088.
Y. Zheng, X. Zhong, Z. Li, Y. Xia, Part. Part. Syst. Charact. 2014, 31, 266.
D. Liu, W. Wu, J. Ling, S. Wen, N. Gu, X. Zhang, Adv. Funct. Mater. 2011, 21, 1498.
J. Lee, J. H. Huh, K. Kim, S. Lee, Adv. Funct. Mater. 2018, 28, 1707309.
A. Gessner, A. Lieske, B. R. Paulke, R. H. Müller, Eur. J. Pharm. Biopharm. 2002, 54, 165.
C. D. Walkey, J. B. Olsen, H. Guo, A. Emili, W. C. Chan, J. Am. Chem. Soc. 2012, 134, 2139.
L. Vroman, A. Adams, G. Fischer, P. Munoz, Blood 1980, 55, 156.
Z. Lyu, F. Zhou, Q. Liu, H. Xue, Q. Yu, H. Chen, Adv. Funct. Mater. 2016, 26, 5787.
X. Jiang, S. Weise, M. Hafner, C. Röcker, F. Zhang, W. J. Parak, G. U. Nienhaus, J. R. Soc. Interface 2010, 7, S5.
L. K. Müller, J. Simon, C. Rosenauer, V. Mailänder, S. Morsbach, K. Landfester, Biomacromolecules 2018, 19, 374.
V. H. Nguyen, B.-J. Lee, Int. J. Nanomed. 2017, 12, 3137.
C. Auffray, M. H. Sieweke, F. Geissmann, Annu. Rev. Immunol. 2009, 27, 669.
P. J. Murray, T. A. Wynn, Nat. Rev. Immunol. 2011, 11, 723.
M. A. Dobrovolskaia, S. E. Mcneil, Nat. Nanotechnol. 2007, 2, 469.
D. Zhang, L. Wei, M. Zhong, L. Xiao, H. W. Li, J. Wang, Chem. Sci. 2018, 9, 5260.
Z. Tu, K. Achazi, A. Schulz, R. Mülhaupt, S. Thierbach, E. Rühl, M. Adeli, R. Haag, Adv. Funct. Mater. 2017, 27, 1701837.
P. Khanna, C. Ong, B. H. Bay, G. H. Baeg, Nanomaterials 2015, 5, 1163.
P. J. Murray, J. E. Allen, S. K. Biswas, E. A. Fisher, D. W. Gilroy, S. Goerdt, S. Gordon, J. A. Hamilton, L. B. Ivashkiv, T. Lawrence, Immunity 2014, 41, 14.
S. Behzadi, V. Serpooshan, W. Tao, M. A. Hamaly, M. Y. Alkawareek, E. C. Dreaden, D. Brown, A. M. Alkilany, O. C. Farokhzad, M. Mahmoudi, Chem. Soc. Rev. 2017, 46, 4218.
C. H. Lai, C. Y. Lin, H. T. Wu, H. S. Chan, Y. J. Chuang, C. T. Chen, C. C. Lin, Adv. Funct. Mater. 2010, 20, 3948.
F. Charbgoo, M. Nejabat, K. Abnous, F. Soltani, S. M. Taghdisi, M. Alibolandi, W. T. Shier, T. W. Steele, M. J. Ramezani, J. Controlled Release 2018, 272, 39.
M. Almeida, E. Susnik, B. Drasler, P. Taladriz-Blanco, B. Rothen-Rutishauser, Chem. Soc. Rev. 2021, 50, 5397.
S. Sigismund, L. Lanzetti, G. Scita, P. P. Di Fiore, Nat. Rev. Mol. Cell Biol. 2021, 22, 625.
S. D. Tito, J. Hervás, A. Vliet, S. A. Tooze, Trends Biochem. Sci. 2020, 45, 484.
A. K. Varkouhi, M. Scholte, G. Storm, H. J. Haisma, J. Controlled Release 2011, 151, 220.
B. Rathore, K. Sunwoo, P. Jangili, J. Kim, J. H. Kim, M. Huang, J. Xiong, A. Sharma, Z. Yang, J. Qu, Biomaterials 2019, 211, 25.
