An updated hip fracture incidence rate for Brazil: the Brazilian Validation Osteoporosis Study (BRAVOS).


Journal

Archives of osteoporosis
ISSN: 1862-3514
Titre abrégé: Arch Osteoporos
Pays: England
ID NLM: 101318988

Informations de publication

Date de publication:
02 07 2022
Historique:
received: 06 02 2022
accepted: 07 06 2022
entrez: 2 7 2022
pubmed: 3 7 2022
medline: 8 7 2022
Statut: epublish

Résumé

Hip fracture incidence rates in three representative geographic areas in Brazil over a period of 2 years (2010-2012) were assessed for the first time. Estimated incidence rates varied regionally, and markedly differed from those previously reported. Thus, national guidelines as well as FRAX Brazil should be revised in light of this new data. To determine the annual incidence of hip fractures in individuals aged 50 years and over, living in 3 cities located in different regions of the country. To investigate the age, gender, and regional differences in fracture rates. Based on the obtained data, to estimate the national incidence of hip fractures resulting from osteoporosis, in order to improve prevention strategies. Retrospective, observational study including all patients aged ≥ 50 years admitted in hospitals because of a hip fracture in three cities (Belem, Joinville, and Vitoria) from representative geographic areas in Brazil from 2010 to 2012. Data were obtained from medical records in those cities. We analyzed incidence rates (crude and age- and gender-standardized rates) for hip fractures. There were 1025 (310 in men and 715 in women) hip fractures in the over 50-year-old merged population from the three cities. The crude incidence rate for hip fracture was 103.3/100,000 (95% confidence interval [CI = 97.0; 109.7), in men 77.4/100,000 (95% CI = 68.8; 86.0), and in women 125.2/100,000 (95% CI = 116.0; 134.4). Incidence standardized for age and gender was 105.9 cases per 100,000 persons per year (95% CI = 99.4; 112.4); 78.5 cases per 100,000 (95% CI = 69.8; 87.3) in men and 130.6 cases 100,000 in women (95% CI = 121.0, 140.2) per year. Belem, located in the equatorial region (latitude 1° 27' S), had significantly lower crude and age-adjusted incidence than Joinville (latitude 26° 18' S) and Vitoria (latitude 20° 19' S), which were no different from each other. The incidence of fractures increased exponentially with age, and women had about twice the risk of fractures than men. Hip fracture mainly affects elderly women and presents great variability in incidence between the different regions in Brazil. The incidence of hip fractures in Brazil differed markedly from that reported previously, so that national guidelines and the FRAX model for Brazil should be revised.

Identifiants

pubmed: 35780201
doi: 10.1007/s11657-022-01127-4
pii: 10.1007/s11657-022-01127-4
doi:

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

90

Informations de copyright

© 2022. International Osteoporosis Foundation and National Osteoporosis Foundation.

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Auteurs

Ben-Hur Albergaria (BH)

Osteoporosis Research and Diagnosis Center - CEDOES, Vitoria, Brazil. benhur.gaz@terra.com.br.
Federal University of Espirito Santo, Vitoria, Brazil. benhur.gaz@terra.com.br.

Cristiano A F Zerbini (CAF)

Centro Paulista de Investigação Clinica, Sao Paulo, Brazil.

Vera Lucia Szejnfeld (VL)

Federal University of São Paulo, Sao Paulo, Brazil.

Sergio Ragi Eis (SR)

Osteoporosis Research and Diagnosis Center - CEDOES, Vitoria, Brazil.

Dalisbor Marcelo Weber Silva (DMW)

Medical School of Univille, Joinville, Brazil.

Maria de Fatima Lobato da Cunha (M)

Federal University of Para, Belem, Brazil.

Michael R McClung (MR)

Oregon Osteoporosis Center, Portland, OR, USA.

John A Kanis (JA)

Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.
Mary McKillop Institute for Health Research, Australian Catholic University, Melbourne, Australia.

Eugene V McCloskey (EV)

Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.
Mellanby Centre for Bone Research, MRC and Arthritis Research UK Centre for Integrated Research in Musculoskeletal Ageing, University of Sheffield, Sheffield, UK.

Tatiane Vilaca (T)

Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.

Marise Lazaretti-Castro (M)

Federal University of São Paulo, Sao Paulo, Brazil.

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Classifications MeSH