Non-oncologic incidental uptake on FAPI PET/CT imaging.

Humans Biological Transport Gallium Radioisotopes Kidney Liver Positron Emission Tomography Computed Tomography Positron-Emission Tomography

Journal

The British journal of radiology
ISSN: 1748-880X
Titre abrégé: Br J Radiol
Pays: England
ID NLM: 0373125

Informations de publication

Date de publication:
Feb 2023
Historique:
pmc-release: 01 02 2024
pubmed: 2 7 2022
medline: 27 1 2023
entrez: 1 7 2022
Statut: ppublish

Résumé

Fibroblast-activation protein (FAP) is a serine protease classified in the dipeptidyl peptidase 4 (DPP4) family. FAP is predominantly expressed in activated fibroblasts such as the cancer-associated fibroblasts (CAFs). FAP expression in CAFs is associated with tumor progression and poor prognosis in solid cancers. Recently, radiolabeled FAP inhibitors (FAPI) has been developed, which enables positron emission tomography (PET) imaging of FAP. FAPI PET/CT can provide a higher tumor-to-background ratio (TBR) than

Identifiants

DOI: 10.1259/bjr.20220463 PMID: 35776566 PMC: PMC9975522
pubmed: 35776566
doi: 10.1259/bjr.20220463
pmc: PMC9975522
doi:

Substances chimiques

Gallium Radioisotopes 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

20220463

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Auteurs

Masatoshi Hotta (M)

Ahmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology, University of California, Los Angeles, USA.
ORCID: 0000-0001-6790-8804

Angela C Rieger (AC)

Ahmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology, University of California, Los Angeles, USA.

Mahbod G Jafarvand (MG)

Ahmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology, University of California, Los Angeles, USA.

Nandakumar Menon (N)

Ahmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology, University of California, Los Angeles, USA.

Andrea Farolfi (A)

Ahmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology, University of California, Los Angeles, USA.

Matthias R Benz (MR)

Ahmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology, University of California, Los Angeles, USA.
Department of Radiological Sciences, University of California Los Angeles, Los Angeles, CA, United States.

Jeremie Calais (J)

Ahmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology, University of California, Los Angeles, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Non-oncologic incidental uptake on FAPI PET/CT imaging.
questionsmedicales.fr › Métabolisme › Transport biologique › Non-oncologic incidental uptake on FAPI PET/CT imaging.
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Gallium › Isotopes du gallium › Radio-isotopes du gallium › Non-oncologic incidental uptake on FAPI PET/CT imaging.
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Non-oncologic incidental uptake on FAPI PET/CT imaging.
questionsmedicales.fr › Système digestif › Foie › Non-oncologic incidental uptake on FAPI PET/CT imaging.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Tomographie par émission de positons couplée à la tomodensitométrie › Non-oncologic incidental uptake on FAPI PET/CT imaging.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Non-oncologic incidental uptake on FAPI PET/CT imaging.