I. Khan, P. S. Steeg, Brit. J. Cancer 2020, 124, 66.
M. Qin, J. Zhang, M. Li, D. Yang, D. Liu, S. Song, J. Fu, H. Zhang, W. Dai, X. Wang, Theranostics 2020, 10, 1213.
K. I. Cupic, J. J. Rennick, A. P. Johnston, G. K. Such, Nanomedicine 2019, 14, 215.
C. Almeida, M. D. Amaral, Cell. Mol. Life Sci. 2020, 77, 4729.
B. Kornmann, K. Weis, Science 2020, 367, 507.
G. Eelen, P. de Zeeuw, M. Simons, P. Carmeliet, Circ. Res. 2015, 116, 1231.
M. I. Setyawati, C. Y. Tay, D. Docter, R. H. Stauber, D. T. Leong, Chem. Soc. Rev. 2015, 44, 8174.
D. Du, N. Chang, S. Sun, M. Li, H. Yu, J. Controlled Release 2014, 182, 99.
G. Bazzoni, E. Dejana, Physiol. Rev. 2004, 84, 869.
P. Fang, R. Jinsong, Q. Xiaogang, Chem. Soc. Rev. 2018, 47, 404.
M. Munir, S. Hussain, R. Anwar, M. Waqas, J. Ali, Sci. Inquiry Rev. 2020, 4, 14.
L. F. Chen, W. C. Greene, Nat. Rev. Mol. Cell Biol. 2004, 5, 392.
P. Kinaret, G. Scala, A. Federico, J. Sund, D. Greco, Small 2020, 16, 1907609.
M. R. Zinatizadeh, B. Schock, G. M. Chalbatani, P. K. Zarandi, S. A. Jalali, S. R. Miri, Genes Dis. 2021, 8, 287.
S. Srijampa, S. Buddhisa, S. Ngernpimai, C. Leelayuwat, P. Tippayawat, Bioconjug. Chem. 2020, 31, 1133.
J. Ren, R. Cai, J. Wang, M. Daniyal, C. Chen, Nano Lett. 2019, 19, 4692.
A. Decout, J. D. Katz, S. Venkatraman, A. Ablasser, Nat. Rev. Immunol. 2021, 21, 548.
K. P. Hopfner, V. Hornung, Nat. Rev. Mol. Cell Biol. 2020, 21, 501.
B. Guey, A. Ablasser, Curr. Opin. Immunol. 2022, 74, 164.
Q. Zhou, Y. Zhou, T. Li, Z. Ge, Macromol. Biosci. 2021, 21, 2100133.
R. L. Siegel, K. D. Miller, A. G. Sauer, S. A. Fedewa, L. F. Butterly, J. C. Anderson, A. Cercek, R. A. Smith, A. Jemal, Ca-Cancer J. Clin. 2020, 70, 145.
X. Guan, H. H. Yin, X. H. Xu, G. Xu, Y. Zhang, B. G. Zhou, W. W. Yue, C. Liu, L. P. Sun, H. X. Xu, Adv. Funct. Mater. 2020, 30, 2000326.
R. V. Ghartavol, R. Mombeiny, A. Salmaninejad, S. M. R. Sorkhabadi, M. R. Jaafari, H. Mirzaei, J. Cell Physiol. 2018, 233, 9223.
C. C. Han, F. S. Wan, J. Breast Cancer 2018, 21, 354.
R. M. Visalakshan, L. E. González García, M. R. Benzigar, A. Ghazaryan, J. Simon, A. Mierczynska-Vasilev, T. D. Michl, A. Vinu, V. Mailänder, S. Morsbach, K. Landfester, K. Vasilev, Small 2020, 16, 2000285.
S. Abbina, L. E. Takeuchi, P. Anilkumar, K. Yu, J. C. Rogalski, R. A. Shenoi, I. Constantinescu, J. N. Kizhakkedathu, Nat. Commun. 2020, 11, 3048.
K. E. Wheeler, A. J. Chetwynd, K. M. Fahy, B. S. Hong, J. A. Tochihuitl, L. A. Foster, I. Lynch, Nat. Nanotechnol. 2021, 16, 617.
I. Alberg, S. Kramer, M. Schinnerer, Q. Hu, C. Seidl, C. Leps, N. Drude, D. Möckel, C. Rijcken, T. Lammers, M. Diken, M. Maskos, S. Morsbach, K. Landfester, S. Tenzer, M. Barz, R. Zentel, Small 2020, 16, 1907574.
E. Heideveld, M. Horcas-Lopez, M. Lopez-Yrigoyen, L. M. Forrester, J. W. Pollard, Method Enzymol. 2019, 632, 113.
H. Mohammad-Beigi, Y. Hayashi, C. M. Zeuthen, H. Eskandari, D. S. Sutherland, Nat. Commun. 2020, 11, 4535.